Microbial Zoonoses And Sapronoses

This book presents the state of art in the field of microbial zoonoses and sapronoses. It could be used as a textbook or manual in microbiology and medical zoology for students of human and veterinary medicine, including Ph.D. students, and for biomedicine scientists and medical practitioners and specialists as well. Surprisingly, severe zoonoses and sapronoses still appear that are either entirely new (e.g., SARS), newly recognized (Lyme borreliosis), resurging (West Nile fever in Europe), increasing in incidence (campylobacterosis), spatially expanding (West Nile fever in the Americas), with a changing range of hosts and/or vectors, with changing clinical manifestations or acquiring antibiotic resistance. The collective term for those diseases is (re)emerging infections, and most of them represent zoonoses and sapronoses (the rest are anthroponoses). The number of known zoonotic and sapronotic pathogens of humans is continually growing − over 800 today. In the introductory part, short characteristics are given of infectious and epidemic process, including the role of environmental factors, possibilities of their epidemiological surveillance, and control. Much emphasis is laid on ecological aspects of these diseases (haematophagous vectors and their life history; vertebrate hosts of zoonoses; habitats of the agents and their geographic distribution; natural focality of diseases). Particular zoonoses and sapronoses are then characterized in the following brief paragraphs: source of human infection; animal disease; transmission mode; human disease; epidemiology; diagnostics; therapy; geographic distribution.

This textbook, which is the first volume in the series Microbial Zoonoses, provides a comprehensive overview of the diagnosis, treatment and control of zoonotic parasitic diseases. The book is divided into two sections; the first section discusses the classification of parasitic zoonoses and includes general information on the diagnosis, treatment, epidemiology, prevention, and control of parasitic zoonoses. It also describes the biological features of these organisms, host-parasite interactions, and the disease spectrum, as well as the importance of public health control measures, such as surveillance, and prophylactic measures in controlling these diseases.The second section explores the important zoonotic diseases caused by ectoparasites, protozoan and helminths parasites. It also reviews the life cycle, pathogenesis, pathology, immunology and clinical manifestations, modern diagnostic methods, treatment regimen, prevention, control, and epidemiology of these parasites.Cutting across the disciplines, this book serves as a guide to postgraduate students, faculty members, public health experts, and medical administrators who are interested in the management of these parasitic zoonotic infections.

Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk—no matter how small—must be considered, assessed, and properly mitigated. If the science isn't safe, it isn't good. Now in its fifth edition, Biological safety: Principles and Practices remains the most comprehensive biosafety reference. Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom. Specifically, Biological Safety covers protection and control elements—from biosafety level cabinets and personal protection systems to strategies and decontamination methods administrative concerns in biorisk management, including regulations, guidelines, and compliance various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.

This book provides comprehensive knowledge on diseases in livestock that are caused by viruses, parasites and bacteria. Emerging and re-emerging pathogens are presented in detail for various animal groups and in-depth insights into pathogenesis and epidemiology will be provided for each of them. In addition, state-of-the-art treatment possibilities, control measures as well as vaccination strategies are discussed. The recent years have witnessed a sharp increase in the number of emerging and re-emerging infectious diseases of livestock and many of these, including Influenza, Corona and Hanta are of public health importance. The reasons for this development are manifold:changes in the climate, life cycle of vectors and increased global travel. Also, due to extensive deforestation, livestock are increasingly coming in direct contact with wild animals that are reservoirs of many emerging pathogens. Recent progress in diagnosis and management of emerging infectious diseases are also topic of this book.

This book offers an accessible and up-to-date reference on primate zoonoses. Recent years have witnessed a rise in human diseases zoonotically transferred from animals, with wild primates implicated in the spread of numerous newly emerging infections. The authors go beyond simply providing an inventory of diseases, helping readers to understand how and why they are transmitted. Important consideration is given to the contemporary cultural and ecological factors involved.

The second half of the 20th century and the beginning of the 21st century witnessed important changes in ecology, climate and human behaviour that favoured the development of urban pests. Most alarmingly, urban planners now face the dramatic expansion of urban sprawl, in which city suburbs are growing into the natural habitats of ticks, rodents and other pests. Also, many city managers now erroneously assume that pest-borne diseases are relics of the past. All these changes make timely a new analysis of the direct and indirect effects of present-day urban pests on health. Such an analysis should lead to the development of strategies to manage them and reduce the risk of exposure. To this end, WHO invited international experts in various fields - pests, pest-related diseases and pest management - to provide evidence on which to base policies. These experts identified the public health risk posed by various pests and appropriate measures to prevent and control them. This book presents their conclusions and formulates policy options for all levels of decision-making to manage pests and pest-related diseases in the future. [Ed.]

Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.

The book begins with a review of zoonotic pandemics of the past: the “Black Death” or bubonic plague of the Middle Ages, the Spanish Influenza pandemic (derived from avian influenza) of the early 20th century, to the more modern pandemic of AIDS/HIV infection, which originated in Africa from primates. However, the majority of chapters focus on more recent zoonoses, which have been recognized since the late 20th century to the present: · SARS and MERS coronaviruses· New avian influenza viruses · The tick-borne Henan fever virus from China· The tick-borne Heartland virus from the United States · Recently recognized bacterial pathogens, such as Streptococcus suis from pigs. In addition, reemergence of established zoonoses that have expanded their niche are reviewed, such as the spread of Zika virus and Chikungunya virus to the Western Hemisphere, and the emergence and spread of Ebola virus infection in Africa. A chapter is also devoted to an overview of the mechanisms and various types of animals involved in the transmission of diseases to humans, and the potential means of control and prevention. Many endemic and sporadic diseases are still transmitted by animals, through either direct or indirect contact, and zoonoses are estimated to account for about 75% of all new and emerging infectious diseases. It is predicted by public health experts that the next major pandemic of infectious disease will be of animal origin, making Emerging Zoonoses: A Worldwide Perspective a crucial resource to all health care specialists by providing them with much needed information on these zoonotic diseases.iv>