Mad Cow Disease Bovine Spongiform Encephalopathy

This book presents important analyses of current issues in BSE (bovine spongiform encephalopathy or "mad cow disease") as a fatal neurological disease of cattle, believed to be transmitted mainly by feeding infected cattle parts back to cattle. More than 187,000 cases have been reported world-wide, 183,000 of them in the United Kingdom (UK) where BSE was first identified in 1986. The annual number of new cases has declined steeply since 1992. Humans who eat contaminated beef are believed susceptible to a rare but fatal brain wasting disease, variant Creutzfeldt-Jakob Disease (vCJD). About 160 people have been diagnosed with vCJD since 1986, most in the UK and none linked to any Canadian or U.S. meat consumption.

The alarm sounded by Canada's confirmed case of bovine spongiform encephalopathy (BSE) has reaffirmed the exigency of establishing improved safeguards and more aggressive surveillance protocols in North America and around the world. Research converging on the probable causative agent--prion proteins--calls for intensive assessment of the headway gained in tracing prions, testing for transmissible neurodegenerative diseases, and developing methods for cornering the epidemic. With an illustrious panel of 36 international contributors, this timely book marshals techniques for prion protein assay and diagnosis of transmissible spongiform encephalopathies (TSEs).

"How the Cows Turned Mad tells the story of a disease that continues to elude on many levels. Yet science has come far in understanding its origins, incubation, and transmission. This book is a case history that illuminates the remarkable progression of science."--BOOK JACKET.

Explains mad cow disease, what it is, how it is passed from cows to humans, and possible treatment options.

Explains what mad cow disease is, how it is transmitted, the effects on animals and humans, and how it is controlled.

Through mid-May 2007, the United States had confirmed three cases of bovine spongiform encephalopathy (BSE, or "mad cow disease"): the first in December 2003 in a Canadian-born cow found in Washington state, the second in June 2005 in cow in Texas, and the third in March 2006 in a cow in Alabama. Shortly after the first case, U.S. Department of Agriculture (USDA) and other officials announced measures to improve existing safeguards against the introduction and spread of BSE. Previously, the major safeguards were: (1) USDA restrictions on imports of ruminants and their products from countries with BSE; (2) a ban on feeding most mammalian proteins to cattle and other ruminants, issued by the Food and Drug Administration (FDA); and (3) a targeted domestic surveillance program by USDA's Animal and Plant Health Inspection Service (APHIS), the agency responsible for animal health monitoring and disease control.

The aim of this book is to publicise and bring to a wider audience the concept that the cause of two neurological diseases, namely multiple sclerosis (MS) and “mad cow disease” also known as “bovine spongiform encephalopathy” are related through exposure to a common microbe Acinetobacter which is found in human sinuses, on skin and in the soil. An infection is the cause of a neurological disease in man and in animals. Elevated levels of antibodies to Acinetobacter have been found in multiple sclerosis patients as well as in ruminants who have been described as suffering from “mad cow disease” following exposure to contaminated feed supplements. The overall objective and scope of this book is to inform the audience, the reader, that multiple sclerosis may be linked to a microbe Acinetobacter which carries molecular structures resembling myelin, the outer sheath covering of neurons.