Modern Statistics For The Life Sciences

Model formulae represent a powerful methodology for describing, discussing, understanding, and performing that large part of statistical tests known as linear statistics. The book aims to put this methodology firmly within the grasp of undergraduates.

Statistics for the Life Sciences, Fourth Edition, is the perfect book for introductory statistics classes, covering the key concepts of statistics as applied to the life sciences, while incorporating the tools and themes of modern data analysis. This text uses an abundance of real data in the exercises and examples to minimize computation, so that students can focus on the statistical concepts and issues, not the mathematics. Basic algebra is assumed as a prerequisite. ¿ This latest edition is also available as an enhanced Pearson eText. This exciting new version features an embedded versio.

This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.

Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics, beyond just a simple application of statistics, is a confluence of statistics and knowledge of multiple intertwined fields. The application demands, the advancements in computer technology, and the rapid growth of life science data (e.g., genomics data) have promoted the formation of modern biostatistics. There are at least three characteristics of modern biostatistics: (1) in-depth engagement in the application fields that require penetration of knowledge across several fields, (2) high-level complexity of data because they are longitudinal, incomplete, or latent because they are heterogeneous due to a mixture of data or experiment types, because of high-dimensionality, which may make meaningful reduction impossible, or because of extremely small or large size; and (3) dynamics, the speed of development in methodology and analyses, has to match the fast growth of data with a constantly changing face. This book is written for researchers, biostatisticians/statisticians, and scientists who are interested in quantitative analyses. The goal is to introduce modern methods in biostatistics and help researchers and students quickly grasp key concepts and methods. Many methods can solve the same problem and many problems can be solved by the same method, which becomes apparent when those topics are discussed in this single volume.

The past decades have transformed the world of statistical data analysis, with new methods, new types of data, and new computational tools. The aim of Modern Statistics with R is to introduce you to key parts of the modern statistical toolkit. It teaches you: - Data wrangling - importing, formatting, reshaping, merging, and filtering data in R. - Exploratory data analysis - using visualisation and multivariate techniques to explore datasets. - Statistical inference - modern methods for testing hypotheses and computing confidence intervals. - Predictive modelling - regression models and machine learning methods for prediction, classification, and forecasting. - Simulation - using simulation techniques for sample size computations and evaluations of statistical methods. - Ethics in statistics - ethical issues and good statistical practice. - R programming - writing code that is fast, readable, and free from bugs. Starting from the very basics, Modern Statistics with R helps you learn R by working with R. Topics covered range from plotting data and writing simple R code to using cross-validation for evaluating complex predictive models and using simulation for sample size determination. The book includes more than 200 exercises with fully worked solutions. Some familiarity with basic statistical concepts, such as linear regression, is assumed. No previous programming experience is needed.

Appropriate for all courses in statistical methods for the agricultural, life, health, and environmental sciences, this book offers a practical and modern approach that minimizes computation and emphasizes conceptual understanding. Rao continually emphasizes issues and topics most relevant to modern day research in the life sciences. For example, point and interval estimation take priority over testing of statistical hypothesis and methods and guidelines for determination of sample size are indicated whenever possible. Statistical Research Methods in the Life Sciences also presents a self-contained and complete discussion of each experimental situation considered. In the two-sample setting, for example, in addition to presenting the procedures under the usual analysis of variance assumption, Rao also presents methods for checking the validity of the assumptions.