Nmr Spectroscopy Of Biological Solids
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NMR Spectroscopy of Biological Solids
Author | : A. Ramamoorthy |
Publsiher | : CRC Press |
Total Pages | : 368 |
Release | : 2005-09-22 |
Genre | : Medical |
ISBN | : 9781420027617 |
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Over the past decade, a myriad of techniques have shown that solid-state nuclear magnetic resonance (NMR) can be used in a broad spectrum of applications with exceptionally impressive results. Solid-state NMR results can yield high-resolution details on the structure and function of many important biological solids, including viruses, fibril-formin
Perspectives on Solid State NMR in Biology
Author | : S.R. Kiihne,H.J.M. de Groot |
Publsiher | : Springer Science & Business Media |
Total Pages | : 227 |
Release | : 2013-03-14 |
Genre | : Science |
ISBN | : 9789401725798 |
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Solid state NMR is rapidly emerging as a universally applicable method for the characterization of ordered structures that cannot be studied with solution methods or diffraction techniques. This proceedings -; from a recent international workshop - captures an image of the latest developments and future directions for solid state NMR in biological research, particularly on membrane proteins. Detailed information on how hormones or drugs bind to their membrane receptor targets is needed, e.g. for rational drug design. Higher fields are bringing clear improvements, and the power of solid state NMR techniques for studying amorphous and membrane associated peptides, proteins and complexes is shown by examples of applications at ultra-high fields. Progress in protein expression, experimental design and data analysis are also presented by leaders in these research areas.
Advances in Biological Solid State NMR
Author | : Frances Separovic,Akira Naito |
Publsiher | : Royal Society of Chemistry |
Total Pages | : 632 |
Release | : 2014 |
Genre | : Science |
ISBN | : 9781849739108 |
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Advances in Biological NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid state NMR to studies of membrane interactions and molecular motions
NMR Spectroscopy in Liquids and Solids
Author | : Vladimir I. Bakhmutov |
Publsiher | : CRC Press |
Total Pages | : 0 |
Release | : 2015-04-10 |
Genre | : Medical |
ISBN | : 1482262703 |
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NMR Spectroscopy in Liquids and Solids provides an introduction of the general concepts behind Nuclear Magnetic Resonance (NMR) and its applications, including how to perform adequate NMR experiments and interpret data collected in liquids and solids to characterize molecule systems in terms of their structure and dynamics. The book is composed of ten chapters. The first three chapters consider the theoretical basis of NMR spectroscopy, the theory of NMR relaxation, and the practice of relaxation measurements. The middle chapters discuss the general aspects of molecular dynamics and their relationships to NMR, NMR spectroscopy and relaxation studies in solutions, and special issues related to NMR in solutions. The remaining chapters introduce general principles and strategies involved in solid-state NMR studies, provide examples of applications of relaxation for the determination of molecular dynamics in diamagnetic solids, and discuss special issues related to solid state NMR— including NMR relaxation in paramagnetic solids. All chapters are accompanied by references and recommended literature for further reading. Many practical examples of multinuclear NMR and relaxation experiments and their interpretations are also presented. The book is ideal for scientists new to NMR, students, and investigators working in the areas of chemistry, biochemistry, biology, pharmaceutical sciences, or materials science.
Biomolecular NMR Spectroscopy
Author | : Andrew J. Dingley,A. J. Dingley,Steven M. Pascal |
Publsiher | : IOS Press |
Total Pages | : 488 |
Release | : 2011 |
Genre | : Medical |
ISBN | : 9781607506942 |
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Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful technique for characterization of biomolecular structures at atomic resolution in the solution state. This timely book, entitled "Biomolecular NMR Spectroscopy," focuses on the latest state-of-the-art NMR techniques for characterization of biological macromolecules in the solid and solution state. The editors, Dr. Andrew Dingley (University of Auckland, New Zealand) and Dr. Steven Pascal (Massey University, New Zealand) have organized the book into four sections, covering the following topics: sample preparation, structure and dynamics of proteins, structure and dynamics of nucleic acids and protein-nucleic acid complexes, and rapid and hybrid techniques--
NMR in Biological Systems
Author | : K.V.R. Chary,Girjesh Govil |
Publsiher | : Springer Science & Business Media |
Total Pages | : 552 |
Release | : 2008-04-01 |
Genre | : Science |
ISBN | : 9781402066801 |
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During teaching NMR to students and researchers, we felt the need for a text-book which can cover modern trends in the application of NMR to biological systems. This book covers the entire area of NMR in Biological Sciences (Biomolecules, cells and tissues, animals, plants and drug design). As well as being useful to researchers, this is an excellent book for teaching a course on NMR in Biological Systems.
Solid State NMR Spectroscopy for Biopolymers
Author | : Hazime Saitô,Isao Ando,Akira Naito |
Publsiher | : Springer Science & Business Media |
Total Pages | : 455 |
Release | : 2006-08-05 |
Genre | : Science |
ISBN | : 9781402043031 |
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‘‘Biopolymers’’ are polymeric materials of biological origin, including globular, membrane, and fibrous proteins, polypeptides, nucleic acids, po- saccharides, lipids, etc. and their assembly, although preference to respe- ive subjects may be different among readers who are more interested in their biological significance or industrial and/or medical applications. Nevert- less, characterizing or revealing their secondary structure and dynamics may be an equally very important and useful issue for both kinds of readers. Special interest in revealing the 3D structure of globular proteins, nucleic acids, and peptides was aroused in relation to the currently active Structural Biology. X-ray crystallography and multidimensional solution NMR sp- troscopy have proved to be the standard and indispensable means for this purpose. There remain, however, several limitations to this end, if one intends to expand its scope further. This is because these approaches are not always straightforward to characterize fibrous or membrane proteins owing to extreme difficulty in crystallization in the former, and insufficient spectral resolution due to sparing solubility or increased effective molecular mass in the presence of surrounding lipid bilayers in the latter.
Biological NMR Spectroscopy
Author | : John L. Markley,Stanley J. Opella |
Publsiher | : Oxford University Press |
Total Pages | : 375 |
Release | : 1997-01-30 |
Genre | : Science |
ISBN | : 9780195357424 |
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This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.