Pathophysiology Of Kidney Disease And Hypertension

This new text-a collaborative effort between students and teachers at the University of Wisconsin School of Medicine-provides a unique introductory overview of renal disease, including hypertension and renal transplantation, topics not always covered in other texts. It fully discusses the pathophysiology of renal disorders, using case histories and contemporary data to help you appreciate the mechanisms of these diseases and gain a better understanding of the treatment options available. A consistent chapter format-featuring chapter objectives, key points boxes, and helpful case questions with clinical applications throughout-makes the book user-friendly and easy to reference, while questions at the end of each chapter help you assess your mastery of the material. Discusses significant advances in the field-including those related to pathophysiology of glomerular diseases, electrolyte disorders, renal tubular transport systems, hypertension, transplantation, hereditary diseases, and chronic kidney disease-to keep your knowledge current. Uses a consistent chapter format-featuring chapter objectives, key points boxes, and helpful case questions with clinical applications throughout-to make the book user-friendly and easy to reference. Features questions at the end of each chapter to help you gauge your mastery of the material.

Known worldwide, chronic kidney disease (CKD) is a disease that affects up to 4% of the population with increasing figures also in the developing countries. Life expectancy of patients affected by CKD is shortened compared to the overall population, and only a minority of patients reach end-stage renal disease (ESRD) with the need for dialysis or renal transplantation; death overtakes dialysis. In the 13 chapters, this book sheds light on the different aspects related to pathophysiology and clinical aspects of CKD, providing interesting insights into not only inflammation and cardiovascular risk but also the interplay of hormones and the functional aspects of endothelial function. In addition, chapters dealing with genetic aspects of polycystic kidney disease and also the clinical handling of patients with CKD and peritoneal dialysis will be beneficial for the open-minded reader.

The treatment of hypertension has become the most important intervention in the management of all forms of chronic kidney disease. Chronic Kidney Disease and Hypertension is a current, concise, and practical guide to the identification, treatment and management of hypertension in patients with chronic kidney disease. In depth chapters discuss many relevant clinical questions and the future of treatment through medications and or novel new devices. Written by expert authors, Chronic Kidney Disease and Hypertension provides an up-to-date perspective on management and treatment and how it may re-shape practice approaches tomorrow.

Chronic kidney disease is one of the world's major public health problems, and the prevalence of kidney failure is rising steadily. Among the risk factors for a faster progression of renal disease are hypertension and proteinuria, many studies clearly demonstrating that hypertension is both a cause and consequence of chronic kidney disease. Namely, renal blood pressure regulation seems to be involved in five major pathophysiological mechanisms (all closely related to the renin-angiotensin system): Pressure-natriuresis, renal sympathetic nervous system, renal blood flow, intraglomerular pressure and tubuloglomerular feedback. This book reviews experimental data which form the basis of our current understanding of the association between hypertension and kidney diseases: The pathogenesis of increased blood pressure, the mechanisms by which systemic hypertension promotes progressive kidney failure, and the impact of antihypertensive agents on experimental renal mechanisms involved in hypertension. Furthermore, the role of angiotensin II receptor blockers in both the control of systemic blood pressure and the reduction of proteinuria is examined in an attempt to define optimal therapeutic strategies to prevent the otherwise inexorable deterioration of renal function in patients with chronic kidney disease.

Hypertension/high blood pressure affects 1 in every 4 adults in this country. Hypertension is a serious condition that can damage the blood vessels and eventually lead to stroke, heart failure, heart attack, kidney failure and vision problems. Whether you're a newly diagnosed patient, or are a friend or relative of someone suffering from high blood pressure, this book offers help. The only text available to provide both the doctor's and patient's views, 100 Questions & Answers About High Blood Pressure (Hypertension) gives you authoritative, practical answers to your questions. Written by an expert on the subject, with "insider" commentary from actual patients, this book is an invaluable resource for anyone struggling with the medical, psychological, or emotional turmoil of this condition. -- Provided by publisher.

This guide provides a comprehensive review of the full spectrum of hypertension in chronic kidney disease (CKD). Targeted towards the busy practitioner, the focus of this volume is on various therapies and how to lower blood pressure through lifestyle changes. Specialist patient populations and hypertension and causes of hypertension are also covered in detail. Clinically-focused and authoritative, this resource offers a rationalized approach to diagnosing and treating hypertension in CKD.

A complete clinically focused guide to managing the full spectrum of kidney diseases and hypertension A Doody's Core Title! "an up-to-date, accessible guide that covers all major clinical aspects of the adult patient with diseases involving the kidneys and hypertension. Numerous figures and tables are well integrated into structured chapters creating an easy flow of information that helps readers capture key points....In contrast to many other books in this area, this one provides a concise yet comprehensive review of each topic without getting lost in too much detail that interested readers can find in other places. It is a clinically useful tool for anybody interested in the field....Given its concise but comprehensive structure, this book is a great resource for students and residents who want to review basic physiology and pathophysiology but also get up-to-date information on diagnosis and therapy. The wide range of topics also makes it a useful tool for any clinicians at a more senior level who want to quickly review a particular subject. Lastly, due to its easily accessible structure, patients and families seeking medical information also might find it useful. 3 Stars."--Doody's Review Service Presented in the consistent, easy-to-follow CURRENT style, CURRENT Diagnosis & Treatment Nephrology & Hypertension offers incisive, ready-to-use management protocols and valuable therapeutic guidelines -- from authors who are recognized as the field's foremost authorities. Accessible, concise, and up-to-date, CURRENT Diagnosis & Treatment Nephrology & Hypertension features: One-of-a-kind clinical overview of all major diseases and disorders, from end-stage renal disease to primary and secondary hypertension A practical, learn-as-you-go approach to diagnosing and treating renal disorders and hypertension that combines disease management techniques with the latest clinically proven therapies Up-to-date coverage of transplantation medicine and need-to-know interventional procedures An important review of subspecialty considerations: renal disease in the elderly, diabetic nephropathy, critical care nephrology, and dialysis Expert authorship from prominent clinicians in the areas of kidney disease, dialysis, and hypertension