Ocular Fluid Dynamics

The chapters in this contributed volume showcase current theoretical approaches in the modeling of ocular fluid dynamics in health and disease. By including chapters written by experts from a variety of fields, this volume will help foster a genuinely collaborative spirit between clinical and research scientists. It vividly illustrates the advantages of clinical and experimental methods, data-driven modeling, and physically-based modeling, while also detailing the limitations of each approach. Blood, aqueous humor, vitreous humor, tear film, and cerebrospinal fluid each have a section dedicated to their anatomy and physiology, pathological conditions, imaging techniques, and mathematical modeling. Because each fluid receives a thorough analysis from experts in their respective fields, this volume stands out among the existing ophthalmology literature. Ocular Fluid Dynamics is ideal for current and future graduate students in applied mathematics and ophthalmology who wish to explore the field by investigating open questions, experimental technologies, and mathematical models. It will also be a valuable resource for researchers in mathematics, engineering, physics, computer science, chemistry, ophthalmology, and more.

This book covers emerging areas in novel design and their hydrodynamic properties relevant to bioreactors, environmental system, electrochemical systems, food processing and biomedical engineering. This book uses an interdisciplinary approach to provide a comprehensive prospective simulation modeling and hydrodynamic study in advanced biotechnological process and includes reviews of the most recent state of art in modeling and simulation of flows in biological process, such as CFD. Written by internationally recognized researchers in the field, each chapter provides a strong introductory section that is useful to both readers currently in the field and readers interested in learning more about these areas.

The Eye, 3rd Edition, Volume lA: Vegetative Physiology and Biochemistry is devoted to the vegetative physiology and biochemistry of the eye. The book reviews significant progress in the anatomy of the eye and its physiological and biochemical aspects, particularly the structure of the tissues concerning the ocular fluid, the flow of aqueous humor, measurement of the intraocular pressure, and the macromolecular composition of the vitreus. This edition is organized into four chapters and begins with an overview of the anatomy of the human eye, paying particular attention to the orbit and adnexa, the eyeball, and motor and supporting apparatus of the eye. The reader is then introduced to the formation of ocular fluid, the structures in immediate contact with it in the ciliary body, and the anatomical aspects of the vascular circulation in the ciliary body. An account of the chemistry of the aqueous humor and factors affecting the intraocular pressure is also given. The book concludes by discussing the structure and function of the vitreus, focusing on the gel vitreus and liquid vitreus, as well as the rheological state and concentration of collagen, NaHA and proteins in the vitreus of various species from humans to frogs. This book is of interest to students and researchers in fields ranging from ocular science to physiology and biochemistry.

This volume presents the latest findings regarding the control of the fluid environments of the eye and brain. The book is comprised of papers presented at a symposium honoring the 80th birthday of Professor Hugh Davson. The contributors are previous students of Hugh Davson who are now leading authorities in the fields of the eye and brain. The eye is considered from its many interfaces, including the role of prostaglandins, blood flow in diabetes, and the vitreous body. Other topics discussed include the role of carbonic anhydrase, cerebrospinal fluid and its drainage, and the development of the blood/brain barrier to macromolecules. The book also shows how recent findings about homologous molecules refute earlier studies with foreign tracers, and offers a fascinating glimpse into the future with a description of the latest imaging techniques used in neurological diagnosis.

ForewordThe human eye offers the extraordinary possibility to visualize and monitor non-invasively, in vivo, in humans, many morphological and haemodynamical features. Therefore, a large amount of data on ocular structures and macro- and micro-circulation can be obtained in a clinical setting during a patient's visit. However, the interpretation of these data remains a very challenging task, since the understanding of the physiology, bio-mechanics and fluid-dynamics of the human eye remains scarce. This unmet gap between the availability of imaging data and their elusive clinical interpretatio...