Multimodal Imaging In Neurology

The field of brain imaging is developing at a rapid pace and has greatly advanced the areas of cognitive and clinical neuroscience. The availability of neuroimaging techniques, especially magnetic resonance imaging (MRI), functional MRI (fMRI), diffusion tensor imaging (DTI) and magnetoencephalography (MEG) and magnetic source imaging (MSI) has brought about breakthroughs in neuroscience. To obtain comprehensive information about the activity of the human brain, different analytical approaches should be complemented. Thus, in "intermodal multimodality" imaging, great efforts have been made to combine the highest spatial resolution (MRI, fMRI) with the best temporal resolution (MEG or EEG). "Intramodal multimodality" imaging combines various functional MRI techniques (e.g., fMRI, DTI, and/or morphometric/volumetric analysis). The multimodal approach is conceptually based on the combination of different noninvasive functional neuroimaging tools, their registration and cointegration. In particular, the combination of imaging applications that map different functional systems is useful, such as fMRI as a technique for the localization of cortical function and DTI as a technique for mapping of white matter fiber bundles or tracts. This booklet gives an insight into the wide field of multimodal imaging with respect to concepts, data acquisition, and postprocessing. Examples for intermodal and intramodal multimodality imaging are also demonstrated.

The field of brain imaging is developing at a rapid pace and has greatly advanced the areas of cognitive and clinical neuroscience. The availability of neuroimaging techniques, especially magnetic resonance imaging (MRI), functional MRI (fMRI), diffusion tensor imaging (DTI) and magnetoencephalography (MEG) and magnetic source imaging (MSI) has brought about breakthroughs in neuroscience. To obtain comprehensive information about the activity of the human brain, different analytical approaches should be complemented. Thus, in "intermodalmultimodality" imaging, great efforts have been made to combine the highest spatial resolution (MRI, fMRI) with the best temporal resolution (MEG or EEG). "Intramodal multimodality" imaging combines various functional MRI techniques (e.g., fMRI, DTI, and/or morphometric/volumetric analysis). Themultimodal approach is conceptually based on the combination of different noninvasive functional neuroimaging tools, their registration and cointegration. In particular, the combination of imaging applications that map different functional systems is useful, such as fMRI as a technique for the localization of cortical function and DTI as a technique for mapping of white matter fiber bundles/tracts. This booklet gives an insight into the wide field of multimodal imaging with respect to concepts, data acquisition, and postprocessing. Examples for intermodal and intramodal multimodality imaging are also demonstrated.

In vivo brain neuroimaging with cutting-edge technologies has achieved great success with high spatial and temporal resolutions. Several distinct medical imaging perspectives such as disease neurobiology, multimodal imaging techniques and applications, large-size clinical trials of neuro-oncology, and bioinformatics with illustrative examples and comprehensive summaries could expand our knowledge of neuroimaging mechanism, methodologies, and applications. This book highlights the possibility and achievement of early detection and multiple neuroimaging biomarkers based on various features for pathophysiological probing and therapeutic prevention. It examines the use of neuroimaging techniques such as magnetic resonance imaging (MRI), electroencephalography (EEG), and near-infrared resonance spectroscopy (NIRS) with specific and innovative biomedical applications. It provides thorough reviews, accurate descriptions, and confirmative evidences of many related important research topics together with up-to-date imaging network management.

This book provides an accessible and comprehensive overview of the state of the art in multimodal, multiparametric preclinical imaging, covering all the modalities used in preclinical research. The role of different combinations of PET, CT, MR, optical, and optoacoustic imaging methods is examined and explained for a range of applications, from research in oncology, neurology, and cardiology to drug development. Examples of animal studies are highlighted in which multimodal imaging has been pivotal in delivering otherwise unobtainable information. Hardware and software image registration methods and animal-specific factors are also discussed. The readily understandable text is enhanced by numerous informative illustrations that help the reader to appreciate the similarities to, but also the differences from, clinical applications. Image Fusion in Preclinical Applications will be of interest to all who wish to learn more about the use of multimodal/multiparametric imaging as a tool for in vivo investigations in preclinical medical and pharmaceutical research.

The field of brain imaging is developing at a rapid pace and has greatly advanced the areas of cognitive and clinical neuroscience. The availability of neuroimaging techniques, especially magnetic resonance imaging (MRI), functional MRI (fMRI), diffusion tensor imaging (DTI) and magnetoencephalography (MEG) and magnetic source imaging (MSI) has brought about breakthroughs in neuroscience. To obtain comprehensive information about the activity of the human brain, different analytical approaches should be complemented. Thus, in "intermodal multimodality" imaging, great efforts have been made to combine the highest spatial resolution (MRI, fMRI) with the best temporal resolution (MEG or EEG). "Intramodal multimodality" imaging combines various functional MRI techniques (e.g., fMRI, DTI, and/or morphometric/volumetric analysis). The multimodal approach is conceptually based on the combination of different noninvasive functional neuroimaging tools, their registration and cointegration. In particular, the combination of imaging applications that map different functional systems is useful, such as fMRI as a technique for the localization of cortical function and DTI as a technique for mapping of white matter fiber bundles or tracts. This booklet gives an insight into the wide field of multimodal imaging with respect to concepts, data acquisition, and postprocessing. Examples for intermodal and intramodal multimodality imaging are also demonstrated. Table of Contents: Introduction / Neurological Measurement Techniques and First Steps of Postprocessing / Coordinate Transformation / Examples for Multimodal Imaging / Clinical Aspects of Multimodal Imaging / References / Biography

If a picture is worth a thousand words, then dynamic images of brain activity certainly warrant many, many more. This book will help users learn to decipher the dynamic imaging data that will be critical to our future understanding of complex brain functions. In recent years, there have been unprecedented methodological advancements in the imaging of brain activity. These techniques allow the measurement of everything from neural activity (e.g., membrane potential, ion ?ux, neurotransmitter ?ux) to energy metabolism (e.g., glucose consumption, oxygen consumption, creatine kinase ?ux) and functional hyperemia (e.g., blood ?ow, volume, oxygenation). This book deals with a variety of magnetic resonance, electrophysiology, and optical methods that are often used to measure some of these dynamic processes. All chapters were written by leading experts, spanning three continents, specializing in state-of-the-art methods. Brie?y, the book has ?ve sections. In the introductory section, there are two chapters; the ?rst one contains a brief pre- ble to dynamic brain imaging and the other presents a novel, analytical approach to processing of dynamically acquired data. The second section has four chapters and delves into a wide range of optical imaging methods. I am privileged to include a chapter from Lawrence B. Cohen, considered by many to be the authority on optical imaging and spectroscopy, both in vitro and in vivo [Cohen LB (1973) Physiol Rev.

Neuroradiology is evolving at a pace far quicker than any other specialty. It's important for specialists to have detailed knowledge of the newest advances, including state-of-the-art imaging techniques. In this abundantly illustrated text, you'll find the latest information on diseases, imaging principles, differential diagnosis, treatment strategies, and much more! This book is designed to help you easily apply theoretical concepts to your daily practice. It offers a clear and concise review of the most important neuroradiologic approaches to a variety of disorders. Key points are highlighted throughout the text, providing rapid access to the information you need. Residents and experienced practitioners alike will benefit from the wealth of information this book provides. Key benefits: Up-to-the-minute analysis on the newest imaging techniques Detailed review of the use of MRI to measure brain maturation Extensively illustrated to enhance understanding of difficult concepts Most important information is boxed and shaded for emphasis--ideal for board preparation An indispensable aid in clinical settings, NEURORADIOLOGY is an excellent guide to image interpretation as well as a valuable reference for residents preparing for the boards.

An accessible primer for courses on human neuroimaging methods, with example research studies, color figures, and practice questions.