Imaging In Movement Disorders Imaging In Movement Disorder Dementias And Rapid Eye Movement Sleep Behavior Disorder

Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder, Volume 144 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including chapters on Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional Magnetic Resonance Imaging of Dementia with Lewy Bodies, Network Imaging in Parkinsonian and Other Movement Disorders: Network Dysfunction and Clinical Correlates, Neuroimaging of Rapid Eye Movement Sleep Behavior Disorder, Hybrid PET-MRI Applications in Movement Disorders, and more. Covers the role of neuroimaging research in movement disorder dementias Presents the importance of imaging techniques as biomarkers of disease progression and treatment response in therapeutic trials

Imaging in Movement Disorders: Imaging in Movement Disorder Dementias and Rapid Eye Movement Sleep Behavior Disorder, Volume 144 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including chapters on Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional Magnetic Resonance Imaging of Dementia with Lewy Bodies, Network Imaging in Parkinsonian and Other Movement Disorders: Network Dysfunction and Clinical Correlates, Neuroimaging of Rapid Eye Movement Sleep Behavior Disorder, Hybrid PET-MRI Applications in Movement Disorders, and more.

This book describes a sleep disorder belonging to the category of parasomnias (i.e. the sleep behavioral and experiential disorders) characterized by abnormal vocal and motor behaviors in the context of vivid dreams and loss of the customary muscle atonia during the stage of sleep called REM sleep. REM-atonia - one of the defining features of REM sleep, along with rapid-eye-movements and a highly activated brain state - serves a protective function, preventing the dreamer from acting-out dreams and becoming injured. REM sleep behavior disorder (RBD) was first described in 1986 by Schenck and colleagues; since then the understanding of the condition has increased exponentially, also pointing out its strong association with the development of neurodegenerative disorders characterized by alpha synuclein deposition, such as Parkinson’s disease, Dementia with Lewy bodies, and Multiple System Atrophy. Furthermore, RBD is now considered one of the earliest markers of ongoing alpha synuclein neurodegeneration, and provides a window of opportunity for testing disease modifying therapies that may slow down or halt the progression of these disorders for which there is currently no cure. Additionally, RBD is today known to be present in more than 50% of patients with narcolepsy-cataplexy, and can also be triggered by the most commonly prescribed antidepressant medications (e.g. SSRIs, venlafaxine). RBD has been documented as occurring, with variable frequency, with virtually every category of neurologic disease and has also helped expand the field of dream research. The volume Editors have pioneered scientific and clinical advances in the field and, partnering with leading sleep clinicians and researchers on this book, have produced an invaluable guide to specialists in sleep medicine, neurology, psychiatry and psychology. There are also strong contributions in this book by leading basic science researchers, and so this book should also appeal to neuroscientists. As stated in the book, "RBD is situated at a strategic and busy crossroads of sleep medicine and the neurosciences. RBD offers great breadth and depth of research opportunities, including extensive inter-disciplinary and multinational research opportunities...RBD is an 'experiment of Nature' in which knowledge from the study of motor-behavioral dyscontrol during REM sleep, with dream-enactment, has cast a broad and powerful light on a multitude of Central Nervous System disturbances, their evolution, and their comorbidities."

Imaging in Movement Disorders: Imaging in Other Movement Disorders and Dementia, Volume 143 provides an up-to-date textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. The book brings together lessons learned from neuroimaging tools in the content of movement disorders, including idiopathic and sporadic forms of Parkinson’s disease, Huntington’s disease, Atypical Parkinsonism, Dystonia, Essential Tremor, and more. Specific chapters cover Neuroimaging Applications in Dystonia, Neuroimaging Applications in Essential Tremor, Neuroimaging applications in Restless Leg Syndrome, Neuroimaging Application in Tourette's Syndrome and TIC Disorders, Neuroimaging Applications in Functional Movement Disorders, and Neuroimaging Applications in Cerebellar Disorders. Addition sections cover Molecular Imaging of Parkinson's Disease Cognitive Impairment, Structural MRI in Parkinson's Disease Cognitive Impairment, Functional MRI in Parkinson's Disease Cognitive Impairment, Molecular Imaging of Dementia with Lewy Bodies, Structural and Functional MRI of Dementia with Lewy Bodies, Transcranial Sonography in Movement Disorders, Imaging transplantation in Movement Disorders, Hybrid PET-MRI Applications in Movement Disorders, amongst other topics. Offers a complete review of the application of neuroimaging tools in Dystonia, Essential Tremor, Restless Leg Syndrome, Tourette’s syndrome, and Tic and Movement Disorders Covers the role of neuroimaging research in movement disorder dementias Presents the importance of imaging techniques as biomarkers of disease progression and treatment response in therapeutic trials

Patients with Parkinson’s disease commonly struggle with sleep disorders that which negatively affect their quality of life. Sleep Considerations in the Management of Parkinson's Disease provides a comprehensive overview of common sleep issues and related topics in in this complex field. Each chapter begins with a case that describes a typical scenario related to a sleep problem in Parkinson’s disease, followed by a discussion of both the sleep problem and the specifics of the case, providing practical, real-world information to help you provide better patient care. Includes concise chapters authored by Dr. Lana Chahine, each carefully reviewed and supplemented by expert contributors in the specific field. Addresses a wide variety of topics including sleep-onset insomnia, nocturnal manifestations of anxiety disorders, REM sleep behavior disorder, restless legs syndrome and periodic limb movements, and excessive daytime sleepiness. Consolidates today's available information and experience in this important area into one convenient resource.

"Acute neurologic diseases encompass a wide spectrum of medical illnesses with neurological manifestations which require rapid clinical, paraclinical and laboratory evaluation as patients are evaluated in the emergency department or acute care clinics. In the last decade, imaging has assumed far greater importance in the initial assessment of these patients, and is responsible for much of the cost and resources in the early, critical evaluation. However the optimal approach to utilization of imaging for thorough, yet efficient and cost-responsible care remains poorly defined for many acute neurologic presentations"--Provided by publisher.

Magnetic Resonance Imaging in Movement Disorders is the first book to focus in detail on MRI in a range of movement disorders. Since MRI was first employed in imaging Parkinson's disease, the number of imaging techniques and their application in diagnosis and management has extended widely. The book shows various imaging strategies ranging from functional, structural and chemical methods as they relate to both motor and non-motor aspects of Parkinson's disease and other conditions such as Huntington's disease and dystonia. Chapters on MRI in surgery and using MRI as a potential outcome measure in clinical trials show the clinical relevance of methods. Novel methods including DTI, tractography and resting case studies are described in detail. The book also summarises the relevance of fMRI to various aspects of movement disorders. Magnetic Resonance Imaging in Movement Disorders is essential reading for neurologists, radiologists and movement disorder specialists.

Imaging Methodology and Applications in Parkinson's Disease, Volume 141, provides an up-to-date and comprehensive textbook on the use of imaging modalities across the spectrum of movement disorders and dementias. Over the last decades, advances in neuroimaging tools has played a pivotal role in expanding our understanding of disease etiology and pathophysiology, identifying biomarkers to monitor disease progression, aiding differential diagnosis, and in the identification of novel targets for therapeutic intervention. This book brings together lessons learned from neuroimaging tools in movement disorders, including chapters on Advances in PET Methodology, Advances in MRI Methodology, Advances in SPECT Methodology, Hybrid PET/MRI Methodology, and more. Provides an up-to-date and comprehensive textbook addressing all aspects of neuroimaging in movement disorders Offers a complete review of advances in core imaging methodology and the application of neuroimaging tools Represents an indispensable educational and research reference of value to all movement disorder specialists, physicians, researchers and students