Lighting Up The Brain

"Discover the groundbreaking field of optogenetics, a biological technique that uses light to control cells in living tissue. Optogenetics helps researchers understand biochemical processes in live organisms and may someday be used to treat blindness, neural disorders, and other diseases."--

What if neuroscientists could look inside the human brain and watch individual brain cells send signals to one another? What if they could then control these brain cells to direct thoughts and actions? This may sound like science fiction, but it's actually a scientific revolution called optogenetics. Neuroscientists would like to use this new technology on human brains to uncover secrets about how the brain processes information and drives human behavior. Doctors hope to use optogenetics to restore sight and to treat Alzheimer's disease, Parkinson's disease, depression, and other debilitating or deadly health problems. Discover how the innovative work of leaders in the field is poised to radically transform science, medicine, and human health.

An "elegant", "engrossing" (Carol Tavris, Wall Street Journal) examination of what we think we know about the brain and why -- despite technological advances -- the workings of our most essential organ remain a mystery. "I cannot recommend this book strongly enough."--Henry Marsh, author of Do No Harm For thousands of years, thinkers and scientists have tried to understand what the brain does. Yet, despite the astonishing discoveries of science, we still have only the vaguest idea of how the brain works. In The Idea of the Brain, scientist and historian Matthew Cobb traces how our conception of the brain has evolved over the centuries. Although it might seem to be a story of ever-increasing knowledge of biology, Cobb shows how our ideas about the brain have been shaped by each era's most significant technologies. Today we might think the brain is like a supercomputer. In the past, it has been compared to a telegraph, a telephone exchange, or some kind of hydraulic system. What will we think the brain is like tomorrow, when new technology arises? The result is an essential read for anyone interested in the complex processes that drive science and the forces that have shaped our marvelous brains.

Originally published by Viking Penguin, 2014.

This provocative account of our obsession with neuroscience brilliantly illuminates what contemporary neuroscience and brain imaging can and cannot tell us about ourselves, providing a much-needed reminder about the many factors that make us who we are. What can't neuroscience tell us about ourselves? Since fMRI -- functional magnetic resonance imaging -- was introduced in the early 1990s, brain scans have been used to help politicians understand and manipulate voters, determine guilt in court cases, and make sense of everything from musical aptitude to romantic love. br In Brainwashed, psychiatrist and AEI scholar Sally Satel and psychologist Scott O. Lilienfeld reveal how many of the real-world applications of human neuroscience gloss over its limitations and intricacies, at times obscuring -- rather than clarifying -- the myriad factors that shape our behavior and identities. Brain scans, Satel and Lilienfeld show, are useful but often ambiguous representations of a highly complex system. Each region of the brain participates in a host of experiences and interacts with other regions, so seeing one area light up on an fMRI in response to a stimulus doesn't automatically indicate a particular sensation or capture the higher cognitive functions that come from those interactions. The narrow focus on the brain's physical processes also assumes that our subjective experiences can be explained away by biology alone. As Satel and Lilienfeld explain, this "neurocentric" view of the mind risks undermining our most deeply held ideas about selfhood, free will, and personal responsibility, putting us at risk of making harmful mistakes, whether in the courtroom, interrogation room, or addiction treatment clinic. Although brain scans and other neurotechnologies have provided groundbreaking insights into the workings of the human brain, Brainwashed shows readers that the increasingly fashionable idea that they are the most important means of answering the enduring mysteries of psychology is misguided -- and potentially dangerous.

Now out in tradepaper is The Sugar Brain Fix (a revised and updated edition of Diet Rehab), in which best-selling author and brain-health expert, Dr. Mike Dow, shows how sugar affects brain chemistry and provides new research on dieting and hypnosis. What makes a healthy brain? The answer is simpler than you think. In Diet Rehab, Dr. Mike Dow shared a simple, yet powerful plan to help readers kick their food addictions. Since then, Dr. Dow has gone on to become a New York Times best-selling author and has continued to research and publish books extensively on improving brain health. Over the past five years, he's gathered even more data that shows how our standard American diet is harming our brains and our bodies--and what we can do about it. In 2015, the first human study linking the blood-sugar spiking Western diet and a smaller hippocampus was published. There is now scientific proof that sugar is shrinking the brain! With The Sugar Brain Fix, Dr. Dow takes a closer look at how sugar affects brain chemistry, and the ways we can fix it. The book features cutting-edge research and Dr. Dow's modified Mediterranean diet--the best diet for brain health and wellness. The Sugar Brain Fix will also incorporate research about hypnosis, and other activities to naturally boost brain health. At its core, The Sugar Brain Fix is a cognitive behavioral guide for boosting serotonin and dopamine levels in the brain with a new-and-improved diet and natural mind-set shifts, while improving overall health. The diet has a clinically proven, 3-prong approach: 1) eliminate sugar, 2) boost Mediterranean-diet-friendly fats, 3) increase probiotics.

A doctor discovers the surprising truth about marijuana No substance on earth is as hotly debated as marijuana. Opponents claim it’s dangerous, addictive, carcinogenic, and a gateway to serious drug abuse. Fans claim it as a wonder drug, treating cancer, anorexia, AIDS, chronic pain, glaucoma, arthritis, migraines, PTSD, and insomnia. Patients suffering from these conditions need—and deserve—hard facts based on medical evidence, not hysteria and superstition. In Stoned, palliative care physician Dr. David Casarett sets out to do anything—including experimenting on himself—to find evidence of marijuana’s medical potential. He smears mysterious marijuana paste on his legs and samples pot wine. He poses as a patient at a seedy California clinic and takes lessons from an artisanal hash maker. In conversations with researchers, doctors, and patients around the world he learns how marijuana works—and doesn’t—in the real world. Dr. Casarett unearths tales of near-miraculous success, such as a child with chronic seizures who finally found relief in cannabidiol oil. In Tel Aviv, he learns of a nursing home that’s found success giving marijuana to dementia patients. On the other hand, one patient who believed marijuana cured her lung cancer has clearly been misled. As Casarett sifts the myth and misinformation from the scientific evidence, he explains, among other things: • Why marijuana might be the best treatment option for some types of pain • Why there’s no significant risk of lung damage from smoking pot • Why most marijuana-infused beer or wine won’t get you high Often humorous, occasionally heartbreaking, and full of counterintuitive conclusions, Stoned offers a compassionate and much-needed medical practitioner’s perspective on the potential of this misunderstood plant.

“[Fine’s] sharp tongue is tempered with humor. . . . Read this book and see how complex and fascinating the whole issue is.”—The New York Times It’s the twenty-first century, and although we tried to rear unisex children—boys who play with dolls and girls who like trucks—we failed. Even though the glass ceiling is cracked, most women stay comfortably beneath it. And everywhere we hear about vitally important “hardwired” differences between male and female brains. The neuroscience that we read about in magazines, newspaper articles, books, and sometimes even scientific journals increasingly tells a tale of two brains, and the result is more often than not a validation of the status quo. Women, it seems, are just too intuitive for math; men too focused for housework. Drawing on the latest research in neuroscience and psychology, Cordelia Fine debunks the myth of hardwired differences between men’s and women’s brains, unraveling the evidence behind such claims as men’s brains aren’t wired for empathy and women’s brains aren’t made to fix cars. She then goes one step further, offering a very different explanation of the dissimilarities between men’s and women’s behavior. Instead of a “male brain” and a “female brain,” Fine gives us a glimpse of plastic, mutable minds that are continuously influenced by cultural assumptions about gender. Passionately argued and unfailingly astute, Delusions of Gender provides us with a much-needed corrective to the belief that men’s and women’s brains are intrinsically different—a belief that, as Fine shows with insight and humor, all too often works to the detriment of ourselves and our society.