New Directions For Biosciences Research In Agriculture

Authored by an integrated committee of plant and animal scientists, this review of newer molecular genetic techniques and traditional research methods is presented as a compilation of high-reward opportunities for agricultural research. Directed to the Agricultural Research Service and the agricultural research community at large, the volume discusses biosciences research in genetic engineering, animal science, plant science, and plant diseases and insect pests. An optimal climate for productive research is discussed.

In April 1982 the Agricultural Research Service (ARS) of the U.S. Department of Agriculture began a major ongoing review by sponsoring an internal symposium aimed at defining comprehensive, long-range planning goals in bioregulation. The study of the ARS research programs concerned ith bioregulation was to be conducted by the appointed Committee on Biosciences Research in Agriculture. In the committee's view of basic agricultural research as it is conducted within Agricultural Research Service (ARS) laboratories and within organizations throughout the country, three important features determine program planning direction. These are (1) the quickening pace of discovery, (2) the development of new molecular and cellular techniques that enhance current research practices, and (3) the necessity of interdisciplinary collaborations to determine and understand the basic processes of nature, particularly as they relate to efficient plant and animal productivity and health. In realizing how these and other factors will influence the agricultural sciences in the United States for several decades, the ARS has seized the opportunity to reevaluate the structure and substance of its research programs. In the following summary of recommendations the National Research Council's Committee on Biosciences Research in Agriculture suggests ways to focus currently strong basic ARS research programs and identifies areas demanding new or expanded emphasis that will help the agency accomplish its goals.

This report is a congressionally mandated review of the US Department of Agriculture's Research, Education, and Economics (REE) mission area, the main engine of publicly funded agricultural research in the United States. A changing social and scientific context of agriculture requires a new vision of agricultural research-one that will support agriculture as a positive economic, social, and environmental force. REE is uniquely positioned to advance new research frontiers in environment, public health, and rural communities. The report recommends that REE be more anticipatory and strategic in its use of limited resources and guide and champion new directions in research.

"The book...is, in fact, a short text on the many practical problems...associated with translating the explosion in basic biotechnological research into the next Green Revolution," explains Economic Botany. The book is "a concise and accurate narrative, that also manages to be interesting and personal...a splendid little book." Biotechnology states, "Because of the clarity with which it is written, this thin volume makes a major contribution to improving public understanding of genetic engineering's potential for enlarging the world's food supply...and can be profitably read by practically anyone interested in application of molecular biology to improvement of productivity in agriculture."

The State Agricultural Experiment Stations have played a fundamental role in the development of science and agriculture in the United States. From their inception in 1887, the experiment stations have attempted to wed basic research with practical application and have helped institutionalize a utilitarian approach to agricultural science. Agricultural research and the new technology it helped to generate were major factors in the transformation of U.S. agriculture into a high technology, mechanized, science-based industry. Moreover, the experiment stations, as the first large-scale, publicly supported scientific research institutions in the United States, have also long been models for scientific institutions both here and abroad. Compiled for the 1987 centennial of the State Agricultural Experiment Stations, this volume critically examines past performance, current issues, and future directions for public agricultural research in the United States. Each of the authors, drawn from disciplines as diverse as philosophy and agronomy, focuses on a central concern for the scientific enterprise. Issues include priority setting, maintaining and promoting disciplinary and interdisciplinary effectiveness, supporting higher education for agriculture, and efficacious dissemination of research findings. By setting these issues in their historical and philosophical context, the volume suggests new approaches for meeting the continuing challenge to achieve equity, efficiency, sustainability, flexibility, conservation, and consistency with other objectives of U.S. society.

Many developing countries are exploring whether biotechnology has a role in addressing national issues such as food security and environmental remediation, and are considering whether the putative benefits of the technology-for example, enabling greater agricultural productivity and stability in the food supply-outweigh concerns that the technology might pose a danger-to biodiversity, health, and local jobs. Some policy leaders worry that their governments are not prepared to take control of this evolving technology and that introducing it into society would be a risky act. Others have suggested that taking no action carries more risk, given the dire need to produce more food. This book reports on an international workshop held to address these issues. Global Challenges and Directions for Agricultural Biotechnology: Mapping the Course, organized by the National Research Council on October 24-25, 2004, in Washington, DC, focused on the potential applications of biotechnology and what developing countries might consider as they contemplate adopting biotechnology. Presenters at the workshop described applications of biotechnology that are already proving their utility in both developing and developed countries.

Molecular farming is a biotechnological approach that includes the genetic adjustment of agricultural products to create proteins and chemicals for profitable and pharmaceutical purposes. Plant molecular farming describes the manufacture of recombinant proteins and other biologically active product in plants. This approach depends on a genetic transformation of plants that can be accomplished by the methods of stable gene transfer, such as gene transfer to nuclei and chloroplasts, and unstable transfer methods like viral vectors. The requirement for recombinant proteins in terms of quality, quantity, and diversity is increasing exponentially This demand is traditionally met by recombinant protein construction technologies and the engineering of orthodox expression systems based on bacteria or mammalian cell cultures. However, majority of developing countries cannot afford the high costs of medicine derived from such existing methods. Hence, we need to produce not only the new drugs but also the cheaper versions of those already present in the market. Plant molecular farming is considered as a cost-effective technology that has grown and advanced tremendously over the past two decades. This book summarizes the advances and challenges of plant molecular farming for all those who are working on or have an interest in this rapidly emerging area of research.