Particle Characterization Light Scattering Methods

Particle characterization is an important component in product research and development, manufacture, and quality control of particulate materials and an important tool in the frontier of sciences, such as in biotechnology and nanotechnology. This book systematically describes one major branch of modern particle characterization technology - the light scattering methods. This is the first monograph in particle science and technology covering the principles, instrumentation, data interpretation, applications, and latest experimental development in laser diffraction, optical particle counting, photon correlation spectroscopy, and electrophoretic light scattering. In addition, a summary of all major particle sizing and other characterization methods, basic statistics and sample preparation techniques used in particle characterization, as well as almost 500 latest references are provided. The book is a must for industrial users of light scattering techniques characterizing a variety of particulate systems and for undergraduate or graduate students who want to learn how to use light scattering to study particular materials, in chemical engineering, material sciences, physical chemistry and other related fields.

Particle Size Analysis reviews the development of particle characterization over the past 25 years and also speculates on its future. Interest in the subject has increased enormously over the years and this book highlights the changes and advances made within the field. This book is comprehensive in its coverage of particle size analysis and includes contributions on such characterization techniques as microscopy using fractal analysis, light diffraction, light scattering with the phase doppler technique, light observation, and photon correlation spectroscopy. A number of chapters address the interest in on-line in-stream particle size analysis and illustrate the progress being made in achieving this long sought after ideal of in-situ in-process particle characterization. Applications to other technological fields are detailed by chapters covering biological systems and the pharmaceutical industry. The subject of surface area determination is considered with particular emphasis on the measurements on porosity of powders, the characterization and comparability of reference materials, and the need for standards. Particle Size Analysis should provide stimulating reading for technologists, scientists, and engineers involved in particle characterization and powder technology worldwide.

The primary aim of this monograph is to provide a systematic state-of-the-art summary of the light scattering of bioparticles, including a brief consideration of analytical and numerical methods for computing electromagnetic scattering by single particles, a detailed discussion of the instrumental approach used in measurement of light scattering, an analysis of the methods used in solution of the inverse light scattering problem, and an introduction of the results dealing with practical analysis of biosamples. Considering the widespread need for this information in optics, remote sensing, engineering, medicine, and biology, the book is useful to many graduate students, scientists, and engineers working on various aspects of electromagnetic scattering and its applications.

This Ph.D. work deals with the scattering of light by a cloud of bubbles (i.e. particles with relative refractive index below unit) near the critical-scattering-angle. Under a single scattering assumption, a critical scattering pattern (CSP) can be accurately modeled with the Lorenz-Mie theory and a Fredholm integral of the first kind. A CSP is basically composed of several bows that are very similar to those observed in the forward diffraction zone and the rainbow region. By measuring the angular spreading, the visibility and the global position of these bows it is possible to deduce the bubbles mean size, poly-dispersion and mean refractive index (i.e. composition). We have developed several inverse methods and experiments to recover these properties, demonstrating the validity of what can be called the "Critical-Angle Refractometry and Sizing" (CARS) technique. Various effects like the laser Gaussian intensity profile or the laser beam spectrum width have also been studied. This new optical particle characterization technique is thought to be a useful tool to study real bubbly flows as well as for laboratory experiments requiring bubbles material recognition.

This book develops the theory of the null-field method (also called T-matrix method), covering almost all aspects and current applications. This book also incorporates FORTRAN programs and simulation results. Worked examples of the application of the FORTRAN programs show readers how to adapt or modify the programs for their specific application.

Dynamic light scattering (DLS) is an important concept that has found applications in the characterization of the biophysical properties of materials for a wide range of applications. DLS studies are extensively employed in material science and engineering to evaluate particle size distribution and surface charge for applications in nanomaterial synthesis, biomolecular analysis, pharmaceutical development and environmental applications. The aim of this book is to provide an overview of research advances relating to the principle and applications of DLS in various fields. The book is divided into two parts Part 1 discusses the uses of DLS in material science and engineering applications and Part 2 focuses on applications of DLS in biological sciences. Chapter 1 aims to provide an overview of the working principle, mathematical models and different types of DLS analysis methods. In addition, recent trends in DLS studies and applications in various fields are also discussed. Chapter 2 discusses the uses of DLS for nanomaterial characterization in terms of the size, size distribution and zeta potential of particles. Chapter 3 compares two techniques (DLS and SAXS) and provides evidence that nanocatalyst can be characterized more effectively by modifying DLS with SAXS. In Chapter 4 the authors demonstrate the application of DLS in characterizing self-assembling and stimuli-responsive di-block copolymers in aqueous media and their association with low molecular weight drugs. Chapter 5 discusses slow and ultraslow dynamics, probed by DLS measurements, in common organic molecular liquids, ionic liquids (ILs), aqueous solutions of salts and molecular solids and liquid-liquid binary mixtures.