Oecd Series On Testing And Assessment Revised Guidance Document 150 On Standardised Test Guidelines For Evaluating Chemicals For Endocrine Disruption
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OECD Series on Testing and Assessment Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption
Author | : OECD |
Publsiher | : OECD Publishing |
Total Pages | : 689 |
Release | : 2018-09-03 |
Genre | : Electronic Book |
ISBN | : 9789264304741 |
Download OECD Series on Testing and Assessment Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption Book in PDF, Epub and Kindle
This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals.
OECD Guidelines for Testing of Chemicals
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Author | : Organisation for Economic Co-operation and Development |
Publsiher | : Organisation for Economic Co-operation and Development ; [Montréal : Renouf] |
Total Pages | : 135 |
Release | : 1981 |
Genre | : Chemical industry |
ISBN | : 9264122214 |
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OECD Guidelines for the Testing of Chemicals Section 2 Test No 206 Avian Reproduction Test
Author | : OECD |
Publsiher | : OECD Publishing |
Total Pages | : 12 |
Release | : 1984-04-04 |
Genre | : Electronic Book |
ISBN | : 9789264070028 |
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The purpose of this Test Guideline is to determine the effects on the reproduction of a substance administered with food to birds. Birds are fed a diet containing the test substance in various concentrations for a period of not less than 20 weeks. A ...
OECD Guidelines for the Testing of Chemicals Section 2 Test No 231 Amphibian Metamorphosis Assay
Author | : OECD |
Publsiher | : OECD Publishing |
Total Pages | : 33 |
Release | : 2009-09-08 |
Genre | : Electronic Book |
ISBN | : 9789264076242 |
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This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...
Challenges in Endocrine Disruptor Toxicology and Risk Assessment
Author | : Alexandra Fucic,Alberto Mantovani |
Publsiher | : Royal Society of Chemistry |
Total Pages | : 539 |
Release | : 2020-12-08 |
Genre | : Science |
ISBN | : 9781788017411 |
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Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology - including interactions with other hormone pathways - has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer's disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.
Mixture Toxicity
Author | : Cornelis A. M. van Gestel,Martijs Jonker,Jan E. Kammenga,Ryszard Laskowski,Claus Svendsen |
Publsiher | : CRC Press |
Total Pages | : 312 |
Release | : 2016-04-19 |
Genre | : Medical |
ISBN | : 9781439830093 |
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In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an
OECD Guidelines for the Testing of Chemicals Section 4 Test No 414 Prenatal Developmental Toxicity Study
Author | : OECD |
Publsiher | : OECD Publishing |
Total Pages | : 11 |
Release | : 2018-06-27 |
Genre | : Electronic Book |
ISBN | : 9789264070820 |
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This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...
OECD Guidelines for the Testing of Chemicals Section 4 Test No 426 Developmental Neurotoxicity Study
Author | : OECD |
Publsiher | : OECD Publishing |
Total Pages | : 26 |
Release | : 2007-10-15 |
Genre | : Electronic Book |
ISBN | : 9789264067394 |
Download OECD Guidelines for the Testing of Chemicals Section 4 Test No 426 Developmental Neurotoxicity Study Book in PDF, Epub and Kindle
A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development. The test substance is administered daily, generally orally, to mated females (rats are ...