Handbook of Arsenic Toxicology

Handbook of Arsenic Toxicology
Author: Swaran Jeet Singh Flora
Publsiher: Academic Press
Total Pages: 988
Release: 2023-02-21
Genre: Medical
ISBN: 9780323984713

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Handbook of Arsenic Toxicology, Second Edition presents the latest findings on arsenic, including its chemistry, sources and effects on the environment and human health. The book discusses both acute and chronic effects, discussing many aspects of arsenic, from physical and chemical properties, exposure, epidemiology, organ toxicity, diagnosis, prevention and treatment. Fully updated and revised, this new edition includes new topics on risk assessment, molecular mechanisms of arsenic, advances in the integrated approach to testing, assessment and development, evaluation and application of high content predictive models, and new alternative methods (NAMS) in the context of Adverse Outcome Pathways (AOPs) to assess toxicology. This comprehensive resource allows readers to effectively assess the risks related to arsenic, providing them with all they need to know on arsenic exposure, toxicity and toxicity prevention. Brings together current findings on the effects of arsenic on the environment and human health Includes state-of-the-art techniques in arsenic toxicokinetics, speciation and molecular mechanisms Provides all the information needed for effective risk assessment, prevention and countermeasures

Handbook on the Toxicology of Metals Volume II Specific Metals

Handbook on the Toxicology of Metals  Volume II  Specific Metals
Author: Gunnar F. Nordberg,Max Costa
Publsiher: Academic Press
Total Pages: 1054
Release: 2021-12-01
Genre: Medical
ISBN: 9780128231388

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Handbook on the Toxicology of Metals, Volume II: Specific Metals, Fifth Edition provides complete coverage of 38 individual metals and their compounds. This volume is the second volume of a two-volume work which emphasizes toxic effects in humans, along with discussions on the toxic effects of animals and biological systems in vitro when relevant. The book has been systematically updated with the latest studies and advances in technology. As a multidisciplinary resource that integrates both human and environmental toxicology, the book is a comprehensive and valuable reference for toxicologists, physicians, pharmacologists, and environmental scientists in the fields of environmental, occupational and public health. Contains peer-reviewed chapters that deal with the effects of metallic elements and their compounds on biological systems with a focus on human health effects Includes information on sources, transport, and the transformation of metals in the environment Provides critical information on the properties, use, biological monitoring, dose-response relationships, diagnosis, treatment, and prevention of 38 metallic elements and their compounds

Handbook on the Toxicology of Metals Specific metals

Handbook on the Toxicology of Metals  Specific metals
Author: Lars Friberg,Gunnar Nordberg,Velimir B. Vouk
Publsiher: Elsevier Science & Technology
Total Pages: 756
Release: 1986
Genre: Metals
ISBN: UOM:39015011641050

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Chapters on specific metals include physical and chemical properties, methods and problems of analysis, production and uses, environmental levels and exposures, metabolism, levels in tissues and biological fluids, effects and dose-response relationships, carcinogenicity, mutagenicity, teratogenicity and preventative measures, diagnosis, treatment and prognosis.

The Poisoner s Handbook

The Poisoner s Handbook
Author: Deborah Blum
Publsiher: Penguin
Total Pages: 336
Release: 2011-01-25
Genre: Medical
ISBN: 9781101524893

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Equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is "a vicious, page-turning story that reads more like Raymond Chandler than Madame Curie." —The New York Observer “The Poisoner’s Handbook breathes deadly life into the Roaring Twenties.” —Financial Times “Reads like science fiction, complete with suspense, mystery and foolhardy guys in lab coats tipping test tubes of mysterious chemicals into their own mouths.” —NPR: What We're Reading A fascinating Jazz Age tale of chemistry and detection, poison and murder, The Poisoner's Handbook is a page-turning account of a forgotten era. In early twentieth-century New York, poisons offered an easy path to the perfect crime. Science had no place in the Tammany Hall-controlled coroner's office, and corruption ran rampant. However, with the appointment of chief medical examiner Charles Norris in 1918, the poison game changed forever. Together with toxicologist Alexander Gettler, the duo set the justice system on fire with their trailblazing scientific detective work, triumphing over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice. In 2014, PBS's AMERICAN EXPERIENCE released a film based on The Poisoner's Handbook.

Handbook on the Toxicology of Metals

Handbook on the Toxicology of Metals
Author: Monica Nordberg,Gunnar F. Nordberg,Bruce A. Fowler,Lars Friberg
Publsiher: Elsevier
Total Pages: 1024
Release: 2011-04-28
Genre: Science
ISBN: 9780080546100

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Handbook of the Toxicology of Metals is the standard reference work for physicians, toxicologists and engineers in the field of environmental and occupational health. This new edition is a comprehensive review of the effects on biological systems from metallic elements and their compounds. An entirely new structure and illustrations represent the vast array of advancements made since the last edition. Special emphasis has been placed on the toxic effects in humans with chapters on the diagnosis, treatment and prevention of metal poisoning. This up-to-date reference provides easy access to a broad range of basic toxicological data and also gives a general introduction to the toxicology of metallic compounds. * Covers up-to-date toxicological information on 31 metallic elements and their compounds, each in a separate chapter * New chapters on general chemistry, biological monitoring and biomarkers, essential metals, principles for prevention of the toxic effects of metals, and more

Metal Toxicology Handbook

Metal Toxicology Handbook
Author: Debasis Bagchi,Manashi Bagchi
Publsiher: CRC Press
Total Pages: 692
Release: 2020-11-19
Genre: Health & Fitness
ISBN: 9780429795732

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Heavy metals and metalloids, singly or in combination, induce toxic manifestations either through acute or chronic pathology. In particular, long-term chronic exposure to diverse heavy metals and metalloids to humans and animals can lead to numerous physical, muscular, neurological, nephrological, and diverse degenerative diseases and dysfunctions, including multiple sclerosis, muscular dystrophy, Parkinson’s and Alzheimer’s diseases, cardiovascular disorders, and several others. Recognized heavy metals such as lead, mercury, arsenic, cadmium, thallium, and hexavalent chromium are known for enormous toxicity. The immediate vital signs of acute heavy metal exposure include nausea, vomiting, diarrhea, and acute abdominal pain. Mercury has been identified as the most toxic heavy metal, and mercury poisoning is known as acrodynia or pink disease. Similarly, lead, another toxic heavy metal, was at one time an integral part of painting. Metal Toxicology Handbook further explains and discusses the varying attributes of metals, discussing toxicity, safety, and proper human utilization of metals. Beginning with a broad overview of metals, metalloids, redox biology, and neurodegeneration and going further into the roles, benefits, and toxicity of metals with each section, the text contains 28 chapters from eminent researchers and scientists in their respective fields and is a must-have for anyone researching the potential toxicity in metals. Key Features Discusses the pathology of metal toxicity Highlights the benefits of metals Explains the mechanism and salient features of restoring metabolic homeostasis Highlights dose-dependent beneficial and adverse effects of vanadium safety and toxicity The initial introductory section provides a broad overview of metals, metalloids, redox biology, and neurodegeneration. The second section discusses the pathology of metal toxicity in two chapters, while the third section highlights the mechanism and salient features of restoring metabolic homeostasis in two chapters. The fourth section demonstrates the aspect of radionuclides toxicity. In a change of pace, the fifth section discusses the benefits of metals in four chapters. The sixth section, titled "Toxic Manifestations by Diverse Heavy Metals and Metalloids," provides fourteen chapters that discuss the toxicological mechanism and manifestation of individual metals. The editors have crafted a commentary titled "A Treatise on Metal Toxicity" and summarized a vivid scenario of metal toxicity and its consequences.

King of Poisons

King of Poisons
Author: John Parascandola
Publsiher: Potomac Books, Inc.
Total Pages: 209
Release: 2012-10-31
Genre: Medical
ISBN: 9781597977036

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For centuries, arsenic's image as a poison has been inextricably tied to images of foul play. In King of Poisons, John Parascandola examines the surprising history of this deadly element. From Gustave Flaubert to Dorothy Sayers, arsenic has long held a place in the literary realm as an instrument of murder and suicide. It was delightfully used as a source of comedy in the famous play Arsenic and Old Lace. But as Parascandola shows, arsenic has had a number of surprising real-world applications. It was frequently found in such common items as wallpaper, paint, cosmetics, and even candy, and its use in medical treatments was widespread. American ambassador Clare Boothe Luce suffered from exposure to arsenical paint in her study, and Napoleon's death has long been speculated to be the result of accidental or intentional poisoning. But arsenic poisoning is still a public menace. In the neighborhood surrounding American University in Washington, D.C., the army has undertaken a massive cleanup of artillery shells and bottles containing chemical warfare agents such as arsenical lewisite after a number of workmen and residents became ill. Arsenic contamination of the water supply in Bangladesh and in West Bengal, India, is a major public health problem today as well. From murder to crime fiction, from industrial toxin to chemical warfare, arsenic remains a powerful force in modern life.

Handbook on the Toxicology of Metals Volume I General Considerations

Handbook on the Toxicology of Metals  Volume I  General Considerations
Author: Gunnar F. Nordberg,Max Costa
Publsiher: Academic Press
Total Pages: 798
Release: 2021-11-30
Genre: Medical
ISBN: 9780128232934

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Handbook on the Toxicology of Metals, Fifth Edition, Volume I: General Considerations is the first volume of a two-volume work that gives an overview and covers topics of general importance including reviews of various health effects of trace metals. The book emphasizes toxic effects in humans, along with discussions on the toxic effects of animals and biological systems in vitro when relevant. The book has been systematically updated with the latest studies and advances in technology and contains several new chapters. As a multidisciplinary resource that integrates both human and environmental toxicology, the book is a comprehensive and valuable reference for toxicologists, physicians, pharmacologists, and environmental scientists in the fields of environmental, occupational and public health. Contains peer-reviewed chapters that deal with the effects of metallic elements and their compounds on biological systems Includes information on sources, transport and the transformation of metals in the environment Covers the ecological effects of metals to provide a basis for better understanding of the potential for adverse effects on human health Provides critical information on the properties, use, biological monitoring, dose-response relationships, diagnosis, treatment and prevention of metallic elements and compounds