Pain Anesthesia And Analgesia In Common Laboratory Animals

Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane and successful procedural outcomes. * Provides researchers with the most comprehensive and up-to-date review of the use of anesthesia and analgesia in laboratory animals * Thoroughly updated with new material on ferrets, birds, reptiles, amphibians, fish, and invertebrates * Includes hot topic areas such as pain research, ethical issues, legal issues, and imaging studies

Clear guidelines on the proper care and use of laboratory animals are being sought by researchers and members of the many committees formed to oversee animal care at universities as well as the general public. This book provides a comprehensive overview of what we know about behavior, pain, and distress in laboratory animals. The volume explores: Stressors in the laboratory and the animal behaviors they cause, including in-depth discussions of the physiology of pain and distress and the animal's ecological relationship to the laboratory as an environment. A review of euthanasia of lab animals-exploring the decision, the methods, and the emotional effects on technicians. Also included is a highly practical, extensive listing, by species, of dosages and side effects of anesthetics, analgesics, and tranquilizers.

The use of animals in research adheres to scientific and ethical principles that promote humane care and practice. Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. Recognition and Alleviation of Pain in Laboratory Animals, the second of two reports revising the 1992 publication Recognition and Alleviation of Pain and Distress in Laboratory Animals from the Institute for Laboratory Animal Research (ILAR), focuses on pain experienced by animals used in research. This book aims to educate laboratory animal veterinarians; students, researchers and investigators; Institutional Animal Care and Use Committee members; and animal care staff and animal welfare officers on the current scientific and ethical issues associated with pain in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines for recognizing and alleviating pain in laboratory animals, focusing specifically on the following areas: physiology of pain in commonly used laboratory species; pharmacologic and non-pharmacologic principles to control pain; identification of humane endpoints; and principles for minimizing pain associated with experimental procedures. Finally, the report identifies areas in which further scientific investigation is needed to improve laboratory animal welfare.

Key features: Presents practical information in easily accessible ‘bullet point’ format Covers anesthetic machine and related equipment, anesthetic management and monitoring, anesthesia and analgesia pharmacology, euthanasia, and record keeping Written by well-recognized experts in the laboratory animal community Provides extensive references to direct the reader to sources for further study of alternative techniques and their procedures Concludes with a thorough chapter on Regulatory Management of Rodent Anesthesia which has global application Rodents are the most commonly used species in biomedical research. Individuals conducting rodent research are often responsible to ensure that all areas of anesthesia and analgesia are performed humanely. Anesthetic agent selection, anesthetic monitoring, and postoperative pain assessment and management are essential to the institutional animal care and use program and contribute significantly to the 3Rs by reducing pain and/or distress and refining various procedures. The Handbook of Laboratory Animal Anesthesia and Pain Management: Rodents is the first book to capture multiple advances in this important area that greatly impacts various experimental methodologies. Richly illustrated in full color, the book serves as a quick reference source for investigators, veterinarians, technicians, and other animal caretakers charged with the care and use of rodents in a research setting. The unique format of this book also makes it extremely valuable to IACUC members, institutional officials, and occupational health and safety professionals.