Oncologic Imaging Bone Tumors

This book aims to provide readers with a sound understanding of the spectrum of radiologic appearances of bone tumors, which reflect histopathology, and the pattern analysis of imaging findings.The first part of the book explains basic concepts and diagnostic parameters, including demographics, lesion location, biological activity, matrix mineralization, and endosteal and periosteal reactions. In the second part, typical and atypical radiologic features of bone tumors are reviewed in detail, with emphasis on the characteristic radiographic and MR imaging findings and reference to schematic drawings and pathologic or operative images when appropriate.The third part focuses on problem solving in cases encountered in real radiology practice and identifies categorical patterns on the basis of radiographic and MR variables and lesion location. Informative cases are illustrated and compared to enhance understanding of differential diagnosis using pattern analysis. The final part of the book helps readers to consolidate what they have learned and to hone their diagnostic reasoning skills by presenting about 30 typical bone tumor cases with questions, answers, and commentary.

Detection and characterization of bone tumors with imaging remains a big challenge for every radiologist notwithstanding the impressive progress achieved by the introduction of several new imaging modalities. Moreover, new concepts in surgical and oncological treatment of these lesions require from the radiologist appropriate and focused answers to the specifc questions asked by the referring physicians in order to choose the best therapeutic approach for the in- vidual patient. Tis comprehensive textbook describes in detail the possibilities and limits of all moda- ties, including MRI, CT, nuclear medicine and interventional radiological procedures, employed for the modern imaging of tumoral and tumor-like lesions of bone. Teir role in the diagnosis, surgical staging, biopsy and assessment of response to therapy is discussed in detail, covering all tumor subtypes as well as their specifc anatomical location.Well selected and technically imp- cable illustrations strongly enhance the didactic value of this work. I am very much indebted and grateful to the three editors: A. Mark Davies, Murali Sundaram and Steven L. J. James, world authorities in musculoskeletal radiology, for their superb scientifc achievement in preparing and editing this wonderful volume as well as for their individual ch- ters. I would also like to thank the large international group of collaborating authors, who are also widely acknowledged for their specifc expertise in the area of bone tumors, for their outstanding contributions.

This book helps readers to overcome the challenges encountered during the imaging diagnosis of soft tissue tumors due to their diversity and the significant overlap in imaging features between different tumors. It does so by fostering familiarization with typical findings and clearly explaining the pattern analysis of soft tissue tumors. The book opens with an overview of diagnostic considerations and discussion of the basic concepts of diagnostic imaging studies and histopathologic examinations. Grading and staging of soft tissue sarcomasare then described.In the second part of the book, radiologic features of soft tissue tumors are reviewed in detail, based on the 2013 WHO classification system.The third part summarizes diagnostic imaging clues, including characteristic imaging findings and radiologic signs that aid in specific diagnosis and differential diagnosis. The book closes by presenting 30 typical cases of soft tissue tumors, with questions, answers, and commentary, in order to help readers to consolidate what they have learned and to hone their diagnostic reasoning skills.

This book is a detailed guide to image interpretation in patients with spine and spinal cord tumors that will enable clinicians and residents to improve their diagnostic abilities. The book opens by introducing basic concepts in the imaging of spinal tumors, namely the compartmental approach and the histologic basis for the different imaging appearances. These concepts are explained with the aid of representative cases and schematic illustrations. The second part of the book represents a “training step” in which various spinal tumors are described in detail, focusing on the imaging findings. Representative cases are presented with radiographic, CT, and MR images; in addition, schematic illustrations and pathologic or operative images are included in selected cases. The third part is a “practice step” describing tips for correct imaging diagnosis. Individual chapters in this part focus on incidence-, age-, location-, and imaging pattern-based approaches to bone, extradural, intradural extramedullary, intramedullary, and pediatric spinal tumors. The presented cases will enhance the reader’s understanding of the different tumor patterns and assist in solving diagnostic problems that may be encountered in daily practice.

Detection and characterization of bone tumors with imaging remains a big challenge for every radiologist notwithstanding the impressive progress achieved by the introduction of several new imaging modalities. Moreover, new concepts in surgical and oncological treatment of these lesions require from the radiologist appropriate and focused answers to the specifc questions asked by the referring physicians in order to choose the best therapeutic approach for the in- vidual patient. Tis comprehensive textbook describes in detail the possibilities and limits of all moda- ties, including MRI, CT, nuclear medicine and interventional radiological procedures, employed for the modern imaging of tumoral and tumor-like lesions of bone. Teir role in the diagnosis, surgical staging, biopsy and assessment of response to therapy is discussed in detail, covering all tumor subtypes as well as their specifc anatomical location.Well selected and technically imp- cable illustrations strongly enhance the didactic value of this work. I am very much indebted and grateful to the three editors: A. Mark Davies, Murali Sundaram and Steven L. J. James, world authorities in musculoskeletal radiology, for their superb scientifc achievement in preparing and editing this wonderful volume as well as for their individual ch- ters. I would also like to thank the large international group of collaborating authors, who are also widely acknowledged for their specifc expertise in the area of bone tumors, for their outstanding contributions.

Magnetic resonance imaging has already become a most valuable imaging modality in the diagnostic work-up of musculoskeletal neoplasms. While high accuracy of MRI for staging purposes has been proven, we will focus in this monograph on the characterization of primary bone and soft tissue tumors by MRI. The major purpose of this monograph is to provide an atlas of magnetic resonance features of primary bone and soft tissue tumors for radiologists, orthopedic surgeons and physiotherapists. The results presented are based on investigations of 94 primary bone and soft tissue tumors and mimicking conditions by magnetic resonance imaging. Although the scale of the material allows for statistical handling, the number of patients per subgroup is too small to come to definite conclusions. We will therefore limit ourselves to the description of and comments on a great number of cases to illustrate the diagnostic potential of this new imaging modality. We would like to thank the anonymous cooperators: referring clinicians, pathologists, nurses, technicians and secretaries whose help enabled us to present this monograph. We would also like to express our gratitude to the firms Siemens AG and Schering AG for technical support.

This book reviews the latest techniques for diagnostics and treatments specific to bone and soft tissue tumors. It focuses on imaging and classification of the bone and soft tissue tumors and how histology and cytogenetic aspects can be used to identify tumors. Each chapter focuses on a specific type of tumor, providing a concise overview of relevant information on their characteristics along with the latest surgical and medical treatments available. Bone Tumors: Diagnosis and Therapy Today is a concise guide to successfully identifying and treating bone and soft tissue tumors, making it a valuable resource for practicing medical professionals and trainees who encounter these patients in their day-to-day practice.

More than ten years have elapsed since the publication of the first edition of Tumors and Tumorlike Lesions of Bone and Joints in 1981. During this period significant progress has been made in diagnosis, and particularly in staging and treatment of bone tumors. In most centers, limb-sparing surgery has replaced the more radical ablative surgery, with or without preoperative chemotherapy. This became possible due to the introduction and increased application of newer high-quality imaging techniques (CT and MRI) and in particular the use of new cytomorphologic methods of diagnosis, especially immunohisto chemistry. These advances in diagnosis and treatment have been reflected by the publication of new editions of several important text books, since their authors - pathologists, orthopedic surgeons, and radiologists - felt the necessity of updating their works in recent years. However, in these publications different criteria of classification were adopted. The number of cases compiled at the Latin American Registry of Bone Pathology increased from 4913 primary bone tumors and more than 1100 tumorlike lesions at the time of publication of the first edition of this book, to 5274 bone tumors and 1665 tumorlike lesions by the end of December 1985, when I finished my work as head of the Registry and occupied the positions of Professor of Orthopedic Pathology at St. Louis University Medical Center and Distinguished Visiting Professor at Rush-Presbyterian-St. Luke's Medical Center in Chicago.