Molecular Vaccines
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Molecular Vaccines
Author | : Matthias Giese |
Publsiher | : Springer Science & Business Media |
Total Pages | : 423 |
Release | : 2013-11-08 |
Genre | : Medical |
ISBN | : 9783319009780 |
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This title discusses all aspects of non-infectious and non-cancer– so called NINC – vaccines. Hypertension, diabetes and allergy vaccine development are referred to as well as the use of adjuvants and nanotechnology in vaccine development. The way of novel vaccines from bench to preclinical to clinical studies and launch to the market under EMEA (European Medicines Agency) and FDA (Food and Drug Administration) guidelines are described in-depth. The book is therefore of interest for researchers and clinicians engaged in vaccine development and molecular vaccine application.
Molecular Vaccines
Author | : Matthias Giese |
Publsiher | : Springer Science & Business Media |
Total Pages | : 447 |
Release | : 2013-10-16 |
Genre | : Medical |
ISBN | : 9783709114193 |
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This book gives a comprehensive overview to all aspects of global molecular vaccine research. It introduces concepts of vaccine immunology and molecular vaccine development for viral, bacterial, parasitic and fungal infections. Furthermore, the broad field of research and development in molecular cancer vaccines is discussed in detail. This book is a must have for scientists and clinicians interested in new developments in molecular vaccine research and application in infections and cancer.
Introduction to Molecular Vaccinology
Author | : Matthias Giese |
Publsiher | : Springer |
Total Pages | : 373 |
Release | : 2016-03-11 |
Genre | : Medical |
ISBN | : 9783319258324 |
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This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development.
Adverse Effects of Vaccines
Author | : Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review Adverse Effects of Vaccines |
Publsiher | : National Academies Press |
Total Pages | : 894 |
Release | : 2012-04-26 |
Genre | : Medical |
ISBN | : 9780309214353 |
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In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
Opportunities in Biotechnology for Future Army Applications
Author | : National Research Council,Division on Engineering and Physical Sciences,Board on Army Science and Technology,Committee on Opportunities in Biotechnology for Future Army Applications |
Publsiher | : National Academies Press |
Total Pages | : 118 |
Release | : 2001-07-11 |
Genre | : Science |
ISBN | : 9780309075558 |
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This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.
Molecular Vaccines against Pathogens in the Post Genomic Era
Author | : Angel Alejandro Oñate,Alberto Moreno,Yanmin Wan |
Publsiher | : Frontiers Media SA |
Total Pages | : 158 |
Release | : 2020-02-27 |
Genre | : Electronic Book |
ISBN | : 9782889635139 |
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Modern Approaches to Vaccines
Author | : Robert M. Chanock,Richard Alan Lerner |
Publsiher | : Unknown |
Total Pages | : 132 |
Release | : 1984 |
Genre | : Genes, Viral |
ISBN | : UCAL:B4486097 |
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DNA Vaccines
Author | : Mark W. Saltzman,Hong Shen,Janet L. Brandsma |
Publsiher | : Springer Science & Business Media |
Total Pages | : 382 |
Release | : 2008-02-02 |
Genre | : Medical |
ISBN | : 9781597451680 |
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In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA delivered by DNA vaccination (as this approach is called) (2,3). The appe- ance of this new vaccination strategy coincided with advances in molecular biology, which provided new tools to study and manipulate the basic elements of an organism’s genome and also could also be applied to the design and production of DNA vaccines. DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control. Consistent with the approach of the Methods in Molecular Medicine series, these chapters contain detailed practical procedures on the latest DNA vaccine technology. The enthusiasm for DNA vaccine technology is made clear by the number of research studies published on this topic since the mid-1990s.