Microbial Essentialism

Microbial Essentialism: An Industrial Prospective refers to properties specifically possessed by microbes such as secretion of metabolites which make them unique and can be employed by industries. These microorganisms can be commercially exploited for beneficial purposes such as the production of whole microbial cells or their products for direct use or as starting raw material in the manufacture of other commercial products which can contribute to large-scale and profit-oriented businesses. Microbial Essentialism: An Industrial Prospective reviews the newest techniques, approaches, and options in the use of microorganisms for the manufacture of industrially important products such as pharmaceuticals, industrial enzymes, chemicals, proteins, foods and beverages, and fuels. It covers fundamental principles of established and innovative industrial microbiology and biotechnology processes and products. It also discusses industrial microorganisms and the technology required for large-scale cultivation and isolation of fermentation products. Covers key aspects of microbial physiology, exploring the versatility of microorganisms and their diverse metabolic activities and products Provides methods and various traditional and novel applications of microorganisms to industrial processes Contributed by a multidisciplinary group of experts who offer not only a thorough evaluation of the primary literature, but also invaluable first-hand experience in industrial microbiology and biotechnology

This book develops a new multimodal theoretical model of contagion for interdisciplinary scholars, featuring contributions from influential scholars spanning the fields of medical humanities, philosophy, political science, media studies, technoculture, literature, and bioethics. Exploring the nexus of contagion's metaphorical and material aspects, this volume contends that contagiousness in its digital, metaphorical, and biological forms is a pervasively endemic condition in our contemporary moment. The chapters explore both endemicity itself and how epidemic discourse has become endemic to processes of social construction. Designed to simultaneously prime those new to the discourse of humanistic perspectives of contagion, complicate issues of interest to seasoned scholars of science and technology studies, and add new topics for debate and inquiry in the field of bioethics, Endemic will be of wide interest for researchers and educators.

Individuals are things that everybody knows—or thinks they do. Yet even scholars who practice or analyze the biological sciences often cannot agree on what an individual is and why. One reason for this disagreement is that the many important biological individuality concepts serve very different purposes—defining, classifying, or explaining living structure, function, interaction, persistence, or evolution. Indeed, as the contributors to Biological Individuality reveal, nature is too messy for simple definitions of this concept, organisms too quirky in the diverse ways they reproduce, function, and interact, and human ideas about individuality too fraught with philosophical and historical meaning. Bringing together biologists, historians, and philosophers, this book provides a multifaceted exploration of biological individuality that identifies leading and less familiar perceptions of individuality both past and present, what they are good for, and in what contexts. Biological practice and theory recognize individuals at myriad levels of organization, from genes to organisms to symbiotic systems. We depend on these notions of individuality to address theoretical questions about multilevel natural selection and Darwinian fitness; to illuminate empirical questions about development, function, and ecology; to ground philosophical questions about the nature of organisms and causation; and to probe historical and cultural circumstances that resonate with parallel questions about the nature of society. Charting an interdisciplinary research agenda that broadens the frameworks in which biological individuality is discussed, this book makes clear that in the realm of the individual, there is not and should not be a direct path from biological paradigms based on model organisms through to philosophical generalization and historical reification.

The first in-depth study of Japanese fermentation science in the twentieth century. The Arts of the Microbial World explores the significance of fermentation phenomena, both as life processes and as technologies, in Japanese scientific culture. Victoria Lee’s careful study documents how Japanese scientists and skilled workers sought to use the microbe’s natural processes to create new products, from soy-sauce mold starters to MSG, vitamins to statins. In traditional brewing houses as well as in the food, fine chemical, and pharmaceutical industries across Japan, they showcased their ability to deal with the enormous sensitivity and variety of the microbial world. Charting developments in fermentation science from the turn of the twentieth century, when Japan was an industrializing country on the periphery of the world economy, to 1980 when it had emerged as a global technological and economic power, Lee highlights the role of indigenous techniques in modern science as it took shape in Japan. In doing so, she reveals how knowledge of microbes lay at the heart of some of Japan’s most prominent technological breakthroughs in the global economy. At a moment when twenty-first-century developments in the fields of antibiotic resistance, the microbiome, and green chemistry suggest that the traditional eradication-based approach to the microbial world is unsustainable, twentieth-century Japanese microbiology provides a new, broader vantage for understanding and managing microbial interactions with society.

Filling a major gap in the philosophy of biology by examining central philosophical issues in microbiology, this book is aimed at philosophers and scientists who wish to gain insight into the basic philosophical issues of microbiology. Topics are drawn from evolutionary microbiology, microbial ecology, and microbial classification.

This advanced textbook provides a unique overview of the microbial communities (normal indigenous microbiota) inhabiting those regions of the human body that are exposed to the external environment, including the skin, eyes, oral cavity and the respiratory, urinary, reproductive and gastrointestinal tracts. In order to understand why particular organisms are able to colonise an anatomical region and why the resulting microbial community has a particular composition, an ecological approach is essential. Consequently, the key anatomical and physiological characteristics of each body site are described throughout the book. The crucial roles of the indigenous microbiota in protecting against exogenous pathogens, regulating the development of our immune system and mucosae, and providing nutrients are also discussed. The involvement of these organisms in infections of healthy and debilitated individuals are discussed throughout and methods of manipulating the composition of the indigenous microbiota for the benefit of human health are also described.

Individually and collectively, resident microbes play important roles in host health and survival. Shaping and shaped by their host environments, these microorganisms form intricate communities that are in a state of dynamic equilibrium. This ecologic and dynamic view of host-microbe interactions is rapidly redefining our view of health and disease. It is now accepted that the vast majority of microbes are, for the most part, not intrinsically harmful, but rather become established as persistent, co-adapted colonists in equilibrium with their environment, providing useful goods and services to their hosts while deriving benefits from these host associations. Disruption of such alliances may have consequences for host health, and investigations in a wide variety of organisms have begun to illuminate the complex and dynamic network of interaction - across the spectrum of hosts, microbes, and environmental niches - that influence the formation, function, and stability of host-associated microbial communities. Microbial Ecology in States of Health and Disease is the summary of a workshop convened by the Institute of Medicine's Forum on Microbial Threats in March 2013 to explore the scientific and therapeutic implications of microbial ecology in states of health and disease. Participants explored host-microbe interactions in humans, animals, and plants; emerging insights into how microbes may influence the development and maintenance of states of health and disease; the effects of environmental change(s) on the formation, function, and stability of microbial communities; and research challenges and opportunities for this emerging field of inquiry.

This collection of essays discusses fascinating aspects of the concept that microbes are at the root of all ecosystems. The content is divided into seven parts, the first of those emphasizes that microbes not only were the starting point, but sustain the rest of the biosphere and shows how life evolves through a perpetual struggle for habitats and niches. Part II explains the ways in which microbial life persists in some of the most extreme environments, while Part III presents our understanding of the core aspects of microbial metabolism. Part IV examines the duality of the microbial world, acknowledging that life exists as a balance between certain processes that we perceive as being environmentally supportive and others that seem environmentally destructive. In turn, Part V discusses basic aspects of microbial symbioses, including interactions with other microorganisms, plants and animals. The concept of microbial symbiosis as a driving force in evolution is covered in Part VI. In closing, Part VII explores the adventure of microbiological research, including some reminiscences from and perspectives on the lives and careers of microbe hunters. Given its mixture of science and philosophy, the book will appeal to scientists and advanced students of microbiology, evolution and ecology alike.