Paradigm Shift

A paradigm shift is a sudden, major change in the way you view something, brought on by new information or a new detail that was formerly unknown. Paradigm shifts occur in every area of life, dramatically impacting everyone they touch and leaving a legacy of large-scale transformation in their path. This book is about seven such paradigm shifts, seven major emerging changes, that will rock the world in the years and decades just ahead. If you don't already know about these seven shifts and use them in your daily leadership, you're already behind the curve. These seven new realities are remaking the world in their image. Understanding them is essential to being an effective leader.

Concurrent Engineering is based on the concept that different phases of a product life cycle should be conducted concurrently and initiated as early as possible within the Product Creation Process (PCP). Its main goal is to increase the efficiency and effectiveness of the PCP and reduce errors in the later stages, and to incorporate considerations for the full lifecycle, through-life operations, and environmental issues of the product. It has become the substantive basic methodology in many industries, and the initial basic concepts have matured and become the foundation of many new ideas, methodologies, initiatives, approaches and tools. This book presents the proceedings of the 24th ISPE Inc. International Conference on Transdisciplinary (formerly: Concurrent) Engineering (TE 2017), held in Singapore, in July 2017. The 120 peer-reviewed papers in the book are divided into 16 sections: air transport and traffic operations and management; risk-aware supply chain intelligence; product innovation and marketing management; human factors in design; human engineering; design methods and tools; decision supporting tools and methods; concurrent engineering; knowledge-based engineering; collaborative engineering; engineering for sustainability; service design; digital manufacturing; design automation; artificial intelligence and data analytics; smart systems and the Internet of Things. The book provides a comprehensive overview of recent advances in transdisciplinary concurrent engineering research and applications, and will be of interest to researchers, design practitioners and educators working in the field.

Canada has always been a global nation, integrated with the international economy and having close relations with succeeding hegemonic powers. Recently, globalization was accompanied by an intellectual paradigm shift: moderate state interventionism associated with Keynesian economic theories was replaced by an economic orthodoxy that confined the state to a minimal role and trumpeted the virtue of market solutions. Paradigm Shift evaluates the globalization debate through a Canadian lens and places Canada in the forefront of the analysis. Opposition to neo-liberal globalization emerged on several fronts: from political opposition within civil society and social movements, skepticism about the claims of the globalizers from academic researchers, and lack of enthusiasm by some nation-states which found, contrary to expectations, that they retained some power. The Bush administration s aggressive unilateral foreign policy stimulated talk of a new imperialism and sharpened the debate over the nature of the new era. Canada faces difficult choices but so far the government shows intensified rather than lessened enthusiasm for removing obstacles to trade and investment. On the other hand, as the government moves toward greater integration with the United States, many Canadians seek a more independent path."

Thirty-five-year-old Hank Foster, a former Special Forces soldier still reeling over the loss of his leg in combat, is recruited into a clandestine organization dedicated to attacking religious institutions. Impatient with the movement's slow progress, Hank subverts the powerful organization and uses their vast network to perpetrate a hoax he feels will rock the world and push the Iconoclast organization's agenda into the spotlight. The hoax succeeds beyond his wildest dreams and sets into motion a chain of events that bring a real extraterrestrial presence into the open. Earth is rocked by global catastrophe on a level never before imagined, and humanity is confronted by the prospect of alien invasion. Hank discovers a conspiracy as old as time itself. He learns he is responsible for the calamity facing humanity, and what's more, he learns he is the one man capable of exposing the truth that may lead to mankind's salvation. On its exterior, Paradigm Shift engages the reader with a visual, action-packed, Hollywood-styled blockbuster, but on a deeper, psychological level, the reader is taken along the hero's mythic journey to ultimately confront the true nature of humanity.

PARADIGM SHIFT explores changes in the nature and role of information technology in business in the late 20th century. "This is an important book. Executives who ignore it do so at their own peril. The authors argue persuasively that the information age is entering a second era--one marked by decentralization, empowerment, and affordability. The consequences are both hopeful and far reaching".--Paul Allaire, Chairman and CEO, Xerox Corporation.

A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gallate (EGCG) from green tea, and oleocanthal and oleuropein from olive oil, in addition to a special extract, EGb 761, from the leaves of Ginkgo biloba, the oldest living species of tree on earth. This book also presents a new analytical framework that convincingly favors a multi-targeting ("pleiotropic") approach to the prevention and treatment of complex chronic diseases, in contrast to the mono-targeting of the pharmaceutical model. A Paradigm Shift to Prevent and Treat Alzheimer’s Disease is a unique and exciting resource for pharmaceutical scientists, pharmacologists, neurologists, general practitioners, research scientists in various medical and life sciences, healthcare professionals in clinical and executive positions, conventional medical schools, schools of naturopathic medicine, healthcare and medical journalists, executives in both national public healthcare systems and private insurers, and informed general readers. Presents carefully compiled evidence supporting the need to shift from pharmaceutical-based mono-targeting to plant polyphenol-based pleiotropic targeting for the prevention and treatment of Alzheimer’s disease Includes valuable tables that aggregate pleiotropic pharmacological effects of the plant polyphenols on Alzheimer’s disease-related pathogenic hallmarks Highlights regulatory aspects and discusses the challenges and potential solutions with respect to bioavailability of certain plant polyphenols

This is a brief history in three parts of a new paradigm understanding called The Three Principles, and its dissemination, which was uncovered by Sydney Banks in the 1970s and very gradually and silently crept into the consciousness of perhaps hundreds of thousands of people, touching and changing lives worldwide. It all began when one man, Sydney Banks, in one moment of time, had a profound experience of spiritual enlightenment. A small circle of people gathered around him on Salt Spring Island, British Columbia to listen to his wisdom. Within a few years two mental health professionals became profoundly touched by Syd’s teachings, among them George Pransky. Part I of this book is an extensive interview with Dr. Pransky, who began to create an entirely new, inside-out psychological paradigm. It began to spread little by little, one person at a time, solidly through individual insights and slowly began to infiltrate the fields of mental health, prevention, corrections, business, education, coaching and many more. It began to spread around the world. Part II is a historical chronology of what transpired. Part III consists of brief write-ups of a few of the important historical events that for an extended period of time changed mainstream systems. How difficult it must have been to create an entirely new psychology from the formless, spiritual nature of which Syd Banks spoke, and for which he, himself, even struggled to find words! Furthermore, this became a completely new psychology—a true paradigm shift to the inside-out—which flew in the face of the traditional psychology accepted not only by the powers that be but by millions of people around the world who studied it and practice it. And all this from one man’s enlightenment experience in one moment of time, which gradually rippled out affecting one person at a time, who then affected others, then others, changing lives along the way, and it still grows on into unimaginable futures.