Handbook Of Growth Factors 1994

Volume I of this book provides a comprehensive discussion of the factors involved in regulation of the cell cycle, the general biological properties of growth factors, and the receptor and postreceptor mechanisms of action of these signaling agents. It evaluates the possible role of growth factors in the regulation of proto-oncogene and tumor suppressor gene expression, and the development of neoplastic processes is discussed in detail.

Volume I of this book provides a comprehensive discussion of the factors involved in regulation of the cell cycle, the general biological properties of growth factors, and the receptor and postreceptor mechanisms of action of these signaling agents. It evaluates the possible role of growth factors in the regulation of proto-oncogene and tumor suppressor gene expression, and the development of neoplastic processes is discussed in detail.

Volume I of this book provides a comprehensive discussion of the factors involved in regulation of the cell cycle, the general biological properties of growth factors, and the receptor and postreceptor mechanisms of action of these signaling agents. It evaluates the possible role of growth factors in the regulation of proto-oncogene and tumor suppressor gene expression, and the development of neoplastic processes is discussed in detail.

Volume I of this book provides a comprehensive discussion of the factors involved in regulation of the cell cycle, the general biological properties of growth factors, and the receptor and postreceptor mechanisms of action of these signaling agents. It evaluates the possible role of growth factors in the regulation of proto-oncogene and tumor suppressor gene expression, and the development of neoplastic processes is discussed in detail.

Volume II of Handbook of Growth Factors presents a stimulating discussion of the best-characterized polypeptide growth factors, including insulin, insulin-like growth factors, epidermal growth factor, fibroblast growth factors, neurotrophic growth factors, and transforming growth factors. The structure and function of each growth factor is discussed, as well as its receptor and postreceptor mechanism of action and its role in neoplastic processes. Regulatory peptides with growth factor-like properties such as bombesin, angiotensin, endothelin, atrial natriuretic factor, vasoactive intestinal peptide, and bradykinin are examined in depth. Factors related to the growth of organs such as the prostate, the heart, and the mammary gland are also covered.

Handbook of Growth Factors, Volume III is devoted to hematopoiesis and its regulation by endogenous factors with growth stimulatory and growth inhibitory properties. The book provides detailed discussions on signaling agents related to the regulation of hematopoiesis, including the interleukins, the colony-stimulating factors, the interferons, the tumor necrosis factors, the erythropoietic growth factors, the platelet-derived growth factor, the leukemia inhibitory factor, and the transferrins. The structure and function of each factor is covered in detail, as well as its receptor and postreceptor mechanism of action and its possible role in neoplastic processes. The book also explores the present state of the knowledge about megakaryocyte growth factors and macrophage-derived growth factors.

Comprehensive Human Physiology is a significantly important publication on physiology, presenting state-of-the-art knowledge about both the molecular mechanisms and the integrative regulation of body functions. This is the first time that such a broad range of perspectives on physiology have been combined to provide a unified overview of the field. This groundbreaking two-volume set reveals human physiology to be a highly dynamic science rooted in the ever-continuing process of learning more about life. Each chapter contains a wealth of original data, clear illustrations, and extensive references, making this a valuable and easy-to-use reference. This is the quintessential reference work in the fields of physiology and pathophysiology, essential reading for researchers, lecturers and advanced students.