New Aspects Of Hypertrophic Cardiomyopathy

This extensively updated edition provides a comprehensive review of hypertrophic cardiomyopathy, the most common genetic disorder of the heart characterized by dysfunctional contractility at the sarcomere level. The disease produces abnormal and oftentimes focal hypertrophy on a macroscopic level that further impairs cardiac performance and may lead to life-threatening arrhythmias. This edition provides a practical approach, establishing evidence-based best practice for all scenarios. Hypertrophic Cardiomyopathy provides readers with key points and critical clinical pearls to assist them in managing patients. New chapters have been included on managing hypertension, sleep apnea, coronary artery disease, structural and congenital disease, nutrition and pharmacotherapies. All aspects of treatment are covered – medications, pacemakers and defibrillators, and invasive septal reduction therapy (both surgical myectomy and alcohol septal ablation) – in addition to genetics, family screening, lifestyle concerns, and athletic screening. The practical approach has been reinforced with an expanded emphasis on creating a Center of Excellence, how to facilitate the multi-disciplinary approach, and on case-based reviews and discussions, with each chapter ending with a post-test. This book is an essential text for cardiology professionals from trainee to board-certified physician, and includes important information for interventional cardiologists, cardiac surgeons, cardiac imagers, critical care physicians, sports medicine physicians, genetic counsellors, and electrophysiologists.

Diagnosis and Management of Hypertrophic Cardiomyopathy is aunique, multi-authored compendium of information regarding thecomplexities of clinical and genetic diagnosis, natural history,and management of hypertrophic cardiomyopathy (HCM)—the mostcommon and important of the genetic cardiovasculardiseases—as well as related issues impacting the health oftrained athletes. Edited by Dr. Barry J. Maron, a world authority on HCM, and withmajor contributions from all of the international experts in thisfield, this book provides a single comprehensive source ofinformation concerning HCM. Recent advances in the field arediscussed, including the importance of left ventricular outflowtract obstruction, the use of implantable defibrillators for theprevention of sudden death in young people, definition of thegenetic basis for HCM and its role in clinical diagnosis and riskstratification, the development of more precise strategies forassessing the level of risk for sudden death among all patientswith HCM, and the evolution of invasive interventions for heartfailure symptoms, such as surgical management and its alternatives(alcohol septal ablation and dual-chamber pacing). Key Features: Contributions from all experts in the field,representing diverse viewpoints regarding this heterogeneousdisease and related issues in athletes Information to dispel misunderstandings regarding issuesassociated with HCM and cardiovascular disease in athletes The only comprehensive source of information available on thetopic

Cardiomyopathies are diseases of the heart muscle with diverse etiologies ranging from myocarditis to gene mutations. They are classified according to morphology and function, and then further categorized based on whether they are familial or non-familial and based on specific etiologies. This book examines the various cardiomyopathies, including arrhythmogenic cardiomyopathy, hypertrophic cardiomyopathy, and dilated cardiomyopathy, as well as their genetic basis.

Written by the authority on hypertrophic cardiomyopathy (HCM) and an HCM patient, and fully endorsed by the Hypertrophic Cardiomyopathy Association (HCMA), the leading advocacy and support organization, the 3rd Edition of this best-selling guide offers unparalleled insight into all aspects of living with and treating HCM. Accessible and practical, A Guide to Hypertrophic Cardiomyopathy For Patients, Their Families and Interested Physicians 3rd Edition: Answers the most pressing questions posed by patients, their families, and non-specialists health professionals involved in their care Covers everything from what is HCM and initial diagnosis of this increasingly prevalent condition to the latest treatment options Reflects the first-ever HCM guidelines published by the American Heart Association in 2011

Molecular biology and biochemical techniques, the avant-garde of medical research, are now also being used to investigate cardiovascular events. The fifty-one selected contributions in this volume based on the 14th International Society of Heart Research (ISHR) Meeting in 1992 document the discoveries being made at the frontiers of research with cardiac molecular and genetic biology and technology. The contents may be divided into five categories: 1) the process of ischemic myocardial damage in heart failure, 2) biochemical abnormalities in cardiomyopathy, 3) signal transduction in diseased myocardial cells, 4) electrophysiological abnormalities of the failing heart, and 5) recent concepts in drug therapy. The book builds a bridge for the flow of up-to-date information from active veteran researchers to young talented investigators who offer great promise for the future.