Pathogenic Yeasts

Mycological studies of yeasts are entering a new phase, with the sequencing of multiple fungal genomes informing our understanding of their ability to cause disease and interact with the host. At the same time, the ongoing use of traditional methods in many clinical mycology laboratories continues to provide information for the diagnosis and treatment of patients. This volume reviews various aspects of pathogenic yeasts and what is known about their molecular and cellular biology and virulence, in addition to looking at clinical and laboratory findings. As each chapter is written by a leading expert in the field, this book summarizes in one volume much of the latest research on several pathogenic yeasts, including Candida, Cryptococcus, Malassezia and yeasts of emerging importance. The importance of laboratory diagnosis, antifungal susceptibility testing, antifungal resistance and yeast diseases in animals are reviewed.

Pathogenic Yeasts and Yeast Infections focuses on two major yeast genera (Candida and Cryptococcus) and the spectrum of their respective diseases. The book examines the biology of the yeasts, pathogenesis, epidemiology and host response, pathology and clinical symptomatology, diagnosis, and therapy. Genetic studies, morphology, yeast physiology, basic metabolic processes, immunological activity, and the current status of vaccines are addressed as well. In the clinical arena, pathogenesis, pathology, clinical syndromes, organ specificity, diagnostic techniques, and treatment are explored through personal experience and a broad survey of the current literature. The book is authoritative and logically organized for easy reference.

The Yeasts: A Taxonomic Study is a three-volume book that covers the taxonomic aspect of yeasts. The main goal of this book is to provide important information about the identification of yeasts. It also discusses the growth tests that can be used to identify different species of yeasts, and it examines how the more important species of yeasts provide information for the selection of species needed for biotechnology. • Volume 1 discusses the identification, classification and importance of yeasts in the field of biotechnology. • Volume 2 focuses on the identification and classification of ascomycetous yeasts. • Volume 3 deals with the identification and classification of basidiomycetous yeasts, along with the genus Prototheca. High-quality photomicrographs and line drawings Detailed phylogenetic trees Up-to-date, clearly presented yeast taxonomy and systematic, easy-to-use reference sequence accession numbers to allow for correct identification

'... The book is an interesting mixture of both clinical and fundamental mycology.... is illustrated throughout with excellent black and white photographs, clear diagrams and useful tables, and each chapter contains an extensive list of relevant publications. It is an excellent review of many aspects of dimorphisms in yeasts.'

Exploring breakthroughs in fungal detection and control, this book covers fungal nomenclature, population instability, and phylogeny, as well as investigative research on Peronosporomycetes, Zygomycetes, Filamentous Ascomycetes, Basidiomycetous Yeasts, Endomycetes and Blastomycetes, and Miscellaneous Opportunistic Fungi. It offers methods to identi

I belie ve that the book would provide an overview of the recent developments in the domain of yeast research with some new ideas, which could serve as an inspiration and challenge for researchers in this field. Ne w Delhi Prof. Asis Datta Dec. 24, 2007 F ormer Vice-chancellor, JNU Director, NCPGR (New Delhi) Pr eface Yeasts are eukaryotic unicellular microfungi that are widely distributed in the natural environments. Although yeasts are not as ubiquitous as bacteria in the na- ral environments, they have been isolated from terrestrial, aquatic and atmospheric environments. Yeast communities have been found in association with plants, a- mals and insects. Several species of yeasts have also been isolated from specialized or extreme environments like those with low water potential (e. g. high sugar/salt concentrations), low temperature (e. g. yeasts isolated from Antarctica), and low oxygen availability (e. g. intestinal tracts of animals). Around 1500 species of yeasts belonging to over 100 genera have been described so far. It is estimated that only 1% of the extant yeasts on earth have been described till date. Therefore, global efforts are underway to recover new yeast species from a variety of normal and extreme environments. Yeasts play an important role in food chains, and carbon, nitrogen and sulphur cycles. Yeasts can be genetically manipulated by hybridization, mutation, rare m- ing, cytoduction, spheroplast fusion, single chromosomal transfer and transfor- tion using recombinant technology. Yeasts (e. g.

Yeasts and filamentous fungi need to cope with stress, whether growing in the laboratory or in the natural environment, whether victims or offenders in interactions with other organisms. These considerations are discussed in this volume that coveres stress in the broad sense, within the context of mycology. * Includes discussions of the stresses associated with organism-organism interactions and stress under controlled conditions * Anthropogenic stress towards fungi in the environment and the impacts that such stressors may have on different organisms and communities in the wild are explained * Encompasses a breadth of information from the bigger picture of stress effects on fungi in their natural habitats, to the recent advances in underlying molecular-level understanding