Nanorobotics And Nanodiagnostics In Integrative Biology And Biomedicine

Nanorobotics and Nanodiagnostics in Integrative Biology and Biomedicine "Nanorobotics and nanodiagnostics” can be defined as a new generation of biohybrid and nanorobotics that translate fundamental biological principles into engineering design rules, or integrative living components into synthetic structures to create biorobots and nanodiagnotics that perform like natural systems. Nanorobots or nanobots are structured of a nanoscale made of individual assemblies. They can be termed as intelligent systems manufactured with self-assembly strategies by chemical, physical and biological approaches. The nanorobot can determine the structure and enhance the adaptability to the environment in interdisciplinary tasks. "Nanorobotics and nanodiagnostics" is a new generation of biohybrid that translates fundamental biological principles into engineering design rules to create biorobots that perform like natural systems. These biorobotics and diagnostics can now perform various missions to be accomplished certain tasks in the research areas such as integrative biology and biomedicine. "Nanorobotics and Nanodiagnostics in Integrative Biology and Biomedicine" sheds light on a comprehensive overview of the multidisciplinary areas that explore nanotherapeutics and nanorobotic manipulation in biology and medicine. It provides up-to-date knowledge of the promising fields of integrative biology and biomedicine for nano-assisted biorobotics and diagnostics to detect and treat diseases that will enable new scientific discoveries. /div

Nanotechnology-based Sensors for Efficient Detection of Environmental Pollution discusses the use of nanotechnology to generate sensors capable of performing efficient detection of different types of environmental pollutants. Nanomaterial’s characteristics such as large surface area, good reactivity, and possibility to suffer chemical surface modification to recognize different types of molecules are useful, especially to perform the detection of specific environmental pollutants. Innovative and efficient ways to detect environmental pollution are urgently needed for sustainability and the nanotechnology field has an enormous potential to offer strategic solutions. Nanotechnology-based sensors offer an efficient way of detecting the presence of contaminants and determine its structure and chemical nature is by applying nanotechnology and/or nanobiotechnology. This book will contain 5 parts: the first one will be dedicated to exploring environmental pollution as a threat to life on Earth and main contaminants (inorganic, organic or pathogens) and the risk they represent to living beings. The second part will be dedicated to nanotechnology allowing pollutants’ detection covering a brief history of nanotechnology-based sensors, different types of nanotechnology-based sensor (optical, electrochemical, and magnetic), nanotechnology-based sensors’ design and fabrication and nano biosensors. The third part will be focused on important specific pollutants (pesticides, heavy metal, dyes, toxic gas, pharmaceutical waste, petroleum hydrocarbons, and pathogenic microbes) and their detection by nanotechnology-based sensors. The fourth part will be dedicated to important nanomaterials in nanotechnology-based sensors, exploring carbon-based and non-carbon-based material in nanoscale (graphene, carbon nanotubes, quantum dots, magnetic nanomaterials, non-magnetic nanoparticles) and also point-of-care sensors and functionalization to generate optimized nanotechnology-based sensors to pollutants’ detection. The fifth and last part of Nanotechnology-based Sensors for Efficient Detection of Environmental Pollution will address relevant practical aspects related to nanotechnology-based sensors, covering advantages and challenges, safety, economic and commercial aspects related to the field and also sustainability, highlighting green nanomaterials on nanotechnology-based sensors. Provides a comprehensive, multidisciplinary review of nanotechnology-based sensors Supplies readers extensive knowledge on detecting harmful pollutants in different environments using nanotechnology-based sensors Presents chapters dedicated to the detection of pollutants different from toxic gas and pharmaceutical products, such as pesticides, heavy metals, dyes, pathogens, and petroleum hydrocarbons Introduces information on pollutants and the threats they represent to living beings, nanotechnology-based sensor’s design and fabrication, a brief history of the field, and practical issues related to the field, such as economics, safety, and challenges

Nanotechnology for Abiotic Stress Tolerance and Management in Crop Plants reviews the most recent literature on the role of nanomaterials in achieving sustainability in crop production in stressful environments. This book explores the adverse conditions caused by abiotic stress to crop plants, and the methods by which these conditions can be potentially overcome through developments in nanoscience and nanotechnology. Abiotic stresses such as drought, salinity, temperature stress, excessive water, heavy metal stress, UV stress etc. are major factors which may adversely affect the growth, development, and yield of crops. While recent research for ways of overcoming the physiological and biochemical changes brought on by these stresses has focused on genetic engineering of plants, additional research continues into alternative strategies to develop stress tolerant crops, including the use of nanoscience and nanotechnology. Providing an in-depth summary of research on nanomaterials and nano-based devices for field monitoring of crops, this book will serve as an ideal reference for academics, professionals, researchers, and students working in the field of agriculture, nanotechnology, plant science, material science, and crop production. Presents advancements in our understanding of molecular and physiological interactions between nanoparticles and crop plants Includes figures and illustrations to help readers visualize and easily understand the role of nanomaterials Serves as an ideal reference for those studying smart nanomaterials, biosensors, and nanodevices for real-time plant stress measurement

This text book will bring together a mix of both internationally known and established senior scientists along side up and coming (but already accomplished) junior scientists that have varying expertise in fundamental and applied nanotechnology to biology and medicine.

This book comprehensively reviews the history of nanotechnology, and describes the physiochemical properties of various nanoparticles and their biomedical applications. Covering the biotoxicity of nanoparticles, their bio-distribution and release kinetics, and their role in diagnosis, pre-clinical drug discovery and disease prevention, it also examines the application of nanoscaffolds in tissue engineering and as cell culture templates. Further, the book discusses several fabrication methodologies for regenerative medicine, and explores nanotechnology-based stem cell therapeutics, including stem cell transfection, stem cell delivery, and stem cell expansion for promoting tissue regeneration. Lastly, it addresses the use of DNA barcoding technology from nanosamples for the detection, identification and validation of emerging pathogens, biodiversity and ancient remnants of living specimens, and highlights various strategies for the plant-mediated synthesis of nanoparticles. Given its scope, it is a valuable reference resource for graduate students and researchers interested in understanding the diverse range of biomedical applications of nanoparticles.

This book describes the substantial progress recently made in the development of micro and nanorobotic systems, utilizing magnetic, optical, acoustic, electrical, and other actuation fields. It covers several areas of micro and nanorobotics including robotics, materials science, and biomedical engineering. Field-Driven Micro and Nanorobots for Biology and Medicine provides readers with fundamental physics at the micro and nano scales, state-of-the-art technical advances in field-driven micro and nanorobots, and applications in biological and biomedical disciplines.

Gene therapy is emerging as a new class of therapeutics for the treatment of inherited and acquired diseases. However, poor cellular uptake and instability of DNA in the physiological milieu limits its therapeutic potential, hence a vector which can protect and efficiently transport DNA to the target cells must be developed. Nanotechnology-based non-viral vectors have been proposed as potential candidates. Various polymeric nanoparticles have been shown to be suitable, with high cellular uptake efficiencies and reduced cytotoxicity. These delivery vectors form condensed complexes with DNA which result in shielding against enzymatic degradation and enhanced cellular targeting. Advantages including easy manipulatibility, high stability, low cost and high payload, mean that nanoparticles from various polymers have been exploited. Gene therapy gives a systematic account of the many aspects of nanotechnology mediated gene therapy, from the preparation of nanoparticles to physicochemical characterization, and follows with applications in in vitro and in vivo models. This book emphasizes the various aspects of nanotechnology-based gene therapy, with initial chapters detailing the tools and techniques available for preparation and in vitro and in vivo characterization of nanoparticles. Later chapters provide exhaustive details on polymeric systems employed for gene therapy.

Nanorobots can be defined as intelligent systems with overall dimensions at or below the micrometer range that are made of assemblies of nanoscale components with individual dimensions ranging between 1 to 100 nm. These devices can now perform a wide variety of tasks at the nanoscale in a wide variety of fields including but not limited to fields such as manufacturing, medicine, supply chain, biology, and aerospace. Nanorobotics: Current Approaches and Techniques offers a comprehensive overview of this emerging interdisciplinary field with a wide ranging discussion that includes nano-manipulation and industrial nanorobotics, nanorobotic manipulation in biology and medicine, nanorobotic sensing, navigation and swarm behavior and CNT, and protein and DNA-based nanorobotics.