Moda 8 Advances In Model Oriented Design And Analysis

This volume contains the proceedings of the 8th Workshop on Model-Oriented Design and Analysis. It offers leading and pioneering work on optimal experimental designs, both from a mathematical/statistical point of view and with regard to real applications. Scientists from all over the world have contributed to this volume. Primary topics are designs for nonlinear models and applications to experimental medicine.

This volume contains pioneering contributions to both the theory and practice of optimal experimental design. Topics include the optimality of designs in linear and nonlinear models, as well as designs for correlated observations and for sequential experimentation. There is an emphasis on applications to medicine, in particular, to the design of clinical trials. Scientists from Europe, the US, Asia, Australia and Africa contributed to this volume of papers from the 11th Workshop on Model Oriented Design and Analysis.

This book collects the proceedings of the 10th Workshop on Model-Oriented Design and Analysis (mODa). A model-oriented view on the design of experiments, which is the unifying theme of all mODa meetings, assumes some knowledge of the form of the data-generating process and naturally leads to the so-called optimum experimental design. Its theory and practice have since become important in many scientific and technological fields, ranging from optimal designs for dynamic models in pharmacological research, to designs for industrial experimentation, to designs for simulation experiments in environmental risk management, to name but a few. The methodology has become even more important in recent years because of the increased speed of scientific developments, the complexity of the systems currently under investigation and the mounting pressure on businesses, industries and scientific researchers to reduce product and process development times. This increased competition requires ever increasing efficiency in experimentation, thus necessitating new statistical designs. This book presents a rich collection of carefully selected contributions ranging from statistical methodology to emerging applications. It primarily aims to provide an overview of recent advances and challenges in the field, especially in the context of new formulations, methods and state-of-the-art algorithms. The topics included in this volume will be of interest to all scientists and engineers and statisticians who conduct experiments.

Statisticians and experimentalists will find the latest trends in optimal experimental design research. Some papers are pioneering contributions, leading to new open research problems. It is a colection of peer reviewed papers.

The volume contains the proceedings of the 7th Workshop on Model-Oriented Design and Analysis which has had the purpose of bringing together leading researchers in Eastern and Western Europe for an in-depth discussion of the optimal design of experiments. The papers are representative of the latest developments concerning non-linear models, computational algorithms and important applications, especially to medical statistics.

The volume contains the proceedings of the 7th Workshop on Model-Oriented Design and Analysis which has had the purpose of bringing together leading researchers in Eastern and Western Europe for an in-depth discussion of the optimal design of experiments. The papers are representative of the latest developments concerning non-linear models, computational algorithms and important applications, especially to medical statistics.

This book includes many of the papers presented at the 6th International workshop on Model Oriented Data Analysis held in June 2001. This series began in March 1987 with a meeting on the Wartburg near Eisenach (at that time in the GDR). The next four meetings were in 1990 (St Kyrik monastery, Bulgaria), 1992 (Petrodvorets, St Petersburg, Russia), 1995 (Spetses, Greece) and 1998 (Marseilles, France). Initially the main purpose of these workshops was to bring together leading scientists from 'Eastern' and 'Western' Europe for the exchange of ideas in theoretical and applied statistics, with special emphasis on experimental design. Now that the sep aration between East and West is much less rigid, this exchange has, in principle, become much easier. However, it is still important to provide opportunities for this interaction. MODA meetings are celebrated for their friendly atmosphere. Indeed, dis cussions between young and senior scientists at these meetings have resulted in several fruitful long-term collaborations. This intellectually stimulating atmosphere is achieved by limiting the number of participants to around eighty, by the choice of a location in which communal living is encour aged and, of course, through the careful scientific direction provided by the Programme Committee. It is a tradition of these meetings to provide low cost accommodation, low fees and financial support for the travel of young and Eastern participants. This is only possible through the help of sponsors and outside financial support was again important for the success of the meeting.