Leptin Resistance Defeated

The scientific and therapeutic implications of a new way of understanding a common disease. Depression has often been studied, but this multifaceted disease remains far from understood. Here, leading researchers present a major new view of the disorder that synthesizes multiple lines of scientific evidence from neurobiology, mindfulness, and genetics. A comprehensive mind-body approach to understanding, evaluating, and treating this disease.

No more counting carbs, calories, or fat grams! This revolutionary diet plan works with your hormones to curb your appetite, boost your metabolism, take weight off—and never put it on again. Cutting-edge scientific research shows that losing weight is not about carbs, calories, or even willpower—it’s about a hormone called leptin and how it functions in your body. Leptin is your body’s natural weight-loss mechanism: it curbs your appetite and jump-starts your metabolism. And when those hormones are working properly, they make you literally fat resistant! You will lose weight effortlessly and efficiently, and never gain those pounds back. A leading expert in the field of nutritional medicine, Dr. Leo Galland knows that if you’ve struggled to lose weight on diet after diet but still can’t shake those excess pounds, chances are you are “leptin resistant”—your body no longer responds to leptin, making it impossible to slim down, no matter what size portions or how few carbs you eat. But here’s the good news: by adding the right foods to your diet, you can quickly reverse leptin resistance and reprogram your body to start melting away the pounds. The Fat Resistance Diet is the first weight-loss plan designed specifically to combat leptin resistance, using a unique combination of anti-inflammatory and hormone-balancing foods to get your hormones working again. Used by hundreds of Dr. Galland’s patients with remarkable results, the three-phase regimen includes: STAGE 1: A fourteen-day starter program that delivers a loss of ten to fourteen pounds in the first two weeks. Inflammation-fighting superfoods work to trigger rapid weight loss and set your hormones straight. STAGE 2: A ninety-day plan that builds on the benefits of Stage 1 and delivers a loss of at least five pounds a month. You can enjoy a greater variety of foods while still keeping your hormones working overtime. STAGE 3: Sustainable for life, the meal plans in this phase keep your hormones doing their job, even after you reach your target weight, and offer an expanded, flavorful menu. With delicious recipes that are rich in healing carbs, healing fats, and powerful phytonutrients, the diet is a breeze to stick with—there are no hard-to-find ingredients, no expensive supplements, and no complicated proportions to figure out. Best of all, when you make the Fat Resistance Diet part of your life, your hormones will do your weight-loss work for you! This groundbreaking program at last reveals the true secret to weight loss success, and will transform you from a chronic dieter into a lean, fat-fighting machine.

Due to their prevalence, pervasiveness and burden inflicted on men and women of today, psychiatric disorders are considered as one of the most important, sever and painful illnesses. This impairment of cognitive, emotional, or behavioural functioning is in some cases tragic. Aside from knowing the physical organic factors, such as infections, endocrinal illnesses or head injuries, the aetiology of psychiatric disorders has remained a mystery. However, recent advances in psychiatry and neuroscience have been successful in discovering subsequent pathophysiology and reaching associated bio-psycho-social factors. This book consists of recent trends and developments in psychiatry from all over the world, presented in the form of multifarious and comprehensive articles. The first two sections of the book are reserved for articles on schizophrenia and depression, two major illnesses present in this field. The third section of the book is reserved for addiction psychiatry, related not only to socio-cultural but also biological alterations. The last section of the book, titled Biological Neuropsychiatry, consists of three topics - updated molecular biology, fundamental neuroscience and clinical neuropsychiatric conditions. Doubtlessly, this book will be fruitful for future developments and collaboration in world psychiatry.

"Mold Warriors tells you what you need to know about mold illness, how to recognize it, treat it and defeat the arguments posed by employers, insurance companies and U.S. government officials, who still wrongly claim that mold 'doesn't make anyone seriously ill'"--Cover page 4.

Losing weight and successfully maintaining it over the long term is not as much about what you put in your stomach; it's more about what's happening in the brain. In Brain-Powered Weight Loss, psychotherapist and weight management expert Eliza Kingsford shows that more than 90 percent of people who go on diet programs (even healthy ones) fail or eventually regain because they have a dysfunctional relationship with food. Changing this relationship by changing the way you think about and behave around food is what it takes to permanently achieve weight-loss success. Kingsford’s 11-step first-of-its-kind program enlists dozens of mind-altering and behavior-changing exercises and techniques that shows you how to: • Identify and reverse the conscious and unconscious thinking errors and food triggers that lead to the behaviors that drive our food decisions. • Let go of the mindset of going on or off a diet in favor of a conscious quest to pursue a lifestyle of healthy eating and everyday activity--one that can last forever. • Successfully use what Kingsford calls "dealing skills" to outsmart high-risk situations, tame stressful times, and prevent an eating "slip" from leading to a setback or all-out binge. • Find out if you have what emerging research shows is an addiction to certain high-fat and sugar-added, processed foods that can be as powerful as addiction to cigarettes and narcotics. • Design a personal healthy eating program built on Kingsford's 10 Principles of Healthy Eating.

The Handbook of Behavioral Genetics and Phenotyping represents an integrative approach to neurobehavioural genetics; worldwide experts in their field will review all chapters. Advanced overviews of neurobehavioural characteristics will add immense value to the investigation of animal mutants and provide unique information about the genetics and behavioural understanding of animal models, under both normal and pathological conditions. Cross-species comparisons of neurobehavioural phenotypes will pave the way for an evolutionary understanding of behaviour. Moreover, while biological sciences are progressing towards a holistic approach to investigate the complexity of organisms (i.e., “systems biology” approach), an integrated analysis of behavioural phenotyping is still lacking. The Handbook of Behavioral Genetics and Phenotyping strengthens the cross-talk within disciplines that investigate the fundamental basis of behaviour and genetics. This will be the first volume in which traditionally distant fields including genomics, behaviour, electrophysiology, neuroeconomics, and computational neuroscience, among others, are evaluated together and simultaneously accounted for during discussions of future perspectives.

Darwinian medicine looks at the ecological and evolutionary roots of disease. A disease is an interaction between a genome and its biotic or abiotic environment and therefore a disease is essentially an ecological process. Good understanding of ecology and a Darwinian way of thinking can give us novel and useful perspectives on health and disease. If we understand the disease process better, we can certainly prevent, control as well as treat diseases in a better way. Although the thought that the origins of obesity and type 2 diabetes (T2D) might lie in our hunter gatherer adaptations is not new, research over the last decade makes us rethink many of the classical concepts. Brain and behavior is increasingly being recognized as central to all the endocrine, metabolic and immunological changes that earmark type 2 diabetes and other metabolic syndrome disorders. A major change in paradigm appears to be on the horizon and the proposed book intends to speed up the paradigm shift by raising important questions, pointing out flaws and inadequacies in the prevalent paradigm and stimulating radical rethinking which would redirect and refine the line of research as well as bring some fundamental changes in drug discovery and clinical practice. ​

Although depression has been long considered an exclusively mental disorder, this book highlights the importance of recognizing it as a systemic--physical--illness. The chapters herein present key findings from research on animal models before proceding on to examine the "allostatic" load that depression bears on the body, commonly observed patterns of depression, and illnesses that it is likely to adversely effect--through mechanisms other than that of non-compliance with treatment. The authors also explore various diagnostic dilemmas including symptom-driven, phenomenologic approaches, and discuss drug-drug interactions and the use of unique electronic health records as collaborating agents to the physician. Depression as a Systemic Illness emphasizes the need for the primary care physician to be the first agent to care for "garden variety" depressive disorders and the need to alter medical school and residency training to accommodate the development of the necessary skills, knowledge and attitudes to fulfill this goal. Its unique approach and presentation of depression makes it a key resource for clinicians within the fields of both psychiatry and primary care medicine.