Mechanism

The mechanical philosophy first emerged as a leading player on the intellectual scene in the early modern period—seeking to explain all natural phenomena through the physics of matter and motion—and the term mechanism was coined. Over time, natural phenomena came to be understood through machine analogies and explanations and the very word mechanism, a suggestive and ambiguous expression, took on a host of different meanings. Emphasizing the important role of key ancient and early modern protagonists, from Galen to Robert Boyle, this book offers a historical investigation of the term mechanism from the late Renaissance to the end of the seventeenth century, at a time when it was used rather frequently in complex debates about the nature of the notion of the soul. In this rich and detailed study, Domenico Bertoloni Meli focuses on strategies for discussing the notion of mechanism in historically sensitive ways; the relation between mechanism, visual representation, and anatomy; the usage and meaning of the term in early modern times; and Marcello Malpighi and the problems of fecundation and generation, among the most challenging topics to investigate from a mechanistic standpoint.

INTRODUCTION BY MISHA GLENNY, author of McMafia A gripping narrative of power, corruption and greed, The Mechanism is the true story of how a simple investigation into money laundering uncovered the biggest corruption scandal in human history. When a small team of investigators discovered that a black market currency dealer was operating out of a Brazilian petrol station, they could never have imagined that their work would destroy the government and lead to the impeachment of two presidents. As the trail leads further and further into the centre of power, the search for the truth and pursuit of justice become ever more crucial. Taut and riveting, with more plot twists than the most compelling political thriller, The Mechanism is an essential work of non-fiction that exposes the rottenness caused when politicians and big businesses believe they are above the law.

"Compliant Mechanisms" beschreibt eine besonders exakte, flexible und zuverlässige Entwurfsmethode im Maschinenbau, vorgestellt von einem international anerkannten Experten. Einem allgemeinen Überblick folgt die Erläuterung fortgeschrittener, moderner, zum Teil hochspezialisierter Anwendungen.

This book is open access under a CC BY license. This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness. Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions. The book offers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental exposures.

What is the best way to auction an asset? How should a group of people organize themselves to ensure the best provision of public goods? How should exchanges be organized? In An Introduction to the Theory of Mechanism Design, Tilman Börgers addresses these questions and more through an exploration of the economic theory of mechanism design. Mechanism design is reverse game theory. Whereas game theory takes the rules of the game as a given and makes predictions about the behavior of strategic players, the theory of mechanism design goes a step further and selects the optimal rules of the game. A relatively new economic theory, mechanism design studies the instrument itself as well as the results of the instrument. An Introduction to the Theory of Mechanism Design provides rigorous but accessible explanations of classic results in the theory of mechanism design, such as Myerson's theorem on expected revenue maximizing auctions, Myerson and Satterthwaite's theorem on the impossibility of ex post efficient bilateral trade with asymmetric information, and Gibbard and Satterthwaite's theorem on the non-existence of dominant strategy voting mechanisms. Börgers also provides an examination of the frontiers of current research in the area with an original and unified perspective that will appeal to advanced students of economics.

'...the history of economic theory at its best.'-EASTERN ECONOMIC JOURNAL

This volume addresses fundamental issues in the philosophy of science in the context of two most intriguing fields: biology and economics. Written by authorities and experts in the philosophy of biology and economics, Mechanism and Causality in Biology and Economics provides a structured study of the concepts of mechanism and causality in these disciplines and draws careful juxtapositions between philosophical apparatus and scientific practice. By exploring the issues that are most salient to the contemporary philosophies of biology and economics and by presenting comparative analyses, the book serves as a platform not only for gaining mutual understanding between scientists and philosophers of the life sciences and those of the social sciences, but also for sharing interdisciplinary research that combines both philosophical concepts in both fields. The book begins by defining the concepts of mechanism and causality in biology and economics, respectively. The second and third parts investigate philosophical perspectives of various causal and mechanistic issues in scientific practice in the two fields. These two sections include chapters on causal issues in the theory of evolution; experiments and scientific discovery; representation of causal relations and mechanism by models in economics. The concluding section presents interdisciplinary studies of various topics concerning extrapolation of life sciences and social sciences, including chapters on the philosophical investigation of conjoining biological and economic analyses with, respectively, demography, medicine and sociology.

It has been said that new discoveries and developments in the human, social, and natural sciences hang “in the air” (Bowler, 1983; 2008) prior to their consummation. While neo-Darwinist biology has been powerfully served by its mechanistic metaphysic and a reductionist methodology in which living organisms are considered machines, many of the chapters in this volume place this paradigm into question. Pairing scientists and philosophers together, this volume explores what might be termed “the New Frontiers” of biology, namely contemporary areas of research that appear to call an updating, a supplementation, or a relaxation of some of the main tenets of the Modern Synthesis. Such areas of investigation include: Emergence Theory, Systems Biology, Biosemiotics, Homeostasis, Symbiogenesis, Niche Construction, the Theory of Organic Selection (also known as “the Baldwin Effect”), Self-Organization and Teleodynamics, as well as Epigenetics. Most of the chapters in this book offer critical reflections on the neo-Darwinist outlook and work to promote a novel synthesis that is open to a greater degree of inclusivity as well as to a more holistic orientation in the biological sciences.