Noninvasive Diagnostic Techniques In Ophthalmology

Noninvasive Diagnostic Techniques in Ophthalmology explores the special noninvasive tools developed to function as diagnostic indicators and to further our understanding of ocular function. The volume's focus is on new development in instrumentation and techniques for studying the cornea, lens, retina, vitreous, and aqueous dynamics; whereby special attention is given to how each technique has improved our understanding of basic processes and diagnostic capability. Theoretical aspects, possible sources of error, current problems and limitations, safety evaluation, and future applications and directions are considered. Topics examined include ophthalmic image processing; magnetic resonance imaging of the eye and orbit; diagnostic ocular ultrasound; corneal topography; holographic contour analysis of the cornea; wide field and color specular microscopy; use of the Fourier transform method for statistical evaluation of corneal endothelial morphology; confocal microscopy; in vivo corneal redox fluorometry; evaluation of cataract function with the Scheimp-flug camera; fluorescence and Raman spectroscopy of the crystallin lens; in vivo uses of quasi-elastic light scattering; fundus reflectometry; and clinical visual psychophysics measurements. The book offers discussions of fractal analysis of human retinal blood vessel patterns, scanning laser tomography of the living human eye, fundus imaging and diagnostic screening for public health, and digital image processing for ophthalmology, as well as a detailed appendix comprising additional topics and sources.

In the last 10 years, there has been huge progress in the general understanding of ocular disorders due to the availability and development of new in vivo imaging techniques, such as anterior and posterior eye segment optical coherence tomography as well as biochemical methods allowing rapid confirmation of clinical diagnosis.Introducing noninvasive diagnostic methods in ophthalmology led to an improvement in early differential diagnosis of conditions such as corneal dystrophies, dry eye disease, and various retinal and optic nerve diseases.Recent advances in diagnostic methods have also impacted the treatment methods. This book intends to provide the reader with a comprehensive overview of current ocular diagnostic methods, including the theoretical basis as well as practical approaches and usage in clinical practice.

This monograph, comprising contributed articles from experts in their respective fields, covers all the procedures and diagnostic tests in ophthalmology. It examines: the assessment of visual acuity; tonometry; perimetry and ophthalmoscopy; slit lamp examination; and gonioscopy.

In the last 10 years, there has been huge progress in the general understanding of ocular disorders due to the availability and development of new in vivo imaging techniques, such as anterior and posterior eye segment optical coherence tomography as well as biochemical methods allowing rapid confirmation of clinical diagnosis.Introducing noninvasive diagnostic methods in ophthalmology led to an improvement in early differential diagnosis of conditions such as corneal dystrophies, dry eye disease, and various retinal and optic nerve diseases.Recent advances in diagnostic methods have also impacted the treatment methods. This book intends to provide the reader with a comprehensive overview of current ocular diagnostic methods, including the theoretical basis as well as practical approaches and usage in clinical practice.

This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.

During the past several decades, a significant international research effort has been directed towards understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays a critical role in maintaining corneal and conjunctival integrity, protecting against microbial challenge and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in numerous individuals throughout the world, may lead to desiccation of the ocular surface, ulceration and perforation of the cornea, an increased incidence of infectious disease, and potentionally pronounced visual disability and blindness.