Modeling The Heart And The Circulatory System

The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.

The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.

The book “Mechatronics: Recent Technological and Scientific Advances” provides comprehensive and accessible coverage of the evolving disciplines of mechatronics for nanotechnology, automatic control & robotics, biomedical engineering, design manufacturing and testing of MEMS, metrology, photonics, mechatronic products majors. It is already the third volume following the previous editions in 2007 and 2009 providing a recent state of advances in mechatronics presented on the 9th International Conference Mechatronics 2011, hosted this year at the Faculty of Mechatronics, Warsaw University of Technology, Poland. The carefully selected contributions give an insight into the current development of these scientific disciplines, present the new results of research and development and indicate the trends of development in the interdisciplinary field of mechatronics systems. Even though many people believe that the presence of mechanical, electrical, electronic components, and computers make a system mechatronics, others do not feel the same as there is nothing wrong with the individual identity. The enclosed material is original, and reflects the main research tendencies and developments in mechatronics among Mechatronics 2011 contributing countries. It helps to acquire the mix of skills needed to comprehend and design mechatronic systems and also provides with the frame of understanding to develop a truly interdisciplinary and integrated approach to engineering. The enclosed material is original, and reflects the main research tendencies and developments in mechatronics among Mechatronics 2011 contributing countries. It helps to acquire the mix of skills needed to comprehend and design mechatronic systems and also provides with the frame of understanding to develop a truly interdisciplinary and integrated approach to engineering.

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Addresses the mathematical and numerical modelling of the human cardiovascular system, from patient data to clinical applications.

Mathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.

This extensively revised second edition traces the development of the basic concepts in cardiovascular physiology in light of the accumulated experimental and clinical evidence. It considers the early embryonic circulation, where blood circulation suggests the existence of a motive force, tightly coupled to the metabolic demands of the tissues. It proposes that rather than being an organ of propulsion, the heart, serves as an organ of control, generating pressure by rhythmically impeding blood flow. New and expanded chapters cover the arterial pulse, circulation in the upright posture, microcirculation and functional heart morphology. Heart and Circulation offers a new perspective for deeper understanding of the human cardiovascular system. It is therefore a thought-provoking resource for cardiologists, cardiac surgeons and trainees interested in models of human circulation.