Immunology Of Infection

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

This concise text explores the interactions between pathogens and the immune system. Taking a disease-based approach, it explains how micro-organisms adapted to growth in human hosts can evade the immune system and cause disease. The opening chapter overviews the innate and adaptive immune responses to microbes. Subsequent chapters are specific to particular pathogens, beginning with their biology and leading on to illustrate mechanisms of adaptation and ensuing consequences. Each of these chapters ends with a summary, review questions and further reading lists. Summaries, review questions and further reading make this book suitable for self-directed study. Infection and Immunity is ideal for any undergraduates taking a course that explores the interaction between pathogens and the human immune system.

The authors describe the main causes of infection that our bodies have to battle against - from bacteria to viruses - and explain the intricate and fascinating way that our bodies respond to infection - from detection of these potentially dangerous organisms, to their ultimate elimination

TEXT WITH CD STUDY GUIDE With a focus on the relatedness of immunology and microbiology, Immunology, Infection, and Immunity covers both the foundation concepts of immunology, among the most exciting in modern biology and medicine, and their application to the real world of diseases and health. This new text combines clear narratives of how the immune system functions relying in many instances on supporting data from experiments. The editors use examples and illustrations depicting basic immunologic processes in conjunction with their role in infectious or other diseases in order to teach both basic and applied aspects of immunology. A chapter on antibody–antigen interactions and measurements of immunologic reactions familiarizes students with the tools of experimental immunology. In addition to an emphasis on infectious diseases, the book focuses strongly on those areas where the immune system does not act when it should – primary and acquired immunodeficiency, and the failure to control cancer – as well as areas where the over–activity or dysregulation of the immune system is a cause of pathology – hypersensitivity reactions, including allergy and asthma, autoimmunity and the unwanted immune responses to transplanted tissues and organs. To bring the full flavor and excitement of immunology to new students, the editors have assembled an outstanding group of contributors with expertise in the multiple areas of immunology who provide the most up–to–date information in this quickly moving field. All of the chapters have standardized thematic and structural aspects to provide critical information in a comprehensive style. Immunology, Infection, and Immunity is ideally suited for upper division and graduate level students as well as medical and dental students with a good background in basic biology, biochemistry, genetics, and cell biology. The text complements traditional views and dogmas about immunology with today′s cutting edge ideas and experimental data describing how the immune system works, some of which are challenging and changing some long–held beliefs about the function of the immune system. Key Features Examines the basic molecular and cellular components of the immune system relative to the pathogenesis and prevention of infectious diseases Concentrates on the way in which the immune system is critical to the pathogenesis and prevention of infectious diseases Focuses on primary and acquired immunodeficiency and immune system dysregulation as causes of pathology Contributions from multiple areas of immunology present current information in a rapidly moving field All chapters have standardized thematic and structural aspects to provide critical information in a comprehensible style Examples and illustrations depict basic immunologic processes in conjunction with their role in infectious or other diseases About the Electronic Study Guide The DLG CD—ROM is an interactive, automated program that organizes each chapter from Immunology, Infection and Immunity into questions, answers, and extensive explanations. The software helps students first through reviewing the book and then helps them quiz themselves and assess their progress. Students can print out or even stop a study session and resume exactly where they left off at their convenience. With the DLG, students will be able to quickly learn new information, retain it longer, and improve their test scores. Students can work at their own pace, measure their performance, and make the most efficient use of their study time. Prepared by Mary J. Ruebush Recommended system requirements: Windows 98/98SE/ME/NT4/2000/XP Pentium Class Processor, 166 MHz or greater 64 MB of RAM 300 MB free disk space Internet connection for registration/activation only

The immune system has evolved in large part to enable organisms to resist microbial infeetion. Given this very fundamental relationship between the immune system and infeetious microbial agents it is entirely appropriate that avolume in this series should be devoted to the immunology of infeetion. Mieroorganisms have long been used as experimental tools by immunologists, and the study of the immune response to viruses and baeteria has eontributed mueh to our understanding of basie immunologieal meehanisms (for example of the meehanism by whieh non-self determinants on eells are reeognized). However there are of eourse important praetieal and elinical reasons for attempting to understand the immunology of infeetions - these inelude the needs for rational design of vaeeines and to understand the pathogenesis of human infeetious diseases. The last deeade or so has seen a resurgenee of interest in infeetious diseases and a reeognition that they remain of importanee and pertinenee to all areas of medicineo This is not just beeause of the advent of AIDS, although that has been a major faetor - the rise in drug-resistant myeobaeterial infeetions and the reeognition of the infeetious aetiology of peptie uleer disease are other illustrations. It should be made elear that this volume deals with aspeets of the immunolgy of baeteria, viruses and fungi - but it does not deal with parasite immunology which it is planned to eover in a separate volume in the series.

Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Both nutrition deficiency and overnutrition can have a significant effect on the risk of infection. Nutrition, Immunity, and Infection focuses on the influence of diet on the immune system and how altering one’s diet helps prevent and treat infections and chronic diseases. This book reviews basic immunology and discusses changes in immune function throughout the life course. It features comprehensive chapters on obesity and the role of immune cells in adipose tissue; undernutrition and malnutrition; infant immune maturation; pre- and probiotics; mechanisms of immune regulation by various vitamins and minerals; nutrition and the aging immune system; nutrition interactions with environmental stress; and immunity in the global health arena. Nutrition, Immunity, and Infection describes the various roles of nutrients and other food constituents on immune function, host defense, and resistance to infection. It describes the impact of infection on nutritional status through a translational approach. Chapters bring together molecular, cellular, and experimental studies alongside human trials so that readers can assess both the evidence for the effects of the food component being discussed and the mechanisms underlying those effects. The impact of specific conditions including obesity, anorexia nervosa, and HIV infection is also considered. Chapter authors are experts in nutrition, immunity, and infection from all around the globe, including Europe, Australia, Brazil, India, and the United States. This book is a valuable resource for nutrition scientists, food scientists, dietitians, health practitioners, and students interested in nutrition and immunity.