Pain In Peripheral Nerve Diseases

The book takes a novel approach to the subject of pain in peripheral nerve disease by bringing together basic scientists and clinicians with an expertise in the field of neuropathic pain. For the first time, the description of clinically relevant diseases, an up-to-date review of the pathophysiology of neuropathic pain and a comprehensive review of therapeutic options are combined in one book. Furthermore, the anatomy and pathology of peripheral nerve is outlined in the context of neuropathic pain. Peripheral nerve disorders causing pain, the mononeuropathies and polyneuropathies are described in detail including up-to-date summaries of pathogenesis and treatment. Two chapters elucidate the pathophysiology of neuropathic pain, one looking at causes in the periphery and one covering central mechanisms. Treatment options are outlined according to current knowledge from evidence-based medicine and a state-of-the-art treatment algorithm is given to facilitate practical management. Clinicians, neurologists and neurologists in training and basic scientists who are interested in pain will profit most from this book. Painful neuropathies are frequently encountered in clinical practice and are difficult to manage. The book helps to better understand and treat those conditions.

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Disorders of the peripheral nervous system (PNS) are the cause of prominent neurological symptoms including weakness, sensory loss, pain and autonomic dysfunction associated with deficits, morbidity and mortality. These disorders may be primary hereditary or cryptogenic neurologic disorders confined to the PNS or part of the pathology of both the central nervous system and the PNS. Most PNS disorders are secondary to other system disorders and may be responsive to treatment of the primary disease. Important advances have been obtained in several areas including molecular genetics, biochemistry, immunology, morphology and physiology that have enhanced our understanding of the causes and consequences of damage to peripheral nerve. Understanding of both these groups of PNS diseases has greatly expanded over recent years and has led to important advances of treatment both to protect and to repair damages of peripheral nerve. This volume provides an overview of the state-of-the-art of examination, diagnosis and treatment of these very diverse disorders and will be of interest to both the research and clinical neuroscience and neurology communities. Covers both hereditary and cryptogenic neurologic disorders Includes advances in the basic science of PNS from molecular genetics, biochemistry, immunology, morphology and physiology Detailed coverage of neuropathy in connective tissue disorders, infectious disorders, metabolic disorders and malignancy

"An excellent companion volume to Dyck and Thomas' authoritative and comprehensive Peripheral Neuropathy, this visually rich resource features illustrated case studies that explore the evaluation and management of the most common peripheral nerve disorders. Leading authorities in the field contribute clues to the diagnosis, clinical features, imaging studies, histopathology, and more for each, case. You'll benefit from new perspectives on the causes of peripheral nerve disorders, helping you to diagnose and treat every condition you're likely to encounter." --Book Jacket.

Featured as a single volume, this is a comprehensive guide to possible nerve entrapment syndromes and their management. Each chapter covers a single nerve, or group of closely related nerves, and goes over the clinical presentation, anatomy, physical exam, differential diagnosis, contributing factors, injection techniques, neurolytic/surgical techniques, treatments of perpetuating factors, and complications. Nerve entrapments can occur throughout the body and cause headaches, chest pain, abdominal pain, pelvic pain, low back pain, and upper and lower extremity pain. As an example, one of the most common forms of nerve entrapment syndrome, Carpal Tunnel Syndrome, affects roughly 1 in 20 people in the United States, and is only one of several types of entrapment syndromes possible for the median nerve. Chapters are also extensively illustrated and include 3D anatomical images. The additional online material enhances the book with more than 50 videos - at least 2 for each nerve. This enables readers to easily navigate the book. In addition to a conventional index it includes a “Pain Problems Index” for searching by symptom. Peripheral Nerve Entrapments: Clinical Diagnosis and Management is a long-needed resource for pain physicians, emergency room physicians, and neurologists.

Nerves and Nerve Injuries is a must-have for clinicians and researchers dealing with the Peripheral Nervous System and neuropathy. An indispensable work for anyone studying the nerves or treating patients with nerve injuries, these books will become the ‘go to’ resource in the field. The nerves are treated in a systematic manner, discussing details such as their anatomy (both macro- and microscopic), physiology, examination (physical and imaging), pathology, and clinical and surgical interventions. The authors contributing their expertise are international experts on the subject. The books cover topics from detailed nerve anatomy and embryology to cutting-edge knowledge related to treatment, disease and mathematical modeling of the nerves. Nerves and Nerve Injuries Volume 2 focuses on pain, treatment, injury, disease and future directions in the field. This volume also addresses new information regarding neural interfaces, stem cells, medical and surgical treatments, and medical legal issues following nerve injury. Most up-to-date comprehensive overview available on nerves and nerve injuries Comprehensive coverage of nerve injuries on bones, joints, muscles, and motor function; and offers an approach to the treatment of nerve injuries Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available Covers surgical exposure of the nerves including technical aspects of nerve repair and medicinal treatment of nerve injuries Discusses the future of our understanding of the nerves including axonal modeling, synthetic interfaces and brain changes following nerve injury

This 1998 book was the first to be dedicated to peripheral neuropathies of immune or infectious origin, covering pathogenesis, diagnosis and treatment.

Neuropathic pain is one of the most common, most debilitating, most costly, and most difficult to treat categories of chronic pain conditions that are characterized by a lesion or disease of the somatosensory nervous system. Managing neuropathic pain is challenging and requires skillful assessment and comprehensive and integrated treatment strategies that are mechanism-guided, evidence-based, and individualized. However, these critical and integral elements are very fragmented in the current literature. The mechanistic understanding of neuropathic pain is typically found in basic research articles. Clinical research evidence is presented in forms of clinical trials with emphasis on minimizing biases such as those from patient selection and assessment. Individualized considerations for each patient are usually presented in case reports and problem-based learning discussions. This book overcomes these barriers and integrates all the critical elements around individual patient care into a coherent management strategy that is practical and applicable to daily clinical practice. Rather than compiling what have been published in the literature, this work emphasizes on identifying and highlighting the key points or findings that guide decision-making in clinical practice. It integrates the key points around a typical case scenario that not only represents the core of the diagnostic and therapeutic processes but also allows introduction and differentiation of painful conditions that bare similarities with the case in hand. The overarching goal is to improve clinical outcomes through better understanding of the mechanisms, more accurate diagnosis, and wiser and more comprehensive treatment strategies.