Handbook Of Basal Ganglia Structure And Function

The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction Features a truly international cast of the preeminent researchers in the field Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases

Handbook of Basal Ganglia Structure and Function, Second Edition, offers an integrated overview of the structural and functional aspects of the basal ganglia, highlighting clinical relevance. The basal ganglia, a group of forebrain nuclei interconnected with the cerebral cortex, thalamus, and brainstem, are involved in numerous brain functions, such as motor control and learning, sensorimotor integration, reward, and cognition. These nuclei are essential for normal brain function and behavior, and their importance is further emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. This updated edition has been thoroughly revised to provide the most up-to-date account of this critical brain structure. Edited and authored by internationally acclaimed basal ganglia researchers, the new edition contains ten entirely new chapters that offer expanded coverage of anatomy and physiology, detailed accounts of recent advances in cellular/molecular mechanisms and cellular/physiological mechanisms, and critical, deeper insights into the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cellular/molecular and cellular/physiological mechanisms, and behavioral and clinical aspects of function and dysfunction Written by international authors who are preeminent researchers in the field Explores, in full, the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases

This volume arose out of the symposium: "The Basal Ganglia: Structure and Function," held at the beginning of September 1983 as a satellite of the 29th International Congress of Physiological Sciences. The symposium took place at Lorne, a village on the ocean 150km south-west of Melbourne in a former holiday guest-house situated beside the beach. The sounds of surf and winter rain on the iron roof provided a background to the proceedings. The symposium was a happy and productive event, among a small group of participants from twelve countries, undistracted by any competing activities in the out-of-season period. Over three days, there were formal papers with lively discussion, as well as posters displayed continuously and available for comment during coffee and lunch breaks. The more philosophical views on the basal ganglia were aired at informal evening discussions after dinner. At the symposium banquet on the final night, the participants voted to form the International Basal Ganglia Society (IBAGS); Malcolm Carpenter was elected Foundation President, with Richard Faull as Organizing Secretary. The book comprises papers prepared by participants after returning home, so that they had opportunities for incorporating fruits of symposium discussions. Some anticipated contributors were finally unable to participate, and a few who presented data preferred not to submit papers for the book.

This volume was generated from papers presented at the Second Triennial Symposium of the International Basal Ganglia Society (IBAGS) held at the University of Victoria, British Columbia, July 21-23, 1986. The meeting was held as a satellite symposium following the XXX Congress of the International Union of Physiological Sciences at Vancouver. IBAGS was founded at a similar satellite symposium held in Lorne, Australia, organized by John S. McKenzie and sponsored by the University of Melbourne. The symposium held in Australia was attended by 50 scientists from 12 different countries. The results of the first symposium, edited by John S. McKenzie, Robert E. Kemm and Lynette N. Wilcock, were published by Plenum Press in 1984 under the title, The Basal Ganglia - Structure and Function. It was decided that the Society should meet on a triennial basis. The time and place for Second IBAGS Symposium were set by A.G. Phillips who served as Chairman of the Program Committee along with I. Divac, S.A. Greenfield and E.T. Rolls and J.S. McKenzie. Michael E. Corcoran of the Department of Psychology, University of Victoria served as the on-site coordinator and arranger for the Symposium. He was ably assisted by Ms. Morag McNeil who handled the details which made the meeting run smoothly.

''Emphasis on new issues and emerging concepts insures that the information presented is still timely...A compelling source of information on recent research in the field.'' ---Journal of Chemical Neuroanatomy, May 1997

In order to focus on principles, each chapter in this work is brief, organized around 1-3 wiring diagrams of the key circuits, with several pages of text that distil the functional significance of each microcircuit

Executive functioning: we measure it, assess it, document its development in youth, track its decline in age and use it as a basis for diagnoses, treatment planning and-of course-theories. Could it be possible that science has spent decades chasing a cognitive phantom? Noting the lack of consensus concerning definition, component skills, and location within the brain, The Myth of Executive Functioning calls basic assumptions, prominent theories, commonly used test methods, and even the phrase executive functioning into question. The book's deceptively simple argument takes an evolutionary/neuroscience look at the cornerstones of cognitive organization, including memory, planning, decision-making and adaptation to novel circumstances. From there, gaps are identified between systems of cognitive control and those behaviors that are evaluated in neuropsychological testing-gaps that contribute to the disconnect between how science views mind and body, brain and behavior. The author's problem-solving metaphor places new emphasis on stimulus processing and on the relationship between movement and thought as he offers thought-provoking perspectives on: The limits of neuropsychological constructs. The components of adaptive thinking. The automatic aspects of problem solving. The left-brain/right-brain dichotomy. Problems with the domain approach to cognition. New paradigms for testing cognitive functioning. A controversial presentation with the potential to change clinical practice and training, The Myth of Executive Functioning will be read, debated and learned from by neuropsychologists, clinical psychologists, psychiatrists, cognitive neuroscientists and rehabilitation specialists.

Principles and Practice of Movement Disorders provides the complete, expert guidance you need to diagnose and manage these challenging conditions. Drs. Stanley Fahn, Joseph Jankovic and Mark Hallett explore all facets of these disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. An accompanying Expert Consult website makes the content fully searchable and contains several hundred video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses. Get just the information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Find the answers you need quickly and easily thanks to a reader-friendly full-color format, with plentiful diagrams, photographs, and tables. Apply the latest advances to diagnosis and treatment of pediatric movement disorders, Parkinson disease, and much more. View the characteristic presentation of each disorder with a complete collection of professional-quality, narrated videos online. Better visualize every concept with new full-color illustrations throughout. Search the complete text online, follow links to PubMed abstracts, and download all of the illustrations, at www.expertconsult.com.