Interactive Knowledge Discovery And Data Mining In Biomedical Informatics

One of the grand challenges in our digital world are the large, complex and often weakly structured data sets, and massive amounts of unstructured information. This “big data” challenge is most evident in biomedical informatics: the trend towards precision medicine has resulted in an explosion in the amount of generated biomedical data sets. Despite the fact that human experts are very good at pattern recognition in dimensions of = 3; most of the data is high-dimensional, which makes manual analysis often impossible and neither the medical doctor nor the biomedical researcher can memorize all these facts. A synergistic combination of methodologies and approaches of two fields offer ideal conditions towards unraveling these problems: Human–Computer Interaction (HCI) and Knowledge Discovery/Data Mining (KDD), with the goal of supporting human capabilities with machine learning./ppThis state-of-the-art survey is an output of the HCI-KDD expert network and features 19 carefully selected and reviewed papers related to seven hot and promising research areas: Area 1: Data Integration, Data Pre-processing and Data Mapping; Area 2: Data Mining Algorithms; Area 3: Graph-based Data Mining; Area 4: Entropy-Based Data Mining; Area 5: Topological Data Mining; Area 6 Data Visualization and Area 7: Privacy, Data Protection, Safety and Security.

Comprehensively presents the foundations and leading application research in medical informatics/biomedicine. The concepts and techniques are illustrated with detailed case studies. Authors are widely recognized professors and researchers in Schools of Medicine and Information Systems from the University of Arizona, University of Washington, Columbia University, and Oregon Health & Science University. Related Springer title, Shortliffe: Medical Informatics, has sold over 8000 copies The title will be positioned at the upper division and graduate level Medical Informatics course and a reference work for practitioners in the field.

This book provides a broad overview of the topic Bioinformatics with focus on data, information and knowledge. From data acquisition and storage to visualization, ranging through privacy, regulatory and other practical and theoretical topics, the author touches several fundamental aspects of the innovative interface between Medical and Technology domains that is Biomedical Informatics. Each chapter starts by providing a useful inventory of definitions and commonly used acronyms for each topic and throughout the text, the reader finds several real-world examples, methodologies and ideas that complement the technical and theoretical background. This new edition includes new sections at the end of each chapter, called "future outlook and research avenues," providing pointers to future challenges. At the beginning of each chapter a new section called "key problems", has been added, where the author discusses possible traps and unsolvable or major problems.

The BIRS Workshop “Advances in Interactive Knowledge Discovery and Data Mining in Complex and Big Data Sets” (15w2181), held in July 2015 in Banff, Canada, was dedicated to stimulating a cross-domain integrative machine-learning approach and appraisal of “hot topics” toward tackling the grand challenge of reaching a level of useful and useable computational intelligence with a focus on real-world problems, such as in the health domain. This encompasses learning from prior data, extracting and discovering knowledge, generalizing the results, fighting the curse of dimensionality, and ultimately disentangling the underlying explanatory factors in complex data, i.e., to make sense of data within the context of the application domain. The workshop aimed to contribute advancements in promising novel areas such as at the intersection of machine learning and topological data analysis. History has shown that most often the overlapping areas at intersections of seemingly disparate fields are key for the stimulation of new insights and further advances. This is particularly true for the extremely broad field of machine learning.

Machine learning (ML) is the fastest growing field in computer science, and Health Informatics (HI) is amongst the greatest application challenges, providing future benefits in improved medical diagnoses, disease analyses, and pharmaceutical development. However, successful ML for HI needs a concerted effort, fostering integrative research between experts ranging from diverse disciplines from data science to visualization. Tackling complex challenges needs both disciplinary excellence and cross-disciplinary networking without any boundaries. Following the HCI-KDD approach, in combining the best of two worlds, it is aimed to support human intelligence with machine intelligence. This state-of-the-art survey is an output of the international HCI-KDD expert network and features 22 carefully selected and peer-reviewed chapters on hot topics in machine learning for health informatics; they discuss open problems and future challenges in order to stimulate further research and international progress in this field.

BIOMEDICAL DATA MINING FOR INFORMATION RETRIEVAL This book not only emphasizes traditional computational techniques, but discusses data mining, biomedical image processing, information retrieval with broad coverage of basic scientific applications. Biomedical Data Mining for Information Retrieval comprehensively covers the topic of mining biomedical text, images and visual features towards information retrieval. Biomedical and health informatics is an emerging field of research at the intersection of information science, computer science, and healthcare and brings tremendous opportunities and challenges due to easily available and abundant biomedical data for further analysis. The aim of healthcare informatics is to ensure the high-quality, efficient healthcare, better treatment and quality of life by analyzing biomedical and healthcare data including patient’s data, electronic health records (EHRs) and lifestyle. Previously, it was a common requirement to have a domain expert to develop a model for biomedical or healthcare; however, recent advancements in representation learning algorithms allows us to automatically to develop the model. Biomedical image mining, a novel research area, due to the vast amount of available biomedical images, increasingly generates and stores digitally. These images are mainly in the form of computed tomography (CT), X-ray, nuclear medicine imaging (PET, SPECT), magnetic resonance imaging (MRI) and ultrasound. Patients’ biomedical images can be digitized using data mining techniques and may help in answering several important and critical questions relating to healthcare. Image mining in medicine can help to uncover new relationships between data and reveal new useful information that can be helpful for doctors in treating their patients. Audience Researchers in various fields including computer science, medical informatics, healthcare IOT, artificial intelligence, machine learning, image processing, clinical big data analytics.

Medical Informatics is defined as an interdisciplinary field studying the effective use of biomedical data, information and knowledge for scientific inquiry, problem solving, and decision making, motivated by efforts to improve human health. To emphasize the broad character it is called Biomedical Informatics. The course LV 444.152 consists of the following 12 lectures: 1. Introduction: Computer Science meets Life Sciences, challenges and future directions; 2. Back to the future: Fundamentals of Data, Information and Knowledge; 3. Structured Data: Coding, Classification (ICD, SNOMED, MeSH, UMLS); 4. Biomedical Databases: Acquisition, Storage, Information Retrieval and Use; 5. Semi structured and weakly structured data; 6. Multimedia Data Mining and Knowledge Discovery; 7. Knowledge and Decision: Cognitive Science and Human-Computer Interaction; 8. Biomedical Decision Making: Reasoning and Decision Support; 9. Intelligent Information Visualization and Visual Analytics; 10. Biomedical Information Systems and Medical Knowledge Management; 11. Biomedical Data: Privacy, Safety and Security 12. Methodology for Information Systems: System Design, Usability and Evaluation

This book constitutes the proceedings of the International Conference on Brain Informatics and Health, BIH 2015, held in London, UK, in August/September 2015. The 42 full papers presented were carefully reviewed and selected from 82 submissions. Following the success of past conferences in this series, BIH 2015 has a strong emphasis on emerging trends of big data analysis and management technology for brain research, behavior learning, and real-world applications of brain science in human health and wellbeing.