Neuro Urology

This book introduce neurourology as an emerging interdisciplinary area that covers the basic and clinical studies of the neural control on the normal lower urinary tract and the lower/upper urinary tract dysfunction due to neuropathy disorders. It systematically describes all aspects of neurourology from the epidemiology of the neurogenic bladder; to the pathology and pathophysiology of the lower urinary tract; to the diagnosis and treatment of the neurogenic bladder by conservative therapies or surgeries. This book provides a useful resource for medical doctors, nurses and students in the field of neurourological conditions. All the topics are written by internationally recognized specialists in their field.

This volume is a useful handbook for medical doctors involved in the diagnosis and treatment of neuro-urological problems. The first section reviews the relevant neuro-anatomy and neuro-physiology and provides a practical overview of specific neuro-urological pathologic conditions. The second section discusses the various clinical entities that can be encountered and focuses on the clinical entities neuro-urological consquences. The third section is devoted to the different diagnostic possibilities. Internationally accepted algorithms are presented and put into perspective. Section 4 deals with the triad of major clinical problems in this area: urinary (incontinence, retention and voiding dysfunction as well as upper urinary tract problems), anorectal (faecal incontinence and constipation) and sexual (erectile dysfunction and ejaculatory failure) dysfunctions. The final section covers the specific management of patients with neuro-urological problems and describes conservative and surgical treatments, providing the most recent information. Throughout, the text is accompanied by numerous illustrated case reports and discussions as well as tips and tricks based on the personal experience of the different authors.

Emphasizing the clinical problems surrounding urogenital tract dysfunction, this up-to-date reference details the basic science, differential diagnosis, and treatment of a wide range of neurourological conditions. Covering recent advances in the neurobiology of the pelvic organs, the Handbook of Neuro-Urology reviews the neural control processes that govern pelvic organs discusses the pathogenic mechanisms behind neurological and smooth muscle disorders that produce bladder dysfunction describes the management of impaired bladder, bowel, and sexual function after brain damage and spinal cord injury examines various conditions that affect the autonomic nervous system and specifically result in bladder and sexual dysfunction investigates lower urinary tract function in the elderly suggests practical measures to manage urinary incontinence such as the use of pads, underpants, and appliances and more!

Neuro-Urology Research: A Comprehensive Overview describes the current status of the neuro-urology field including the latest discoveries, explains in detail some of the neuroscience tools that can be used when studying the neural control of the lower urinary tract, and discusses potential future directions for research. The first section, Neuroscience in Urology Research, reviews neuro-regulators and the important anatomical brain sites. It also provides an overview of voluntary versus reflex micturition control and describes how bladder physiology readout is a useful tool in research. The second section, Fundamental and Translational Neuro-Urology Research, discusses the translational potential of basic research for patients and the impact of neuro-urology research on clinical practice. Chapters in this section provide more insight into pathologies endemic to specific patient populations and areas for treatment development opportunities. The third section, Neurobiological Tools Applied to Neuro-Urology Research, supplements the ‘A Quick Guide to the "Neuroscience Toolbox"’ and introduces research techniques such as RNA sequencing and calcium imaging of neural activity. The fourth and final section, aptly titled Research Directions and Research Opportunities, covers research directions that remain underexplored or have high therapeutic potential. Research in neuro-urology presents a route to understanding how bladder function is controlled and how urinary continence is maintained. This book provides a platform for researchers to initiate collaborations on the many underexplored research topics and to consolidate knowledge, ultimately lending itself to a coordinated and multi-center research approach that will benefit the field. Presents a comprehensive overview of research studies in the field of neuro-urology Discusses approaches to conducting neuro-urology research, including models of lower urinary tract dysfunction and methods of tracking bladder physiology Proposes areas of research opportunity that, if explored, could yield effective treatment options for those affected by lower urinary tract disorders Includes an introductory guide to useful research tools and the "Neuroscience Toolbox", as well as chapters specifically about RNA sequencing techniques and imaging bladder-associated neural circuits

Emphasizing the clinical problems surrounding urogenital tract dysfunction, this up-to-date reference details the basic science, differential diagnosis, and treatment of a wide range of neurourological conditions. Covering recent advances in the neurobiology of the pelvic organs, the Handbook of Neuro-Urology reviews the neural control processes that govern pelvic organs discusses the pathogenic mechanisms behind neurological and smooth muscle disorders that produce bladder dysfunction describes the management of impaired bladder, bowel, and sexual function after brain damage and spinal cord injury examines various conditions that affect the autonomic nervous system and specifically result in bladder and sexual dysfunction investigates lower urinary tract function in the elderly suggests practical measures to manage urinary incontinence such as the use of pads, underpants, and appliances and more!

This text creates a framework for the integration of urological care into the long-term management of patients with progressive neurological conditions. It begins with a general review of the neuroanatomy and physiology of the bladder, followed by a discussion of common techniques for evaluating bladder and upper tract function, and the general principles of bladder management in patients with neurogenic bladder disease. Section II narrows the scope of each chapter to focus on specific neurological disorders such as Parkinson's Disease, Alzheimer's Disease, Dementia, and Cerebral Palsy. Each chapter begins with a brief synopsis of the neurologic basis of each disease, followed by its most common urologic manifestations, specific recommendations for urologic care in each disease state, and finally a recommended pathway for integrated long-term care of these patients based on available evidence and expert opinion. The final section of the text reviews the generalized care of patients with advanced disease, including palliative and end of life options, focusing on urologic interventions. Urological Care for Patients with Progressive Neurological Conditions will be an invaluable resource for urologists, neurologists, and all health care providers treating patients with neurological diseases.

This volume is a useful handbook for medical doctors involved in the diagnosis and treatment of neuro-urological problems. The first section reviews the relevant neuro-anatomy and neuro-physiology and provides a practical overview of specific neuro-urological pathologic conditions. The second section discusses the various clinical entities that can be encountered and focuses on the clinical entities neuro-urological consquences. The third section is devoted to the different diagnostic possibilities. Internationally accepted algorithms are presented and put into perspective. Section 4 deals with the triad of major clinical problems in this area: urinary (incontinence, retention and voiding dysfunction as well as upper urinary tract problems), anorectal (faecal incontinence and constipation) and sexual (erectile dysfunction and ejaculatory failure) dysfunctions. The final section covers the specific management of patients with neuro-urological problems and describes conservative and surgical treatments, providing the most recent information. Throughout, the text is accompanied by numerous illustrated case reports and discussions as well as tips and tricks based on the personal experience of the different authors.