Management Guidelines For Head And Neck Cancer

Tumor biology varies at different subsites in the oral cavity, and therefore carcinoma of the gingivo-buccal sulcus (also known as Indian cancer) behaves differently from carcinoma of the tongue. Oral cancer is very often diagnosed at an advanced stage with neck metastasis, and most cases have a guarded prognosis. Loco-regional recurrences are frequent and morbidity following treatment is considerable. However, results have improved in recent years, particularly in early and certain advanced stages, due to better imaging and case selection, improved surgical techniques, including those for reconstructive surgery, a multidisciplinary team approach and a better understanding of tumor biology and prognostic factors. This book comprehensively and systematically reviews all these aspects of diagnostic and therapeutic advances in oral cancer, particularly discussing early detection, epidemiology, chemoprevention and current research. Written by specialists who are active leaders in basic sciences or clinical fields, the chapters address individual and collective issues in managing patients with oral cancer, and provide insights into various treatment approaches. The authors share their knowledge and experience and provide extensive literature sources to encourage clinicians to be flexible, innovative and help them make the best, educated decisions for individual patients.

​This second edition ​provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management. Head-and-neck cancers are a complex clinical entity and their response to treatment is also known to vary markedly in function of host-related factors. Notwithstanding the impressive progresses observed in the field of imaging, head and neck cancers are often diagnosed at a late stage and the presence of locally advanced disease in a significant number of patients implies the use of aggressive treatments in order to both ensure local disease control and reduce distant metastasis risks. In comparison with the first edition, Head and Neck Cancer, Second Edition provides a detailed update of innovative concepts in chemo- and bio-radiation, viral infection impact on tumor growth and response to treatment, and impact of tumor- and host-related factors on treatment outcome.

This concise handbook has a unique approach and covers all important aspects of head and neck cancers from basic topics like carcinogenesis to advanced treatment options such as immunotherapy, electrochemotherapy, and robotic surgery in a succinct way. As every treatment center manages its patients with a different modality as per their institutional protocol, this book endeavors to standardize the processes by discussing the management of cancers of all anatomic areas in view of the National Comprehensive Cancer Network (NCCN) guidelines, which is the committee that prepares protocols for management of cancers and every head and which neck oncosurgeons must adhere to for their clinical practice. Key Features Explains the topics through flowcharts and diagrammatic representations that are helpful for exam preparation This book aims to serve as a valuable resource for postgraduate residents of maxillofacial surgery, ENT and otolaryngology, general surgery, plastic surgery, and junior specialists Serves as a comprehensive, evidence-based quick reference for the clinician on the go