Histology Of Ancient Human Bone Methods And Diagnosis

The examination of excavated human bone finds is mainly the domain of anthropologists and forensic pathologists, the former working with ancient and historical specimens, the latter with modern finds. The methodological and diagnostic approaches to these skeletal finds are the same, regardless of the time of burial. For physical an thropology, bodily human relics are dealt with as historical resources which give clues to ancient population structure, population develop ment, life-style and subsistence. They are thus able to help scientists understand the present state of human populations. The identification of the finds, whether species diagnosis or the evaluation of individual parameters such as sex, age at death, body size and shape, kinship and pathology follows the same procedure used by forensic patholo gists, whose task is the identification of bodily relics in cases of crime, mass disaster and the like. However, there are other disciplines which benefit from excavated bone finds. Anatomy gains insights into the morphological variability of the skeleton in time and place. The implications for modern physi cians and pathologists are at least two-fold: pathological specimens are suitable to unravel the distribution of many diseases and the susceptibility of individuals to pathogens in pre-antibiotic populations. In addition to this epidemiological aspect, exhumed specimens often exhibit advanced states of bone disease which are no longer or only very rarely present in today's industrialized populations because of efficient surgical intervention and pharmacological treatment.

This book provides a systematic approach to diagnosing bone lesions in excavated skeletal series and interpreting the significance of such diseases in ancient human populations. Chapters discuss the biology and gross anatomy of normal bone to aid in understanding the bone changes produced by pathological conditions, and cover the major traumatic, infectious, nutritional, metabolic degenerative, and neoplastic diseases of bone. A special section is devoted to establishing nutritional deficiency as the cause of peculiar lesions found in large numbers of excavated crania. The chapter on bone tumors and tumor-like processes defines the gross morphology of each condition to aid in diagnosing dried bone specimens where histology is unavailable.

This volume presents a truly integrated methodological and biocultural approach to the expanding discipline of human palaeopathology. The book provides researchers and practitioners with a comprehensive guide to the main methods and techniques that are currently available for studying diseases and related conditions from human skeletal remains. It also describes the ways in which these methods can be applied to the reconstruction of health and disease in the past. The first part of the book deals with the survival of palaeopathological evidence and provides an up-to-date account of some of the latest techniques for studying disease in ancient remains. These include imaging techniques, such as radiography and CT scanning, and biochemical and histological analyses. Part two discusses the diagnosis and interpretation of particular classes of disease. The emphasis here is on what can be learnt by taking a biocultural or holistic approach to the study of disease frequencies at a population level. Combines theoretical, methodological and diagnostic aspects with key biocultural approaches. Includes overviews of the latest applicable techniques from molecular biology, biochemistry, histopathology and medical imaging. Written by an international team of experts. This book is an invaluable resource for biological anthropologists and archaeologists who study health and disease in past populations. It is also of interest to medical researchers dealing with epidemiological, diagnostic and pathophysiological aspects of diseases, who need a perspective upon the ways in which particular diseases affected earlier generations. Praise from the reviews: “... This book offers an impressive amount of information for both students and more advanced researchers. Its value lies in the vast expertise the contributors have to offer, with all of them being experts with long-standing careers in their respective fields, as well as the geographical distribution of examples that are given to illustrate specific diseases... outstanding and it truly is an important resource for anyone interested in palaeopathology.” PALEOPATHOLOGY NEWSLETTER “The strengths of the book are numerous, but I am especially impressed with the clarity of presentation... I strongly recommend the book, and plan on using it in my classes as assigned reading to emphasize the very complex nature of diagnosis and its essential role of providing baseline information for interpreting health profiles of ancient populations.” THE QUARTERLY REVIEW OF BIOLOGY “It may be asked if we really need yet another book on paleopathology, especially because there are many acclaimed sources available. In this case, the answer must be a resounding ‘‘Yes!’’...Visually and textually, this volume is of exceptional value for guiding future generations of paleopathologists.” AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY "Pinhasi and Mays have produced an excellent, balanced compilation that reflects what is currently happening in paleopathology research and that nicely addresses paleopathology as both discipline and tool, highlighting technical advanced and schooling us on how disease manifests in the human skeleton. This is valuable resource that students and professionals interested in human paloepathology should consider adding to their libraries." AMERICAN JOURNAL OF HUMAN BIOLOGY

A broad understanding of bone and tooth microstructure is necessary for constructing the biological profile of an individual or individuals within a population. Bone Histology: An Anthropological Perspective brings together authors with extensive experience and expertise in various aspects of hard tissue histology to provide a comprehensive discuss

Research Methods in Human Skeletal Biology serves as the one location readers can go to not only learn how to conduct research in general, but how research is specifically conducted within human skeletal biology. It outlines the current types of research being conducted within each sub-specialty of skeletal biology, and gives the reader the tools to set up a research project in skeletal biology. It also suggests several ideas for potential projects. Each chapter has an inclusive bibliography, which can serve as a good jumpstart for project references. Provides a step-by-step guide to conducting research in human skeletal biology Covers diverse topics (sexing, aging, stature and ancestry estimation) and new technologies (histology, medical imaging, and geometric morphometrics) Excellent accompaniment to existing forensic anthropology or osteology works

The first comprehensive global history of the discipline of paleopathology