Herbal Bioactive Based Drug Delivery Systems

Herbal Bioactive-Based Drug Delivery Systems: Challenges and Opportunities provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments. Explores standardization, regulation and enhancement issues in herbal bioactives Discusses novel developments, herbal cosmetics and toxicity/interaction issues Provides a comprehensive reference on all aspects of herbal bioactives

This 2-part reference informs readers about the application of drug delivery technologies to herbal medicines. Chapters cover a broad range of major topics on the subject of targeted drug delivery systems. These topics include the application of drug delivery systems for herbal nanomedicines, drug development issues, emerging technologies, adaptations for clinical use, market prospects and challenges of industrial commercialization. Chapters have been contributed by several experts in pharmaceutical chemistry and blend theoretical knowledge with practical aspects of drug delivery. Part II covers the following topics: - Pharmaceutical nanosciences and their application in the delivery of various phytoconstituents - Design of cosmeceutical drug delivery systems: the role of nanotechnology in cosmeceuticals - Transfersomes: a novel vesicular transdermal delivery system - Self-nano/micro emulsified drug delivery systems - Phytosomes - The role of nanomedicines in ocular drug delivery systems - Colloidosomes as an efficient novel drug delivery system: an update - Herbal nanoscience: challenges and regulatory perspectives - Vitamins based nanomedicine approach - Dendrimers: a versatile nanoplatform for advanced targeting and bioactive(s) delivery - Targeted drug delivery systems for cells and cell organelles - Liposomes for herbal drug delivery - AI in pharmacy, herbal medicine and drug delivery: sci-fi or reality? This reference is a valuable resource for scholars that creates awareness of novel drug delivery systems as well as their promising applications in drug targeting, and nanotherapeutics for specific diseases.

This 2-part reference informs readers about the application of drug delivery technologies to herbal medicines. Chapters cover a broad range of major topics on the subject of targeted drug delivery systems. These topics include the application of drug delivery systems for herbal nanomedicines, drug development issues, emerging technologies, adaptations for clinical use, market prospects and challenges of industrial commercialization. Chapters have been contributed by several experts in pharmaceutical chemistry and blend theoretical knowledge with practical aspects of drug delivery. Part I covers the following topics: - Introduction to nanotechnology and herbal-based nanoparticulate systems - Nucleic acid-based therapeutic drug delivery systems - Herbal bioactives: a booster dose for advanced pharmaceutical nanoscience - Pulmonary nano-drug delivery systems - Application of nano-drug delivery systems in improving the therapeutic efficacy of bioactive natural products - PEGylated liposomes - Insulin liposomes - Aquasomes: a promising novel drug carrier - Nanoparticle-aided herbal drugs: therapeutic implications on cholinergic dysfunction with relevance to Alzheimer’s disease - Vitamins based nanomedicine approach - Recent advances in tumor targeting drug delivery systems: fundamentals of advanced pharmaceutical nanoscience - Niosomes: a revolutionary progress in the field of pharmaceutical sciences - Infectious diseases: pharmaceutical nanoscience for targeted drug delivery This reference is a valuable resource for scholars that creates awareness of novel drug delivery systems as well as their promising applications in drug targeting, and nanotherapeutics for specific diseases.

Novel Drug Delivery Systems for Phytoconstituents discusses general principles of drug targeting, construction material and technological concerns of different phytoconstituent in delivery systems. It focuses on the development of novel herbal formulations and summarizes their method of preparation, type of active ingredients, route of administration, biological activity and their applications. It dicusses therapeutic activities of plant derived chemicals, their limitations in clinical applications and novel drug delivery solutions to overcome them to provide better therapeutic effects with controlled and targeted drug delivery. Focus on drug delivery of phytomolecules Act as bridge between natural product scientist and clinical doctors Discusses mechanism of poor bioavailability of herbal molecules Increases awareness towards phytochemical efficacy Summarizes efficient novel delivery systems-based formulations. It extensively covers the applications of novel drug delivery systems including polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid capsules, liposomes, phytosomes, microsphere, transferosomes, and ethosomes. Some chapters are especially focused on anticancer phytodrugs, silymarin, andrographolide, berberine, and curcumin delivery with special emphasis on their application.

Nanotechnology in Herbal Medicine: Applications and Innovations details how nanomaterials can be utilized to improve the therapeutic mechanisms and key properties of herbal drugs. This book guides the reader through the preparation, properties, applications, benefits and challenges of herbal nanoformulations, helping them solve fundamental and applied problems in the area of novel herbal medicines and drug delivery systems. Herbal drugs play a large role in traditional medicines, which are actively used by many cultures across the globe for the treatment of various illnesses and injuries. Despite their widespread use, herbal medicines may lead to possible health risks due to the lack of information on the chemical composition and permitted dosage. Covers a range of nanomaterial types for use in herbal medicine, including polymeric, metallic, carbon-based and magnetic nanoparticles, as well as dendrimers, liposomes, nanogels, and more Explores the variety of biomedical applications for herbal nanoformulations, such as in cancer therapy, cardiovascular disease and wound healing Weighs up the advantages and disadvantages of using nanotechnology in herbal medicine, with a focus on toxicological impact

This book describes the essential and cutting-edge concepts based on the frontier of pharmaceutical research in TCM, underlying scientific principles, and current advancements of drug delivery systems for Chinese medicines, including sustained-release drug delivery systems, trans-nasal drug delivery systems, dermal and transdermal drug delivery systems, etc. Novel carriers and emerging technologies (such as 3D printing) are also covered. The book provides readers with an overall picture of drug delivery systems for Chinese medicines and also yields benefits for the pharmaceutical industry with regard to TCM-based drug development.

This new volume looks at the applications of biomarkers as important tools for herbal drug discovery, presenting research on phytoconstituents with advanced nanotechnological applications for healthcare benefits. Herbal drug discovery based on biomarkers is an emerging area in complementary and alternative medicine that has tremendous potential in healthcare. Conventional medications have limited efficacy and high toxicity, whereas herbal drugs are said to provide wide structural diversity that is not usually seen with conventional/synthetic drug molecules. Recognition of various herbal constituents, such as terpenoids, fatty acids, flavonoids and steroids, are well explored in the management and treatment of various disorders in this volume. These agents target various biomarkers such as nitric oxide (NO), cytokines, chemokines, adhesion molecules, NF- kβ, lipoxygenase (LOX), and arachidonic acid. Biomarkers as Targeted Herbal Drug Discovery: A Pharmacological Approach to Nanomedicines discusses phytoconstituent-based nanotherapeutics with applications for some specific health issues, such as arthritis, leishmanicidal, cardiovascular diseases, cancer, ocular disorders, etc.

Many herbal treatments are chemical substances that are physiologically active but are not involved in the growth and development of the herbs themselves. Maceration, infusion, and decoction, percolation, soxhlet extraction, microwave-assisted extraction, ultrasound-assisted extraction or sonication extraction, accelerated solvent extraction, and supercritical fluid extraction are all methods for extracting and isolating biologically active chemical compounds from herbs. However, the efficacy of herbal medications is often reduced as a result of traditional delivery techniques. This book cover.