Hughes Syndrome

In 1983 Graham Hughes described a syndrome in which the blood has a tendency to clot. Hughes syndrome is at the root of diverse conditions such as stroke, leg vein thrombosis and recurrent abortion. Hughes Syndrome addresses the complete range of features produced by this common disorder, which is also known as antiphospholipid syndrome. The condition can affect any organ, and is treated using commonly available drugs including low-dose aspirin and warfarin. This timely book fulfils the need for a cross-disciplinary clinical textbook and contains contributions from the leading international authorities. Hughes Syndrome should be read by anyone who might have a clinical or scientific interest in this condition: rheumatologists, haematologists, obstetricians and neurologists.

Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students provides an in-depth analysis into the main effects of Hughes Syndrome. In 1983, Dr Graham Hughes, and his team in London, described a syndrome and subsequently developed simple blood tests to diagnose the condition. This syndrome is characterised by thrombosis (both in limbs and internal organs), headaches, memory loss, strokes and, in pregnant women, placental clotting and recurrent miscarriage. The syndrome, now known worldwide as Hughes Syndrome, or the Antiphospholipid Syndrome, is common - being responsible for example, for up to 1 in 5 cases of young stroke and more importantly, it is treatable. Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students details the effects of Hughes Syndrome on the major organs, making it a valuable reference tool for students in training.

This second edition is a result from a worldwide surge of interest in antiphospholipid syndrome. This disease, also known as Hughes Syndrome, affects all organs of the body including the placenta, and therefore touches all areas of medicine.Many publications have shown that APS causes miscarriage, strokes, heart attacks and teenage epilepsy. This new edition will see many of the illustrations updated as well as an increase in the number of figures within the chapters, to help the reader understand and treat this disease. It aims to help patients with Hughes Syndrome and their families, as well as trainee doctors , GPs, nurses and midwives.

This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss/complications are explained. The main clinical manifestations, classification criteria and diagnostic tools are identified, and close attention is paid to the nature of the involvement of various organs or organ systems in APS. Specific chapters describe the treatment of the different symptoms, therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome.

This second edition is a result from a worldwide surge of interest in antiphospholipid syndrome. This disease, also known as Hughes Syndrome, affects all organs of the body including the placenta, and therefore touches all areas of medicine.Many publications have shown that APS causes miscarriage, strokes, heart attacks and teenage epilepsy. This new edition will see many of the illustrations updated as well as an increase in the number of figures within the chapters, to help the reader understand and treat this disease. It aims to help patients with Hughes Syndrome and their families, as well as trainee doctors , GPs, nurses and midwives.

Written by the foremost researchers in the field, this book gathers together in a single source the many important clinical associations of antiphospholipid antibodies. Antibody-related clotting mechanisms and their relationship to conditions such as recurrent strokes, chorea, multi infarct dementias, a variety of spinal syndromes, Addison's Disease, recurrent miscarriages, and many more are discussed in depth. The importance of these antibodies in 'Primary,' 'Secondary,' and 'Catastrophic' Antiphospholipid Syndrome is highlighted. Each chapter is devoted to a specific internal system and the clinical effects this syndrome has on that system. This authoritative book is an essential addition to medical libraries as well as an invaluable reference for general physicians, internists, rheumatologists, neurologists, cardiologists, nephrologists, endocrinologists, gastroenterologists, pulmonologists, dermatologists, and obstetricians.

Hughes Syndrome: Highways and Byways is a handy and easy-to-read guide to the main features of Hughes syndrome. There has been worldwide interest in this 'new' syndrome (first described in 1983). A clotting tendency which can potentially affect any organ in the body, it is: * responsible for 1 in 5 recurrent miscarriages (now successfully treated with aspirin and heparin) * responsible for 1 in 5 young (under 45) strokes * a major cause of early heart attacks * responsible for 1 in 5 deep vein thromboses * an important cause of migraine. Hughes Syndrome: Highways and Byways is a valuable resource for professionals with an interest in the subject, as well as general practitioners and patients.

This book contains information on an increasingly common autoimmune disorder. Also called "sticky blood" and Hughes Syndrome, APS makes one's blood clot too easily, creating high risk of stroke, thrombosis, and premature heart attack. It is also implicated in many other health problems including repeated miscarriages, neurological problems, eary dementia and migraines. It is often associated with lupus, and mimics the symptoms of other diseases, including MS. Symptoms include; migraines and headaches, recurrent miscarriage, memory loss, slurred speech, blood clots, poor circulation, muscle pain and cramps, blurred vision, extreme fatigue, epilepsy, strokes, thrombosis and a form of angina. Because of lack of knowledge of APS in the medical establishment, sufferers are often misdiagnosed with MS or other more life-threatening conditions. This book helps the reader identify the symptoms and provides important information on diagnosis and treatment of APS. It contains many moving stories, explaining how people eventually got a diagnosis, their symptoms, the impact of APS on their lives and whether or not treatment has worked. Written in collaboration with Dr. Graham Hughes, the major researcher of APS in the UK, this book provides a clearly written informative look at an important but little-known disease.