Investigating The Human Genome
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Investigating the Human Genome
Author | : Moyra Smith |
Publsiher | : FT Press |
Total Pages | : 243 |
Release | : 2011-06-08 |
Genre | : Medical |
ISBN | : 9780132172844 |
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Leading medical genetics scholar Moyra Smith reviews current and recent work in genetics and genomics to assess progress in understanding human variation and the pathogenesis of common and rare diseases in which genetics plays a role. Smith provides an exceptional overview of the most important biomedical progress arising from the greatly increased genetic information base generated by gene mapping and the sequencing of the complete Human Genome. This book addresses into a wide spectrum of topics associated with human genetics and genomics, including: Human origins; migrations and human population diversity gained though genomic analyses. The complexities of psychiatric diseases that are influenced by genetics. The pathogenesis of late-onset neurological diseases such as Alzheimer’s, Parkinsonism, and ALS. Key aspects of protein misfolding. Gene-environment interactions in DNA damage and repair and DNA instability. Micro RNAs and mRNA translation. Epigenetics. New functions for old enzymes in cancer.
Mapping and Sequencing the Human Genome
Author | : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Mapping and Sequencing the Human Genome |
Publsiher | : National Academies Press |
Total Pages | : 128 |
Release | : 1988-01-01 |
Genre | : Science |
ISBN | : 9780309038409 |
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There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Evaluating Human Genetic Diversity
Author | : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Human Genome Diversity |
Publsiher | : National Academies Press |
Total Pages | : 101 |
Release | : 1998-01-19 |
Genre | : Science |
ISBN | : 9780309184748 |
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This book assesses the scientific value and merit of research on human genetic differencesâ€"including a collection of DNA samples that represents the whole of human genetic diversityâ€"and the ethical, organizational, and policy issues surrounding such research. Evaluating Human Genetic Diversity discusses the potential uses of such collection, such as providing insight into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.
Travelling Around the Human Genome
Author | : Bertrand Jordan |
Publsiher | : John Libbey Eurotext |
Total Pages | : 210 |
Release | : 1993 |
Genre | : Gene mapping |
ISBN | : 2855985722 |
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OTA Report on the Human Genome Project
Author | : United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Oversight and Investigations |
Publsiher | : Unknown |
Total Pages | : 140 |
Release | : 1988 |
Genre | : Chromosome mapping |
ISBN | : UCR:31210015475518 |
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Scientific Frontiers in Developmental Toxicology and Risk Assessment
Author | : National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology |
Publsiher | : National Academies Press |
Total Pages | : 348 |
Release | : 2000-12-21 |
Genre | : Nature |
ISBN | : 9780309070867 |
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Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Cracking the Genome
Author | : Kevin Davies |
Publsiher | : JHU Press |
Total Pages | : 358 |
Release | : 2002-10 |
Genre | : Medical |
ISBN | : 0801871409 |
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This newly updated edition sheds light on the secrets of the sequence, highlighting the myriad ways in which genomics will impact human health for generations to come.
Molecular Biology of The Cell
Author | : Bruce Alberts |
Publsiher | : Unknown |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 0815332181 |
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