Perinatal Neuroradiology

The novel aim of this book is to illustrate the MR imaging features of the fetal and the neonatal brain by matching prenatal and postnatal images for a wide range of neurological abnormalities. The focus is on both conventional and advanced MR imaging techniques, including high-resolution MR autopsy of the fetal brain. During the past ten years, neuroradiological evaluation of the neonatal and the prenatal brain has advanced tremendously. However, even though they are intrinsically related, these two critical stages in brain development are usually studied and presented separately. In order to have a sound understanding of neonatal brain diseases, detailed knowledge of prenatal brain pathology is immensely helpful; conversely, knowledge of neonatal brain disease is a prerequisite for understanding many fetal brain lesions. Written by experts in the field, Perinatal Neuroradiology will be of value for neuroradiologists and pediatric radiologists, as well as obstetricians and neonatologists.

Fetal and perinatal medicine is a rapidly expanding field, and noninvasive imaging by means of ultrasonography and MRI is playing a major role in refining diagnosis and therapy. Recent technological advances in these imaging modalities now allow unprecedented morphological depiction of the fetus and excellent insight into complex pathologic conditions, as well as yielding superior guidance for therapeutic fetal inter ventions. I am very pleased that Professor F. Avni , a leading international pediatric radiologist, was prepared to take on the challenging task of preparing and editing this comprehen sive and up-to-date overview of our knowledge in the area of fetal and perinatal imaging. He has been successful in engaging well-known experts with outstanding qualifications in fetal imaging to join him in this venture. I would like to congratulate Professor Avni and all contributing authors most sincerely for their excellent work. I am confident that this outstanding volume will meet with great interest not only from general as well as specialized pediatric radiologists but also from neonatologists and pediatricians. I trust it will enjoy the same success as many previous volumes in this series. ALBERT L. BAERT Leuven Preface Fetal and perinatal medicine would not have developed without the extensive use of obstetric ultrasound (US). In order to be efficient, the examination has to be performed very carefully and by sonologists fully conversant with the normal and abnormal development of the fetus.

This exhaustive text covers all aspects of diagnosis and endovascular treatment of neurological and neurosurgical diseases of the pediatric central nervous system starting from their in utero expression. It also includes the vascular malformations of each district and their endovascular treatment. Besides the "normal" imaging techniques the advanced techniques (spectroscopy, diffusion, perfusion, and functional imaging) are covered in detail. Several topics that are often only superficially dealt with in other books are herewith covered in outstanding detail. The volume is richly illustrated with high-quality neuroradiological images, with pathological correlation where applicable. The rich analytic index makes it an easily usable tool in the everyday clinical practice. The book serves both as a reference for specialists (neuroradiologists, radiologists, neurosurgeons, neurologists, pediatricians) and as a teaching text for residents and fellows-in-training.

The definitive reference work on the developing brain from conception through the first year of life, this book provides specialists involved in the management of the fetus and the neonate with the latest information on the developmental neurology and pathology of the developing central nervous system.

This wonderful, profusely illustrated book provides a concise and thoughtful review of all the important diseases of the child's brain. The lesions are well organized into logical categories that help the reader to remember the information conveyed. The important features of each entity are discussed thoroughly. Data from the literature are documented by selected references and are clearly distinguished from the authors' personal experience. The gross pathology of each disease is illustrated by well selected, high quality CT scans and supporting neuroradiological studies. Each caption begins with the relevant clinical data, so the reader understands the clinical context in which the study was obtained. The caption then describes the specific CT features of the case, so the reader learns to interpret the images correctly to arrive at the final diagnosis. By this technique, the authors provide the reader with a large experience in all aspects of pediatric cranial CT and teach him to distinguish properly among the diverse disease states. The authors must be congratulated for their excellence and their me ticulous attention to detail. They have written an important book that brings together the fields of pediatric neurology and pediatric cranial CT, enhancing both. This volume is a necessary addition to the personal and professional libraries of all physicians who care for children: pediatri cians, neurologists, neurosurgeons and radiologists. I feel I am a better physician for having read this text.

Ideal for exam preparation and everyday clinical practice, Fetal, Neonatal and Pediatric Neuroradiology brings you fully up to date with recent advances in knowledge and image quality in this fast-changing field. World-renowned pediatric neuroradiologist Dr. Thierry A. G. M. Huisman, along with expert coauthors Drs. Stephen Kralik, Nilesh Desai, and Avner Meoded, utilizes an easy-to-read, quick-reference format of bulleted lists and high-quality images to enhance your understanding and help you quickly grasp and retain critical information. Balances state-of-the-art images and clinical features pertinent to the diagnosis in a bulleted format for quick reference and identification. Includes more than 400 diagnoses encountered in pediatric, neonatal, and fetal neuroimaging, including brain, head, neck, spine, and metabolic disorders. Features thousands of high-quality MRI, CT, ultrasound, and radiographic images.

Vast experience has been gained over the past decade in safely transporting, monitoring, and imaging neonates, a highly vulnerable patient group. Technological advances in MRI hardware such as higher field strength systems, multi-channel coils, higher gradient performance, and MR compatible incubators with integrated antennae laid the ground for more detailed, higher resolution anatomical MR imaging. This issue provides separate reviews on the use of MR imaging in the evaluation of encephalopathy, postmortems, spinal dysraphia, and inflicted brain injury as well as neonatal neuro MR imaging and MR-guided cardiovascular interventions.

Problem Solving in Neuroradiology, by Meng Law, MD, Peter M. Som, MD and Thomas P. Naidich, MD, is your survival guide to solving diagnostic challenges that are particularly problematic in neuroimaging. With a concise, practical, and instructional approach, it helps you apply basic principles of problem solving to imaging of the head and interventional neck, brain, and spine. Inside, you'll find expert guidance on how to accurately read what you see, and how to perform critical techniques including biopsy, percutaneous drainage, and tumor ablation. User-friendly features, such as tables and boxes, tips, pitfalls, and rules of thumb, place today's best practices at your fingertips, including protocols for optimizing the most state-of-the-art imaging modalities. A full-color design, including more than 700 high-quality images, highlights critical elements to enhance your understanding. Apply expert tricks of the trade and protocols for optimizing the most state-of-the-art imaging modalities and their clinical applications used for the brain and spine—with general indications for use and special situations. Make the most efficient use of modern imaging modalities including multidetector CT, PET, advanced MR imaging/MR spectroscopy (MRS), diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), and perfusion weighted imaging (PWI). Successfully perform difficult interventional techniques such as biopsies of the spine and interventional angiography—key techniques for more accurately diagnosing cerebral vascular disease, aneurysm, and blood vessel malformations—as well as percutaneous drainage and tumor ablation. Know what to expect. A dedicated section is organized by the clinical scenarios most likely to be encountered in daily practice, such as neurodegenerative disease, vascular disease, and cancer. Avoid common problems that can lead to an incorrect diagnosis. Tables and boxes with tips, pitfalls, and other teaching points show you what to look for, while problem-solving advice helps you accurately identify what you see—especially those images that could suggest several possible diagnoses. See conditions as they appear in practice thanks to an abundance of case examples and specially designed full-color, high-quality images which complement the text and highlight important elements. Quickly find the information you need thanks to a well-organized, user-friendly format with templated headings, detailed illustrations, and at-a-glance tables.