Nanoscale Surface Modification For Enhanced Biosensing

This book gives a comprehensive overview of electrochemical-based biosensors and their crucial components. Practical examples are given throughout the text to illustrate how the performance of electrochemical-based biosensors can be improved by nanoscale surface modification and how an optimal design can be achieved. All essential aspects of biosensors are considered, including electrode functionalization, efficiency of the mass transport of reactive species, and long term durability and functionality of the sensor. This book also: · Explains how the performance of an electrochemical-based biosensor can be improved by nanoscale surface modification · Gives readers the tools to evaluate and improve the performance of a biosensor with a multidisciplinary approach that considers electrical, electrostatic, electrochemical, chemical, and biochemical events · Links the performance of a sensor to the various governing physical and chemical principles so readers can fully understand how a biosensor with nanoscale modified electrode surface functions.

Nanobiosensors for Bio-molecular Targeting presents the latest analytical methods for the detection of different substances in the range of small molecules to whole cells, exploring the advantages and disadvantages of each method. Biosensors combine the component of biological origin and physicochemical detector to show the presence of analytes in a given sample. The use of bionanotechnology has led to a significant advancement in the progression of nanobiosensors and has been effectively used for biomedical diagnosis. Explains the detection techniques used by nanosensors, exploring the strengths and weaknesses of each for the detection of disease Shows how biosensors are used to detect various types of biomolecules Demonstrates how the use of nanomaterials makes biosensors both cheaper and more efficient

Based on the success of the first edition, this second edition continues to build upon fundamental principles of biosensor design and incorporates recent advances in intelligent materials and novel fabrication techniques for a broad range of real world applications. The book provides a multi-disciplinary focus to capture the ever-expanding field of biosensors. Smart Biosensor Technology, Second Edition includes contributions from leading specialists in a wide variety of fields with a common focus on smart biosensor design. With 21 chapters organized in five parts, this compendium covers the fundamentals of smart biosensor technology, important issues related to material design and selection, principles of biosensor design and fabrication, advances in bioelectronics, and a look at specific applications related to pathogen detection, toxicity monitoring, microfluidics and healthcare. Features Provides a solid background in the underlying principles of biosensor design and breakthrough technologies for creating more intelligent biosensors Focusses on material design and selection including cutting-edge developments in carbon nanotubes, polymer nanowires, and porous silicon Examines machine learning and introduces concepts such as DNA-based molecular computing for smart biosensor function Explores the principles of bioelectronics and nerve cell microelectrode arrays for creating novel transducers and physiological biosensors Devotes several chapters to biosensors developed to detect and monitor a variety of toxins and pathogens Offers expert opinions on the future directions, challenges and opportunities in the field

Nowadays, the implementation of novel technological platforms in biosensor-based developments is primarily directed to the miniaturization of analytical systems and lowering the limits of detection. Rapid scientific and technological progress enables the application of biosensors for the online detection of minute concentrations of different chemical compounds in a wide selection of matrixes and monitoring extremely low levels of biomarkers even in living organisms and individual cells. This book, including 16 chapters, characterizes the present state of the art and prospective options for micro and nanoscale activities in biosensors construction and applications.

Annual Review of Nano Research, Volume 3 focuses mainly on nanofabrication, nanomaterials and nanostructures, and energy application of nanomaterials. All the review chapters are contributed by well-published scientists and bring the most recent advancement in selected topics to the readers. This review volume will serve dual purposes: either as an excellent introduction to scientists whose expertise lie in different fields but who are interested in learning about nanotechnology, or as a quick reference for experts active in the field of nanoscience and nanotechnology. Sample Chapter(s). Chapter 1: Nanoscale Biosensors and Biochips (64 KB). Contents: Nanoscale Biosensors and Biochips (W R Leifert et al.); Surface Modifications and Applications of Magnetic and Selective Nonmagnetic Nanoparticles (R Shen & H Yang); Progress in Bionanocomposite Materials (E Ruiz-Hitzky et al.); Mesoporous Silica Nanoparticles: Synthesis and Applications (J L Vivero-Escoto et al.); Nanostructured Mesoporous Materials as Drug Delivery Systems (I Izquierdo-Barba et al.); Chemical Synthesis, Self-Assembly and Applications of Magnetic Nanoparticles (S Peng et al.); Recent Development and Applications of Nanoimprint Technology (X Cheng & L J Guo); Three-Dimensional Nanostructure Fabrication by Focused-Ion-Beam Chemical-Vapor-Deposition (S Matsui); Dye-Sensitized Solar Cells Based on Nanostructured Zinc Oxide (Q-F Zhang & G-Z Cao); Nanocomposites as High Efficiency Thermoelectric Materials (S J Thiagarajan et al.); Nanostructured Materials for Hydrogen Storage (S Sepehri & G-Z Cao); Recent Advances in the Characterization of Mesoporous Materials by Physical Adsorption (M Thommes). Readership: Research scientists and engineers in academia, research institutes and industry, as well as graduate students and upper-level undergraduate students in the physical sciences and engineering.

Polymer-Based Nanoscale Materials for Surface Coatings presents the latest advances and emerging technologies in polymer-based nanomaterials for coatings, focusing on novel materials, characterization techniques, and cutting-edge applications. Sections present the fundamentals of surface preparation and nanocoatings, linking materials and properties, explaining the correlation between morphology, surface phenomena, and surface protection mechanism, and covering theory, modeling and simulation. Other presented topics cover characterization methods, with an emphasis on the latest developments in techniques and approaches. Aging and lifecycle assessment of coated surfaces and coatings are also discussed.Final sections explore advanced applications across a range of fields, including intelligent coatings for biomedical implants, self-healing coatings, syper-hydrophobicity, electroluminescence, sustainable edible coatings, marine antifouling, corrosion resistance, and photocatalytic coatings. Explains the fundamentals of coatings and surface protection, mechanisms, materials and properties, and modeling and simulation Presents detailed information on the latest characterization techniques to prepare nanoscale polymer coatings with enhanced properties Explores a broad range of state-of-the-art applications and considers aging and lifecycle assessments of coatings

Biosensors Based on Nanomaterials and Nanodevices links interdisciplinary research from leading experts to provide graduate students, academics, researchers, and industry professionals alike with a comprehensive source for key advancements and future trends in nanostructured biosensor development. It describes the concepts, principles, materials, device fabrications, functions, system integrations, and applications of various types of biosensors based on signal transduction mechanisms, including fluorescence, photonic crystal, surface-enhanced Raman scattering, electrochemistry, electro-luminescence, field-effect transistor, and magnetic effect. The book: Explains how to utilize the unique properties of nanomaterials to construct nanostructured biosensors to achieve enhanced performance Features examples of biosensors based on both typical and emerging nanomaterials, such as gold nanoparticles, quantum dots, graphene, graphene oxides, magnetic nanoparticles, carbon nanotubes, inorganic nanowires/nanorods, plasmonic nanostructures, and photonic crystals Demonstrates the broad applications of nanostructured biosensors in environmental monitoring, food safety, industrial quality assurance, and in vitro and in vivo health diagnosis Inspires new ideas for tackling multiscale and multidisciplinary issues in developing high-performance biosensors for complex practical biomedical problems Focusing on the connection between nanomaterials research and biosensor development, Biosensors Based on Nanomaterials and Nanodevices illustrates the exciting possibilities and critical challenges of biosensors based on nanomaterials and nanodevices for future health monitoring, disease diagnosis, therapeutic treatments, and beyond.