Nanofluidics

In his celebrated lecture at the APS meeting in 1959, Richard Feynman pondered the potential of miniaturization in the physical sciences and proposed a variety of new nano-tools. Since then, many of these predictions have become reality including the development and application of nanofluidics. This timely book fills a gap in the current reference literature in this exciting and growing field and is dedicated to the field of nanofluidics with a focus on bioanalytical applications. These nanoscale analytical instruments employ micromachined features and are able to manipulate fluid samples with high precision and efficiency. The book is written at a level accessible to experts and non-experts alike and is essential reading for all advanced nanobiotechnology courses within academic institutions.

Taking you to the forefront of the emerging field of Nanofluidics, this cutting-edge book details the physics and applications of fluid flow in nanometer scale channels. You gain a solid understanding of the fundamental aspects of transport processes and force interactions in microscale. Moreover, this unique resource presents the latest research on nanoscale transport phenomena. You find a comprehensive overview of fabrication technologies for nanotechnologies, including detailed technology recipes and parameters. The book concludes with a look at future trends and the possible directions this new field could take.

This book provides an introduction to nanofluidics in a simple manner and can be easily followed by senior undergraduate students, graduate students, and other researchers who have some background in fluid mechanics. The book covers the main topics about the fundamentals of nanofluidics and how it differs from classic fluid mechanics. It also describes the methodologies of nanofluidics, including numerical approaches, e.g., molecular dynamics simulation and experimental techniques. Fundamental physics and new phenomena in nanofluidics are the major concerns of this book. The author goes on to discuss nanocofinements and the parameters that affect the fluid dynamics at the nanoscale and make flow analysis complex. These parameters accommodate rich, new flow phenomena that may not be observed at the macro- and microscale. Although not all of the new phenomena will find widespread applications, the physics underlying these new phenomena may offer insights for other fields. This is one of the reasons why this book emphasizes the mechanisms of various flow fashions. Explores the unique characteristics of nanoscale flows and related properties Reviews the latest research of nanoscale ion transport and its applications Discusses the fluid flows in nanoconfinements in a unique manner based on the author's original research Incorporates important applications of nanofluidics throughout.

This book provides an introduction to nanofluidics in a simple manner and can be easily followed by senior undergraduate students, graduate students, and other researchers who have some background in fluid mechanics. The book covers the main topics about the fundamentals of nanofluidics and how it differs from classic fluid mechanics. It also describes the methodologies of nanofluidics, including numerical approaches, e.g., molecular dynamics simulation and experimental techniques. Fundamental physics and new phenomena in nanofluidics are the major concerns of this book. The author goes on to discuss nanocofinements and the parameters that affect the fluid dynamics at the nanoscale and make flow analysis complex. These parameters accommodate rich, new flow phenomena that may not be observed at the macro- and microscale. Although not all of the new phenomena will find widespread applications, the physics underlying these new phenomena may offer insights for other fields. This is one of the reasons why this book emphasizes the mechanisms of various flow fashions. Explores the unique characteristics of nanoscale flows and related properties Reviews the latest research of nanoscale ion transport and its applications Discusses the fluid flows in nanoconfinements in a unique manner based on the author's original research Incorporates important applications of nanofluidics throughout.

There has been significant growth in the field of nanofluidics, where nanoscale analytical instruments employ micromachined features and are able to manipulate fluid samples with high precision and efficiency and have many advantages over their conventional (larger) analogues. The new edition of Nanofluidics has been fully revised and updated with the latest advancements and applications. With a focus on bioanalysis, specific applications are given with case studies. The end of each chapter now also features a methodology section to explain experimental protocols and “tips and tricks”. The editors draw on an international authorship and provide a handbook for the community. Written at an accessible level the book is suitable for both experts and non-experts alike.

In the present book, various applications of microfluidics and nanofluidics are introduced. Microfluidics and nanofluidics span a broad array of disciplines including mechanical, materials, and electrical engineering, surface science, chemistry, physics and biology. Also, this book deals with transport and interactions of colloidal particles and biomolecules in microchannels, which have great importance to many microfluidic applications, such as drug delivery in life science, microchannel heat exchangers in electronic cooling, and food processing industry. Furthermore, this book focuses on a detailed description of the thermal transport behavior, challenges and implications that involve the development and use of HTFs under the influence of atomistic-scale structures and industrial applications.

To provide an interdisciplinary readership with the necessary toolkit to work with micro- and nanofluidics, this book provides basic theory, fundamentals of microfabrication, advanced fabrication methods, device characterization methods and detailed examples of applications of nanofluidics devices and systems. Case studies describing fabrication of complex micro- and nanoscale systems help the reader gain a practical understanding of developing and fabricating such systems. The resulting work covers the fundamentals, processes and applied challenges of functional engineered nanofluidic systems for a variety of different applications, including discussions of lab-on-chip, bio-related applications and emerging technologies for energy and environmental engineering. The fundamentals of micro- and nanofluidic systems and micro- and nanofabrication techniques provide readers from a variety of academic backgrounds with the understanding required to develop new systems and applications. Case studies introduce and illustrate state-of-the-art applications across areas, including lab-on-chip, energy and bio-based applications. Prakash and Yeom provide readers with an essential toolkit to take micro- and nanofluidic applications out of the research lab and into commercial and laboratory applications.

This book reviews the latest advancement of microfluidics and nanofluidics with a focus on electrokinetic phenomena in microfluidics and nanofluidics. It provides fundamental understanding of several new interfacial electrokinetic phenomena in microfluidics and nanofluidics. Chapter 1 gives a brief review of the fundamentals of interfacial electrokinetics. Chapter 2 shows induced charge electrokinetic transport phenomena. Chapter 3 presents the new advancement in DC dielectrophoresis. Chapter 4 introduces a novel nanofabrication method and the systematic studies of electrokinetic nanofluidics. Chapter 5 presents electrokinetic phenomena associated with Janus particles and Janus droplets. Chapter 6 introduces a new direction of electrokinetic nanofluidics: nanofluidic iontronics. Chapter 7 discusses an important differential resistive pulse sensor in microfluidics and nanofluidics.