Micromachines For Biological Micromanipulation

This book provides an overview of the noteworthy developments in the field of micromachining, with a specific focus on microinjection systems used for biological micromanipulation. The author also explores the design, development, and fabrication of new mechanical designs for micromachines, with plenty of examples that elucidate their modeling and control. The design and fabrication of a piezoelectric microinjector, constant force microinjector, constant force microgripper, PDVF microforce sensor, and a piezoelectric microsyringe are presented as examples of new technology for microinjection systems. This book is appropriate for both researchers and advanced students in bioengineering.

Robotics for Cell Manipulation and Characterization provides fundamental principles underpinning robotic cell manipulation and characterization, state-of-the-art technical advances in micro/nano robotics, new discoveries of cell biology enabled by robotic systems, and their applications in clinical diagnosis and treatment. This book covers several areas, including robotics, control, computer vision, biomedical engineering and life sciences using understandable figures and tables to enhance readers’ comprehension and pinpoint challenges and opportunities for biological and biomedical research. Focuses on, and comprehensively covers, robotics for cell manipulation and characterization Highlights recent advances in cell biology and disease treatment enabled by robotic cell manipulation and characterization Provides insightful outlooks on future challenges and opportunities

Mechanical Design of Piezoelectric Energy Harvesters: Generating Electricity from Human Walking provides the state-of-the-art, recent mechanical designs of piezoelectric energy harvesters based on piezoelectric stacks. The book discusses innovative mechanism designs for energy harvesting from multidimensional force excitation, such as human walking, which offers higher energy density. Coverage includes analytical modeling, optimal design, simulation study, prototype fabrication, and experimental investigation. Detailed examples of their analyses and implementations are provided. The book's authors provide a unique perspective on this field, primarily focusing on novel designs for PZT Energy harvesting in biomedical engineering as well as in integrated multi-stage force amplification frame. This book presents force-amplification compliant mechanism design and force direction-transmission mechanism design. It explores new mechanism design approaches using piezoelectric materials and permanent magnets. Readers can expect to learn how to design new mechanisms to realize multidimensional energy harvesting systems. Provides new mechanical designs of piezoelectric energy harvesters for multidimensional force excitation Contains both theoretical and experimental results Fully supported with real-life examples on design, modeling and implementation of piezoelectric energy harvesting devices

Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies. Comprehensive coverage of micro and nano-system technology and application to biophysical studies of cells and small organisms. Highlights the most recent advances in cellular and organismal biophysics enabled by micro and nano systems. Insightful outlook on future directions and trends in each chapter covering a sub-area of the book topic.

In Light Driven Micromachines, the fundamental principles and unique characteristics of light driven material structures, simple mechanisms and integrated machines are explored. Very small light driven systems provide a number of interesting features and unique design opportunities because streams of photons deliver energy into the system and provide the control signal used to regulate the response of the micron sized device. Through innovative material design and clever component fabrication, these optically powered tiny machines can be created to perform mechanical work when exposed to varying light intensity, wavelength, phase, and/or polarization. The book begins with the scientific background necessary to understand the nature of light and how light can initiate physical movement by inducing material deformation or altering the surrounding environment to impose micro-forces on the actuating mechanisms. The impact of physical size on the performance of light driven mechanisms and machines is discussed, and the nature of light–material interactions is reviewed. These interactions enable very small objects and mechanical components to be trapped and manipulated by a focused light beam, or produce local temperature gradients that force certain materials to undergo shape transformation. Advanced phase transition gels, polymers, carbon-based films and piezoelectric ceramics that exhibit direct light-to-mechanical energy conversion are examined from the perspective of designing optically driven actuators and mechanical systems. The ability of light to create photothermal effects that drive microfluidic processes and initiate the phase transformation of temperature sensitive shape memory materials are also explored in the book. This compendium seeks to inspire the next generation of scientists and engineers by presenting the fundamental principles of this emerging interdisciplinary technology and exploring how the properties of light can be exploited for microfluidic, microrobotic, biomedical and space applications.

Force and Position Control of Mechatronic Systems provides an overview of the general concepts and technologies in the area of force and position control. Novel ideas and innovations related to this area are presented and reported in detail, and examples of applications in medical technology are given. The book begins by introducing force sensing, and modelling of contacting objects. In then moves steadily through a variety of topics, including: • disturbance observer-based force estimation; • force-based supervisory control; • stabilization systems; • controller design; and • control of tube insertion procedures. This book will be of interest to researchers, engineers and students interested in force control, particularly those with a focus on medical applications of these ideas. Advances in Industrial Control reports and encourages the transfer of technology in control engineering. The rapid development of control technology has an impact on all areas of the control discipline. The series offers an opportunity for researchers to present an extended exposition of new work in all aspects of industrial control.

The volume set LNAI 11740 until LNAI 11745 constitutes the proceedings of the 12th International Conference on Intelligent Robotics and Applications, ICIRA 2019, held in Shenyang, China, in August 2019. The total of 378 full and 25 short papers presented in these proceedings was carefully reviewed and selected from 522 submissions. The papers are organized in topical sections as follows: Part I: collective and social robots; human biomechanics and human-centered robotics; robotics for cell manipulation and characterization; field robots; compliant mechanisms; robotic grasping and manipulation with incomplete information and strong disturbance; human-centered robotics; development of high-performance joint drive for robots; modular robots and other mechatronic systems; compliant manipulation learning and control for lightweight robot. Part II: power-assisted system and control; bio-inspired wall climbing robot; underwater acoustic and optical signal processing for environmental cognition; piezoelectric actuators and micro-nano manipulations; robot vision and scene understanding; visual and motional learning in robotics; signal processing and underwater bionic robots; soft locomotion robot; teleoperation robot; autonomous control of unmanned aircraft systems. Part III: marine bio-inspired robotics and soft robotics: materials, mechanisms, modelling, and control; robot intelligence technologies and system integration; continuum mechanisms and robots; unmanned underwater vehicles; intelligent robots for environment detection or fine manipulation; parallel robotics; human-robot collaboration; swarm intelligence and multi-robot cooperation; adaptive and learning control system; wearable and assistive devices and robots for healthcare; nonlinear systems and control. Part IV: swarm intelligence unmanned system; computational intelligence inspired robot navigation and SLAM; fuzzy modelling for automation, control, and robotics; development of ultra-thin-film, flexible sensors, and tactile sensation; robotic technology for deep space exploration; wearable sensing based limb motor function rehabilitation; pattern recognition and machine learning; navigation/localization. Part V: robot legged locomotion; advanced measurement and machine vision system; man-machine interactions; fault detection, testing and diagnosis; estimation and identification; mobile robots and intelligent autonomous systems; robotic vision, recognition and reconstruction; robot mechanism and design. Part VI: robot motion analysis and planning; robot design, development and control; medical robot; robot intelligence, learning and linguistics; motion control; computer integrated manufacturing; robot cooperation; virtual and augmented reality; education in mechatronics engineering; robotic drilling and sampling technology; automotive systems; mechatronics in energy systems; human-robot interaction.