Handbook Of Stem Cell Transplantation And Cellular Therapy Management

Handbook of Stem Cell Transplantation and Cellular Therapy Management provides an evidence-based practical guide for clinicians and practitioners who treat cancer patients with these challenging and innovative techniques. The handbook begins with chapters on autologous transplantation for myeloma and lymphoma and allogenic transplantation for leukemia, lymphoma, and myelodysplastic syndrome. Further chapters cover the standards of care for managing adverse events related to acute graft-versus-host disease, chronic graft-versus-host disease, infections of bacterial, fungal, and viral nature, lymphoproliferative disease, pulmonary complications, renal complications, and more clinical issues. Concluding chapters address new CAR T-cell therapies, including their mechanisms of action, indications, and unique associated toxicities, in addition to a chapter dedicated to biostatistics and clinical trials. Throughout the book, extensive tables, flow diagrams, and other figures highlight, simplify, and illustrate key concepts. Written by experienced clinicians at the world-renowned Dana Farber Cancer Center and Harvard Medical School in Boston as well as leading experts at other institutions, this stem cell transplantation handbook combines the clinical knowledge, expertise and practical application of these potential life-saving cell therapies in one quick, point-of-care reference. With real-world clinical vignettes interwoven among the chapters, this handbook is an essential resource for anyone managing patients being treated with stem cell transplantation or cellular therapies. Key Features: Provides latest insights and recommendations for managing challenging treatment complications and adverse events Consolidates key information such as diagnosis criteria, disease staging, common complications, and more using detailed tables and diagrams Shares real-world clinical vignette examples, which provide insight into clinical assessment, treatment, and management Emphasizes patient management and best practices Discusses short- and long-term risks for stem cell transplantation and cellular therapy

This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

This updated and expanded edition developed by the Blood and Marrow Stem Cell Transplant team at Oregon Health & Science University Knight Cancer Institute features the latest medical management guidelines and standards of care for hematopoietic stem cell transplant and cellular therapy patients. Spanning the timeline from the initial consultation throughout the transplant process, this handbook begins by providing a general overview of stem cell transplantation and goes on to outline disease-specific indications for stem cell transplantation. It then focuses on transplant complications and ongoing care, and finally explores cellular therapies for hematologic malignancies. Comprehensive and easy-to-use, Blood and Marrow Transplant Handbook: Comprehensive Guide for Patient Care, Third Edition presents a multidisciplinary approach to information for physicians and advanced practice medical providers as well as residents, fellows, and other trainees who care for patients who undergo transplant and immune effector cell therapy.

This open access book provides a concise yet comprehensive overview on how to build a quality management program for hematopoietic stem cell transplantation (HSCT) and cellular therapy. The text reviews all the essential steps and elements necessary for establishing a quality management program and achieving accreditation in HSCT and cellular therapy. Specific areas of focus include document development and implementation, audits and validation, performance measurement, writing a quality management plan, the accreditation process, data management, and maintaining a quality management program. Written by experts in the field, Quality Management and Accreditation in Hematopoietic Stem Cell Transplantation and Cellular Therapy: A Practical Guide is a valuable resource for physicians, healthcare professionals, and laboratory staff involved in the creation and maintenance of a state-of-the-art HSCT and cellular therapy program.

This Open Access new edition of the EBMT handbook with its new format, addresses the latest developments and innovations in hematopoietic cell transplantation and cellular therapy. Consisting of 94 chapters, it has been written by 210 leading experts in the field. Discussing all types of hematopoietic cell transplantation, including selection of stem cell sources, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies and new infections (COVID-19). This book provides an unparalleled description of current practices to enhance readers’ knowledge and practice skills.

Led by authors from MD Anderson’s Stem Cell Transplantation and Cellular Therapy Department, the world’s largest and highly respected program at the forefront of rapidly advancing treatments in the field, Manual of Hematopoietic Cell Transplantation and Cellular Therapies is a comprehensive, focused reference covering the latest clinical developments and applications of stem cell transplant and cellular therapies for hematologic malignancies and solid tumors. This cutting-edge title, with a majority contribution from the MD Anderson Cancer Center and leading faculty from other academic institutions, covers breakthrough cell-based therapies for various diseases including lymphoma, multiple myeloma, leukemia, and select solid tumor and autoimmune diseases. This unique, definitive resource is essential for hematologists, fellows in hematology and immunotherapy, mid-level providers, pharmacists, and oncologists who refer patients for cell-based therapies. Addresses hematologic conditions including leukemia, lymphoma, and myeloma. Offers guidance on hematopoietic cell transplantation for solid tumors. Covers basic science principles, clinical aspects, pharmacology, radiation therapy, and disease-specific guidelines, including prevention and management of complications. Discusses key topics such as hematopoietic cell collection, bone marrow harvesting, umbilical cord blood transplantation, CAR T-cell therapy, and patient/donor selection and preparation of HCT. Features extensive summary boxes, bulleted content, and algorithms throughout for quick and easy reference. Offers team-based, clinically-focused coverage from world-renowned leaders in the field.

This first open access European CAR-T Handbook, co-promoted by the European Society for Blood and Marrow Transplantation (EBMT) and the European Hematology Association (EHA), covers several aspects of CAR-T cell treatments, including the underlying biology, indications, management of side-effects, access and manufacturing issues. This book, written by leading experts in the field to enhance readers’ knowledge and practice skills, provides an unparalleled overview of the CAR-T cell technology and its application in clinical care, to enhance readers’ knowledge and practice skills.