Pathogenesis And Clinical Practice In Gastroenterology

The translation of new molecular understanding of disease into clinical practice in gastroenterology is a special challenge. The Falk Symposium No. 160, entitled ‘Pathogenesis and Clinical Practice in Gastroenterology’, held 15-16 June 2007 in Portorož, Slovenia, provided a stimulating framework to bridge discussions from bench to bedside. The proceedings of the symposium are contained in this book, and the unifying theme is the growing understanding of inflammation as a driving force in chronic disease leading to disability and malignancy. Aspects of early detection - endoscopically or via molecular markers - are covered as well as in-depth discussions of the validation of new findings in clinical practice. Whilst on a molecular basis gastroenterologists and hepatologists try to shed light on the same intracellular pathways, clinical implications such as surveillance of cancer in IBD or chronic hepatitis with cirrhosis have to be tailored to specific needs. New therapeutic agents - approved or on the horizon of early clinical studies - will dramatically change the options of patients with chronic disease such as Crohn’s disease, viral hepatitis or hepatocellular carcinoma.

The new, definitive reference text on managing the full range of gastroenterologic disorders, Brandt will become the standard text in the field for all trainee and practising consultant gastroenterologists. Every aspect of every condition in both adults and children, no matter how rare, is covered in-depth in this outstanding new text. Coverage includes full discussion of: * Systemic diseases of the oesophagus * The acute abdomen * Endosonographic evaluation of the gallbladder and bile duct * Munchausen syndrome by proxy * Enteral and parenteral nutrition * Nosocomial infections and their risk to health workers * Surgery in patients with GI and liver disease Relevant clinical information is complemented by state-of-the-art illustrations, including hundreds of charts, graphs, tables and algorithms which summarise information for the busy clinician, and make diagnosis and treatment easier and more accurate. The most up-to-date and comprehensive reference for trainees and consultants Superb art-work programme, detailing even the most complex of procedures Concise and clear text complemented by charts, algorithms, and tables, making diagnosis and management easier

This is the state-of–the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine. This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library.

Gastroenterology is based on its predecessor volume ""The Alimentary Tract"" but the content has been rewritten almost completely. The scope has been expanded to account for major developments in the field of gastroenterology and in order to make the volume more useful to house officers and practicing physicians. The text is designed to be read first, and then summarized if desired with illustrated lectures and demonstrations. This book is organized into 20 chapters. These chapters cover updated gastroenterological topics as of 1982 including symptoms, diagnosis and treatment of diverticular diseases of the colon and lower small intestine; the incidence and distribution of inflammatory bowel diseases; and classification and pathological mechanism of diarrheal disorders. This book will of interest to house officers and practicing physicians.

Evidence-Based Gastroenterology provides a synthesis of evidence-based literature from the field of gastroenterology. Written by an international panel of world-renowned experts, it highlights the most important clinical issues currently facing gastroenterologists. The authors illustrate how they systematically assembled and critically assessed the evidence pertaining to a specific disease. They show how to apply that evidence to problem-solving in daily clinical practice. Supporting evidence is graded using a three-point scale and then further divided into five subcategories. This grading method enables the reader to rapidly identify the optimal approach for specific patient management. What sets Evidence-Based Gastroenterology apart from others in the field is that it allows the reader to see how evidence has been gathered and appraised and how it may be applied in the clinical setting. Evidence-Based Gastroenterology is an extremely valuable resource for those concerned with the pathogenesis, diagnosis, and treatment of a variety of disorders. It identifies important advances and serves as a guide for future research in gastroenterology.

This book uses new thinking on precision medicine and the interplay of genetic factors, the microbiome, and external triggers to build on the core concepts of inflammatory bowel disease. It outlines the latest findings in targeting therapies to the individual patient with Crohn’s and colitis, management of chronic infections in the setting of immunomodulators and biologics, non-surgical therapy of dysplasia in colitis patients, and redefining and structuring the problematic pouch. In addition, this book features useful chapters dedicated to the economic aspects of IBD in an increasingly constrained healthcare system, as well as the patient experience and the role of subspecialist telemedicine care. Written by specialists and thought leaders in the field, Inflammatory Bowel Disease: Pathogenesis, Diagnosis and Management provides a concise but highly relevant account of the latest thinking and concepts in IBD.