High Performance Client Server

And he covers all the key topics, with chapters on Middleware, Architecture, Design, Tools, Databases, Replication, Warehousing, and Transaction Monitors.

Proceedings -- Parallel Computing.

How prepared are you to build fast and efficient web applications? This eloquent book provides what every web developer should know about the network, from fundamental limitations that affect performance to major innovations for building even more powerful browser applications—including HTTP 2.0 and XHR improvements, Server-Sent Events (SSE), WebSocket, and WebRTC. Author Ilya Grigorik, a web performance engineer at Google, demonstrates performance optimization best practices for TCP, UDP, and TLS protocols, and explains unique wireless and mobile network optimization requirements. You’ll then dive into performance characteristics of technologies such as HTTP 2.0, client-side network scripting with XHR, real-time streaming with SSE and WebSocket, and P2P communication with WebRTC. Deliver superlative TCP, UDP, and TLS performance Speed up network performance over 3G/4G mobile networks Develop fast and energy-efficient mobile applications Address bottlenecks in HTTP 1.x and other browser protocols Plan for and deliver the best HTTP 2.0 performance Enable efficient real-time streaming in the browser Create efficient peer-to-peer videoconferencing and low-latency applications with real-time WebRTC transports

Visualization and analysis tools, techniques, and algorithms have undergone a rapid evolution in recent decades to accommodate explosive growth in data size and complexity and to exploit emerging multi- and many-core computational platforms. High Performance Visualization: Enabling Extreme-Scale Scientific Insight focuses on the subset of scientific visualization concerned with algorithm design, implementation, and optimization for use on today’s largest computational platforms. The book collects some of the most seminal work in the field, including algorithms and implementations running at the highest levels of concurrency and used by scientific researchers worldwide. After introducing the fundamental concepts of parallel visualization, the book explores approaches to accelerate visualization and analysis operations on high performance computing platforms. Looking to the future and anticipating changes to computational platforms in the transition from the petascale to exascale regime, it presents the main research challenges and describes several contemporary, high performance visualization implementations. Reflecting major concepts in high performance visualization, this book unifies a large and diverse body of computer science research, development, and practical applications. It describes the state of the art at the intersection of scientific visualization, large data, and high performance computing trends, giving readers the foundation to apply the concepts and carry out future research in this area.

A guide for MySQL administrators covers such topics as benchmarking, server performance, indexing, queries, hardware optimization, replication, scaling, cloud hosting, and backup and recovery.

High Performance Computing Systems and Applications contains fully refereed papers from the 15th Annual Symposium on High Performance Computing. These papers cover both fundamental and applied topics in HPC: parallel algorithms, distributed systems and architectures, distributed memory and performance, high level applications, tools and solvers, numerical methods and simulation, advanced computing systems, and the emerging area of computational grids. High Performance Computing Systems and Applications is suitable as a secondary text for graduate level courses, and as a reference for researchers and practitioners in industry.

Over the past several decades, applications permeated by advances in digital signal processing have undergone unprecedented growth in capabilities. The editors and authors of High Performance Embedded Computing Handbook: A Systems Perspective have been significant contributors to this field, and the principles and techniques presented in the handbook are reinforced by examples drawn from their work. The chapters cover system components found in today’s HPEC systems by addressing design trade-offs, implementation options, and techniques of the trade, then solidifying the concepts with specific HPEC system examples. This approach provides a more valuable learning tool, Because readers learn about these subject areas through factual implementation cases drawn from the contributing authors’ own experiences. Discussions include: Key subsystems and components Computational characteristics of high performance embedded algorithms and applications Front-end real-time processor technologies such as analog-to-digital conversion, application-specific integrated circuits, field programmable gate arrays, and intellectual property–based design Programmable HPEC systems technology, including interconnection fabrics, parallel and distributed processing, performance metrics and software architecture, and automatic code parallelization and optimization Examples of complex HPEC systems representative of actual prototype developments Application examples, including radar, communications, electro-optical, and sonar applications The handbook is organized around a canonical framework that helps readers navigate through the chapters, and it concludes with a discussion of future trends in HPEC systems. The material is covered at a level suitable for practicing engineers and HPEC computational practitioners and is easily adaptable to their own implementation requirements.

This volume explores the application of high-performance computing (HPC) technologies to computational drug discovery (CDD) and biomedicine. The first section collects CDD approaches that, together with HPC, can revolutionize and automate drug discovery process, such as knowledge graphs, natural language processing (NLP), Bayesian optimization, automated virtual screening platforms, alchemical free energy workflows, fragment-molecular orbitals (FMO), HPC-adapted molecular dynamic simulation (MD-HPC), and the potential of cloud computing for drug discovery. The second section delves into computational algorithms and workflows for biomedicine, featuring an HPC framework to assess drug-induced arrhythmic risk, digital patient applications relevant to the clinic, virtual human simulations, cellular and whole-body blood flow modeling for stroke treatments, prediction of the femoral bone strength from CT data, and many more subjects. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary software and tools, step-by-step and readily reproducible modeling protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High Performance Computing for Drug Discovery and Biomedicine allows a diverse audience, including computer scientists, computational and medicinal chemists, biologists, clinicians, pharmacologists and drug designers, to navigate the complex landscape of what is currently possible and to understand the challenges and future directions of HPC-based technologies.