Novel Coronavirus 2019

This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing various aspects of COVID-19 infection, including global epidemiology, genome organization, immunopathogenesis, transmission cycle, diagnosis, treatment, prevention, and control strategies, it highlights host-pathogen interactions, host immune response, and pathogen immune invasion strategies toward developing an immune intervention or preventive vaccine for COVID-19. An understanding of the topics covered in the book is imperative in the context of designing strategies to protect the human race from further losses and harm due to SARS-CoV-2 infection causing COVID-19.

COVID-19: The Essentials of Prevention and Treatment elaborates on the ethology, pathogenesis, epidemiology, clinical characteristics, treatment principles, rehabilitation and prevention, and prevention and control measures for COVID-19. Aimed at healthcare workers, and written to be a practical guide, six chapters cover the following aspects of COVID-19: respiratory viruses; pathogenesis; case definitions and diagnosis; treatment; prevention and disease control; and prospects for the management and research of respiratory virus infections. This book gives first-hand information on the prevention, control, diagnosis and treatment of COVID-19. COVID-19 was recognized as a pandemic in March 2020 by the World Health Organization. It is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians working in China, particularly where the outbreak was first identified in Wuhan, have built up knowledge of prevention and control measures, and diagnosis and treatment of this disease. These insights are now globally relevant. The authors of this book are senior physicians specializing in respiratory diseases, pulmonary diseases and critical care medicine, and are all clinical and scientific research experts working in China, with particular experience in Wuhan. Describes the prevention, control, diagnosis and treatment of COVID-19 Offers practical guidance to healthcare professionals for COVID-19 Gives clinical insights in a question and answer format Details first-hand experience in Chinese cities during the initial outbreak Presents insights that healthcare professionals need to prevent, diagnose, and treat COVID-19

In December 2019, the world witnessed the occurrence of a new coronavirus to humanity. The disease spread quickly and became known as a pandemic globally, affecting both society and the health care system, both the elderly and young groups of people, and both the men’s and women’s groups. It was a universal challenge that immediately caused a surge in scientific research. Be a part of a world rising in fighting against the pandemic, the Coronavirus Disease - COVID-19 was depicted in the early days of the pandemic, but updated by more than 200 scientists and clinicians to include many facets of this new infectious pandemic, including i, characteristics, ecology, and evolution of coronaviruses; ii, epidemiology, genetics, and pathogenesis (immune responses and oxidative stress) of the disease; iii, diagnosis, prognosis, and clinical manifestations of the disease in pediatrics, geriatrics, pregnant women, and neonates; iv, challenges of co-occurring the disease with tropical infections, cardiovascular diseases, hypertension, and cancer and to the settings of dentistry, hematology, ophthalmology, and pharmacy; v, transmission, prevention, and potential treatments, ranging from supportive ventilator support and nutrition therapy to potential virus- and host-based therapies, immune-based therapies, photobiomodulation, antiviral photodynamic therapy, and vaccines; vi, the resulting consequences on social lives, mental health, education, tourism industry and economy; and vii, multimodal approaches to solve the problem by bioinformatic methods, innovation and ingenuity, globalization, social and scientific networking, interdisciplinary approaches, and art integration. We are approaching December 2020 and the still presence of COVID-19, asking us to call it COVID (without 19).

Environmental and Health Management of Novel Coronavirus Disease (COVID-19) examines mitigation measures that can be adopted at the time of a novel coronavirus outbreak to lessen environmental contamination and impacts on human health. The book discusses origin, structure and pathogenesis, epidemiology, environmental transmission and the potential spread routes of COVID-19 via surfaces, air, water, wastewater, medical waste and food products. It also covers guidelines and protocols for setting safety conditions to provide adequate health care and reduce the risk of infection in health and non-healthcare settings, along with preventative measures and disinfection technologies. In addition, the book discusses challenges, opportunities and future perspectives, the global crisis, and global consequences on the environment and health. With contributions from experts, this book presents a multidisciplinary reference resource for virologists, microbiologists, public health professionals, environmental health managers and others engaged in the study and mitigation of the environmental and health impacts of the virus. Covers the environmental transmission and spread of COVID-19 Includes environmental disinfection technologies for prevention of COVID-19 Provides guidelines, standards and protocols related to COVID-19

CONTENTS Chapter I A Review: General Outlook of Coronavirus and SARS-CoV-2……1 Chapter II Covid-19: Update Pathogenesis and Clinical Effects……………..19 Chapter III Epidemiology of Covid-19…………………………………………….29 Chapter IV Effect of ACEIs (Angiotensin-Converting Enzyme Inhibitors) and ARBs (Angiotensin II Receptor Blockers) on as Coronavirus Disease 2019 (Covid-19)…………………………………………41 Chapter V Covid-19 and Food Safety…………………………………………….49 Chapter VI “Covid-19” in the Framework of a Dystopian Element…………..59

This book aims to serve the critical interests of the global community by supplying the most current knowledge and understanding of Covid-19 epidemiology, treatment, and prognoses. There was much uncertain and contradictory information published in the first year of the novel coronavirus. The dynamics of COVID-19 have now been realized, including the type of antibodies produced in infected patients and their limited lasting endurance. This book will set the record straight on the concept of “herd immunity” and explore the current vaccine trials taking place in different countries. This comprehensive book will illuminate recent advances regarding COVID-19 and offer a possible roadmap on how to move forward. Frontiers of COVID-19: A Pathophysiology and Epidemiology Roadmap of Novel Coronavirus Disease will be a vital and forward-looking guide for infectious disease clinicians, scientists and researchers, and students at the graduate level.

This volume presents a comprehensive account of the COVID-19 pandemic, also known as the novel coronavirus pandemic, as it happened. Originating in China in late 2019, the COVID-19 outbreak spread across the entire world in a matter of three to four months. This volume examines the first responses to the pandemic, the contexts of earlier epidemics and the epidemiological basics of infectious diseases. Further, it discusses patterns in the spread of the disease; the management and containment of infections at the personal, national and global level; effects on trade and commerce; the social and psychological impact on people; the disruption and postponement of international events; the role of various international organizations like the WHO in the search for solutions; and the race for a vaccine or a cure. Authored by a medical professional and an economist working on the frontlines, this book gives a nuanced, verified and fact-checked analysis of the COVID-19 pandemic and its global response. A one-stop resource on the COVID-19 outbreak, it is indispensable for every reader and a holistic work for scholars and researchers of medical sociology, public health, political economy, public policy and governance, sociology of health and medicine, and paramedical and medical practitioners. It will also be a great resource for policymakers, government departments and civil society organizations working in the area.

This volume discusses the ecology, evolution and pandemic of the coronavirus, as well as its psychosocial, environmental and economic impact. It also offers a general view of the epidemiology, pathogenesis, control and prevention of the coronavirus, while highlighting the global challenge, future threats and clinical management of COVID-19. It also provides insights into biochemistry and laboratory diagnosis. The book will be an excellent resource for clinicians, policymakers, government departments and civil society organizations alike.