Meningiomas

This book provides a comprehensive overview of the multidisciplinary management of meningiomas, followed by evaluation and management considerations along a spectrum of benign to more malignant behavior. It outlines the management of presumed Grade 1 tumors and how to identify features of tumors radiographically and clinically that may support a benign course rather than aggressive and vice versa. Following a stepwise progression from simple to complex, chapters introduce and tackle more aggressive meningiomas and tumor recurrence (of all Grades), with paradigms for evaluation and treatment. Tumor biology and genomics are fundamental and largely focused in the book. More recent findings which have directed personalized medicine and clinical trials are also addressed. Meningiomas: Comprehensive Strategies for Management addresses all aspects of the evaluation and care of patients with all WHO grades of meningiomas. It is highly informative and provides clarity for a wide audience of neurosurgeons, reconstructive surgeons, oncologists, neurologists, radiation oncologists, pathologists, radiologists, residents and students who treat these patients and those who are training for a career in managing patients with these potentially challenging tumors.

The overall incidence of meningiomas, particularly in the developed countries, is rising due to a growing size of the aging population, with people living longer and enjoying healthier lives than ever before. Additionally, an increased utilization of imaging studies such as computer tomography (CT) and magnetic resonance (MR) for routine evaluation of closed head injuries, paranasal sinus problems and various non-specific neurological symptoms, ranging from headaches to dizziness, has contributed to enhanced detection of incidental meningiomas. The book contains the most up-to-date information in all matters related to meningiomas, and is written by multiple contributors - internationally recognized experts in their respective fields from Asia, USA and Europe. This is an essential reference guide to neurosurgeons and neurologists (in training and in practice), as well as medical libraries, throughout the world.

Al-Mefty's Meningiomas, Second Edition is the definitive guide to meningioma diagnosis, treatment, and surgery, and reflects over a decade of major advances in the diagnosis and management of both intracranial and spinal meningiomas since the first edition was published.The text begins with important information on anatomy, pathology, and epidemiology, followed by clinical and preoperative considerations. The expert authors then provide detailed descriptions of state-of-the-art surgical approaches listed by anatomical site and special operative considerations for intracranial meningiomas. The book closes with incisive discussion of breakthroughs in radiosurgery, radiotherapy and chemotherapy.Features[li]New to this edition: information on molecular biology, natural history and growth rates, the rise of radiosurgery as a viable treatment option, and much more[/li][li]Over 500 high-quality radiographic images and full-color illustrations demonstrate anatomy and surgery[/li][li]In-depth coverage of intraoperative MRI and endoscopic resection[/li][li]Key topics often missing from other meningiomas texts including caseload management, and postoperative quality of life issues[/li]This landmark reference will enhance the precision and surgical skills of every clinician or resident in neurosurgery or neurology.

Meningiomas, Volume 169, Part One, serves as a comprehensive review of the neurosurgical issues surrounding this extremely common brain tumor. Few procedures in surgery are more immediately formidable than an attack upon a large tumor of this type. In this volume of the Handbook of Clinical Neurology, experts in the field - from basic scientists to skilled neurosurgeons - have provided up-to-date synopses of each topic as it relates to this class of tumor. Surgical and radiation therapy, which remain the mainstays of treatment, are a major focus, but coverage also includes potential molecular avenues for the development of effective medical treatments.

This book is an in depth review of the most recent advances in the histopathology, molecular studies, radiology, and management of meningioma. This book contains a separate chapter about pediatric meningioma, with an emphasis on their distinctive features compared to their adult counterparts. This book also addresses several aspects of meningiomas including extradural meningiomas and embolized meningiomas. These aspects have been traditionally poorly explored in the literature. We believe that this book will be positively received by pathologists, neuro-radiologists, and neuro-oncologists alike.

Meningiomas, Volume 170, Part Two, discusses tumors that arise from the coverings of the brain and spinal cord. In this updated volume of the Handbook of Clinical Neurology, experts in the field - from basic scientists to skilled neurosurgeons, provide up-to-date synopses of each topic as it relates directly to this class of tumor. Surgical and radiation therapy, which remain the mainstays of treatment, are a major focus, but coverage also includes potential molecular avenues for the development of effective medical treatments. This book serves as a comprehensive review of the neurosurgical issues surrounding this extremely common brain tumor. Few procedures in surgery are more immediately formidable than an attack upon a large tumor of this type, hence the greatest challenge of treatment is the need to complete tumor removal without creating new neurologic deficit. Provides current reviews of neurosurgical issues, such as endoscopic surgery, molecular biology of meningiomas, and the role of different radiation oncology treatment modalities and drug therapies Addresses multiple patient populations – children, elderly and those with multiple or radiation-induced tumor Offers a strong focus on anatomy and surgical approaches Edited work featuring leaders in neurosurgery and neuro-oncology around the globe – the broadest, most expert coverage available

Although surgery of the skull base still represents a frontier involving different specialties, it is increasingly being accepted and recognized as a special area po sing both unique diagnostic and surgical challenges and specific requirements. This is the prime reason that colleagues involved in the management of skull base processes need special training stressing the different surgical approaches required either at different times or to reach the different areas of this intriguing anatomi cal landmark. Although the advent of microsurgical techniques and advanced diagnostic mo dalities - high-resolution computed tomography, magnetic resonance imaging (MRI) and MR-angiography, and supers elective endovascular protocols - in the last 25 years has brought significant improvements, such as the recent advances in endovascular treatment, a number of different kinds of limitations still persist. This is especially so in the case of skull base meningiomas, the pathological entity most frequently affecting this area which the neurosurgeon is confronted with in daily practice. Besides understanding the intrinsic characteristics of the different pathological entities which involve the skull base, it is the responsibility of physi cians to know and employ the expanded neurosurgical options in the most effecti ve and appropriate way.

This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.