Nitrogenation Strategy For The Synthesis Of N Containing Compounds

This book focuses on direct nitrogenation strategies to incorporate one or more N-atoms into simple substrates especially hydrocarbons via C–H and/or C–C bond cleavage, which is a green and sustainable way to synthesize nitrogen-containing compounds. The book consists of seven chapters demonstrating interesting advances in the preparation of amines, amides, nitriles, carbamides, azides, and N-heterocyclic compounds and illustrating the mechanisms of these novel transformations. It offers an accessible introduction to nitrogenation reactions for chemists involved in N-compound synthesis and those interested in discovering new reagents and reactions. Ning Jiao is a Professor of Chemistry at Peking University, China.

A comprehensive overview of synthetic strategies for nonaromatic nitrogen heterocycles Nitrogen heterocycles are extremely widely distributed in nature, as well as in synthetic substances found in pharmaceuticals, agrochemicals, and materials chemistry. With new structures and medicines that include these structures emerging yearly, and a vast new journal literature to describe them, anyone who wants to be effective in R&D needs to easily access a synthesis of the latest research. This state-of-the-art survey explores recent developments in the most widely used reactions, as well as completely new ones. Highlights the major modern synthetic methods known to obtain nonaromatic nitrogen heterocycles, and their practical applications Topics include enantioselective synthesis and catalysis, photocatalysis, biocatalysis, microwave-assisted synthesis, reactions of oximes and nitrones, and ionic liquids Discusses how to synthesize rings of specific sizes Covers sustainable synthetic approaches for obtaining salts Whether you are using nonaromatic nitrogen compounds as an academic researcher, a synthetic chemist in industry, or an advanced student, this book is an essential, up-to-date resource to support your work.

Advances in Heterocyclic Chemistry, Volume 129 is the definitive series in the field—one of great importance to organic chemists, polymer chemists and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive, updated release includes chapters on Metal-Catalyzed Direct Arylation of 1,2-Azoles, The Literature of Heterocyclic Chemistry, Part XVII, 2017, Pyrrolo-, Imidazoquinolines and Pyrroloquinazolines with a Bridgehead Nitrogen, Synthesis and Reactions of Arsole, Stibole, and Bismole, Advances in Synthesis and Chemistry of Aziridines, and more. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

The human life is simple as well as quite intrigued and it always tries to find solutions to unending problems and challenges. We know that the need is the mother of invention and the scientists in the world are saints of modern age, as based on their tireless efforts the humans have made a significant progress in various fields as telecommunications, information technology, space technology, infrastructures, food technology through green revolution, life-saving drugs, etc. All these fields need chemicals, which must be manufactured at commercial scales. However, the old technologies are handicapped with unlimited limitations for commercial production of these much needed chemicals. As an old man needs help to cross the road, such limitations in the commercial productions of these chemicals are overcome with co-operative effects of other additives as promoters of reaction rates, which in turn help produce the desired products in quantitative yields. Isn’t it interesting to find out what kind of these promoters are, as they have been identified and successfully used through a long journey of innovative, cost-effective process developments with excellent yields and purities of the targeted molecules, which find number of applications in human life. New technologies with above attributes are the essence of this book entitled as “Aniline and its Analogs”, which covers the old and new methods and technologies of their preparations and manufacturing till date, which is compiled by a versatile and an accomplished scientist.

Nitro chemistry plays an important role in organic synthesis to construct new frameworks. This is due to the diverse properties of the nitro group. The strong electron-withdrawing ability of the nitro group reduces the electron density of the scaffold, facilitating reactions with nucleophiles or electron transfer. In addition, the -hydrogen of the nitro group is highly acidic, giving a stable anion, which facilitates reactions with both electrophilic and nucleophilic reagents. In addition, the nitro group also serves as a good leaving group, which facilitates transformation to a wide variety of functional groups. Despite the substantial contributions of many researchers, nitro chemistry is still an exciting and challenging research area. This book brings together recent original research and review articles contributed by an international team of leading experts and pioneers in organic synthesis using nitro groups. It is sure to provide useful information and promising insights for researchers.

Organic Chemistry Study Guide: Key Concepts, Problems, and Solutions features hundreds of problems from the companion book, Organic Chemistry, and includes solutions for every problem. Key concept summaries reinforce critical material from the primary book and enhance mastery of this complex subject. Organic chemistry is a constantly evolving field that has great relevance for all scientists, not just chemists. For chemical engineers, understanding the properties of organic molecules and how reactions occur is critically important to understanding the processes in an industrial plant. For biologists and health professionals, it is essential because nearly all of biochemistry springs from organic chemistry. Additionally, all scientists can benefit from improved critical thinking and problem-solving skills that are developed from the study of organic chemistry. Organic chemistry, like any "skill", is best learned by doing. It is difficult to learn by rote memorization, and true understanding comes only from concentrated reading, and working as many problems as possible. In fact, problem sets are the best way to ensure that concepts are not only well understood, but can also be applied to real-world problems in the work place. Helps readers learn to categorize, analyze, and solve organic chemistry problems at all levels of difficulty Hundreds of fully-worked practice problems, all with solutions Key concept summaries for every chapter reinforces core content from the companion book

A guide to contemporary advancements in the field of distal C—H functionalization Remote C—H Bond Functionalizations provides a comprehensive overview on the most recent developments in the field of distal C—H functionalization. The text explores how distal C—H functionalization can be applied in various pharmaceutical and agrochemical industries. With contributions from a noted panel of experts on the topic, the book offers a coherent and comprehensive discussion about different strategies. The contributors cover a broad range of topics including C—H functionalization of palladium/norbornene catalysis, ruthenium-catalyzed remote functionalization, the non-directed distal C(sp2)—H, functionalization, transition metal catalyzed distal para-selective C—H functionalization, and much more. The book also includes information on effective strategies as well as the engineering of templates. Throughout the book, the authors lay the foundations for future research. This important book: Contains the most recent research on one of the most important topics in organic synthesis Provides a broad overview on contemporary advancements in the field of distal C—H functionalization Includes deep insights into distal C—H functionalizations Offers information on applications in various industries Written for organic chemists, chemists working with organometallics, and industrial chemists, Remote C—H Bond Functionalizations presents a systematic compilation of the field.

This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.