High Altitude

​ Over the last decade the science and medicine of high altitude and hypoxia adaptation has seen great advances. High Altitude: Human Adaptation to Hypoxia addresses the challenges in dealing with the changes in human physiology and the particular medical conditions that arise from exposure to high altitude. In-depth and comprehensive chapters cover both the basic science and the clinical consequences of exposure to high altitude. Genetic, cellular, organ and whole body system responses to high altitudes are covered and chapters discuss these effects on a wide range of diseases. Expert authors provide insight into the care of patients with pre-existing medical conditions that fail in some cases to adapt as well as offer insights into how high altitude research can help critically ill patients. High Altitude: Human Adaptation to Hypoxia is an important new volume that offers a window into greater understanding and more successful treatment of hypoxic human diseases.

This pre-eminent work has developed over six editions in response to man's attempts to climb higher and higher unaided, and to spend more time at altitude for both work and recreation. Building on this established reputation, the new and highly experienced authors provide a fully revised and updated text that will help doctors continue to improve the health and safety of all people who visit, live or work in the cold, thin air of high mountains. The sixth edition remains invaluable for any doctor accompanying an expedition or advising patients on a visit to altitude, those specialising in illness and accidents in high places, and for physicians and physiologists who study our dependence on oxygen and the adaptation of the body to altitude.

The basic goal of the volume is to compile the most up to date research on how high altitude affects the behavior, ecology, evolution and conservation status of primates, especially in comparison to lowland populations. Historically, the majority of primate studies have focused on lowland populations. However, as the lowlands have been disappearing, more and more primatologists have begun studying populations located in higher altitudes. High altitude populations are important not only because of their uniqueness, but also because they highlight the range of primate adaptability and the complex variables that are involved in primate evolution. These populations are good examples of how geographic scales result in diversification and/or speciation. Yet, there have been very few papers addressing how this high altitude environment affects the behavior, ecology, and conservation status of these primates. ​

This book discusses the technical changes that take place at high altitude, and reasons in a down-to-earth way how these situations can be sensibly handled. The authors are climbing doctors with first-hand experience of altitude medicine.

HE history of high-altitude physiology and medicine is such a rich and T colorful topic that it is perhaps surprising that no one has undertaken a comprehensive account before. There are so many interesting ramifications, from the early balloonists to the various high-altitude expeditions, culminating in the great saga of climbing Mt. Everest without supplementary oxygen. Underpinning this variety is the basic biological challenge of hypoxia and the ways organisms adapt to it, a subject that is of key importance in medicine and many other life sciences, encountered as it is by organisms throughout the animal kingdom. I hope that this book will be of interest to a wide range of people, from biologists and physiologists to pulmonologists and others who manage patients with hypoxemia. The topic should also appeal to those who love the mountains including trekkers, skiers, climbers, and mountaineers. The book begins with a short introductory chapter to set the scene for the non-scientist. It then follows a general chronological sequence beginning with the Greeks and ending with contemporary events. In some places, however some compromises have been made to group together areas of related interest. For example, in Chapter 4 the controversy about oxygen secretion is traced from the 1870s to the 1930s and includes the Anglo-American Pikes Peak Ex pedition of 1911 and the International High-Altitude Expedition to Cerro de Pasco, Peru during 1921-1922. It makes sense to consider these events together.

A collection of recipes developed by the high altitude baking experts at Colorado State University Cooperative Extension.

Leading authorities on high-altitude physiology contribute to this work, which is divided into three sections: Man at Extreme Altitude; Sleep and Restoration at High Altitude; and Physiology of Permanent Residents of High Altitude. Based on a symposium on physiology at high altitude sponsored by the American Physiological Society, the volume includes several chapters on the achievements of the 1981 American Medical Research Expedition to Mt. Everest, where the first physiological measurements at altitudes above 8,000 meters were recorded. With growing interest in the study of human performance in these conditions, this text marks a lasting achievement in high-altitude physiology.

In my book Introduction to High Altitude Entomology, published in 1962, I summa rized the results of eight years' studies, mainly on the Himalaya. I have since then had the opportunity of studying the collections of high altitude insects from the Alps, Carpathians, Caucasus, Urals, Alai-Pamirs, Tien Shan, Altai and other im portant mountains of the world in different museums and institutions in Europe. Through the courtesy and generosity of the Academy of Sciences of the Union of Soviet Socialist Republics, I was also able to personally collect insects and make valuable field observations on the Caucasus, the Alai-Pamirs, Ala-Tau and the Tien Shan mountains. Through comparative studies I have tried to synthesize the fundamental principles of high altitude entomology. I have described here the distinctive characters of the high altitude environment, the ecological specializations of the high altitude insects, their ecological inter relations and the outstanding peculiarities of their biogeography. I have also pre sented here an outline of the high altitude entomology of the principal mountains of the world, with brief accounts of their orogeny, geology and vegetation. This book differs from all other contributions in the field in its comparative ecological approach and in the fact that the main emphasis is throughout on the evolution of the high altitude ecosystem as an integral part of the orogeny. High mountains are, in all parts of the world, important and independent centres of origin and differ entiation of distinctive and highly specialized ecosystems and faunas.