Permanent Present Tense

In Permanent Present Tense Suzanne Corkin tells the incredible story of the amnesiac Henry Gustave Molaison - known only as H.M. until his death in 2008 - and what he taught medical science, neuroscience and the world. In 1953, at the age of twenty-seven, Molaison underwent an experimental psychosurgical procedure intended to alleviate his debilitating epilepsy. The outcome was devastating - when Molaison awoke he was unable to form new memories and for the rest of his life would be trapped in the moment. But Molaison's tragedy would prove a gift to humanity, illuminating functions and structures of the brain and revolutionizing the neuroscience of memory. His amnesia became a touchstone for memory impairment in other patients. For nearly five decades, distinguished neuroscientist Suzanne Corkin studied Molaison and oversaw his care. Her account of his life and legacy in Permanent Present Tense reveals an intelligent man who, despite his profound amnesia, was altruistic, friendly, open, and humorous. She explores how his case transformed an entire field, helping to address eternal questions. How do we store and retrieve memories? How do we know that there are different kinds of memory, controlled by different brain circuits? Is our identity bound up with remembering? If you can recall people or events for only a few seconds and cannot learn from the past or plan the future, can you still live a meaningful life? Permanent Present explores the astonishing complexity of the human brain with great clarity, sensitivity, and grace, showing how one man's story challenged our very notions of who we are. Suzanne Corkin is Professor of Behavioral Neuroscience and head of the Corkin Lab at MIT. The author of nine books, Corkin lives in Charlestown, Massachusetts. 'A fascinating account of perhaps the most important case study in the history of neuroscience, rich with implications for our understanding of the brain, our experience, and what it means to be human' Steven Pinker, author of 'How the Mind Works' and 'The Stuff of Thought' 'The best way to understand memory is to witness the ways it can disassemble. In this remarkable book, Suzanne Corkin gifts us with a rare insider's view, revealing how a man who could not remember his immediate past so profoundly influenced science's future' David Eagleman, neuroscientist and New York Times-bestselling author of 'Incognito: The Secret Lives of the Brain' 'Suzanne Corkin has written an enjoyable and sensitive story of H.M.'s life and what it has taught us about memory. Millions of patients have been the source of advances in science but few are celebrated as individuals. We learn through H.M. that 'Our brains are like hotels with eclectic arrays of guests-homes to different kinds of memory, each of which occupies its own suite of rooms' Philip A. Sharp, Institute Professor, Massachusetts Institute of Technology, and winner of the Nobel Prize in Physiology or Medicine 'Drawing on her unique investigations over more than four decades, neuroscientist Suzanne Corkin relates the fascinating story of how one severely amnesic man transformed our understanding of mind, brain, and memory' Howard Gardner, author of 'Multiple Intelligences'

In 1953, 27-year-old Henry Gustave Molaison underwent an experimental "psychosurgical" procedure -- a targeted lobotomy -- in an effort to alleviate his debilitating epilepsy. The outcome was unexpected -- when Henry awoke, he could no longer form new memories, and for the rest of his life would be trapped in the moment. But Henry's tragedy would prove a gift to humanity. As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense, she and her colleagues brought to light the sharp contrast between Henry's crippling memory impairment and his preserved intellect. This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory. The case of Henry -- known only by his initials H. M. until his death in 2008 -- stands as one of the most consequential and widely referenced in the spiraling field of neuroscience. Corkin and her collaborators worked closely with Henry for nearly fifty years, and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent, quiet, and remarkably good-humored man. Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together, yet he was consistently happy to see her and always willing to participate in her research. His case afforded untold advances in the study of memory, including the discovery that even profound amnesia spares some kinds of learning, and that different memory processes are localized to separate circuits in the human brain. Henry taught us that learning can occur without conscious awareness, that short-term and long-term memory are distinct capacities, and that the effects of aging-related disease are detectable in an already damaged brain. Undergirded by rich details about the functions of the human brain, Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half-century of exciting research. With great clarity, sensitivity, and grace, Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and friend.

“Oliver Sacks meets Stephen King”* in this propulsive, haunting journey into the life of the most studied human research subject of all time, the amnesic known as Patient H.M. For readers of The Immortal Life of Henrietta Lacks comes a story that has much to teach us about our relentless pursuit of knowledge. Winner of the PEN/E.O. Wilson Literary Science Writing Award • Los Angeles Times Book Prize Winner NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The Washington Post • New York Post • NPR • The Economist • New York • Wired • Kirkus Reviews • BookPage In 1953, a twenty-seven-year-old factory worker named Henry Molaison—who suffered from severe epilepsy—received a radical new version of the then-common lobotomy, targeting the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry was left profoundly amnesic, unable to create long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today. Patient H.M. is, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves. Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons, as they called themselves, conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide. “An exciting, artful blend of family and medical history.”—The New York Times *Kirkus Reviews (starred review)

This Book Covers The Following Topics: What are “Tenses”? AGREEMENT between SUBJECT and VERB TWENTY-FOUR Auxiliary Verbs REGULAR AND IRREGULAR VERBS PRESENT TENSE Present Indefinite Tense Present Continuous/Progressive Tense Present Perfect Tense Present Perfect Continuous/Progressive Tense PAST TENSE Past Indefinite Tense Past Continuous/Progressive Tense Past Perfect Tense Past Perfect Continuous/Progressive Tense FUTURE TENSE Future Indefinite Tense Future Continuous/Progressive Tense Future Perfect Tense Future Perfect Continuous/Progressive Tense Useful Notes Exercises Sample This: Tenses could be defined as “any of the form of a verb that may be used to show the time of the action or an event or state expressed by the verb”. THERE ARE THREE KINDS OF TENSES: The Past Tense – The form of a verb that usually expresses an action that happened in the past [Action happened before present] The Present Tense – The form of a verb that usually expresses an action that happens at this time [Action happens in present] The Future Tense – The form of a verb that usually expresses an action that will happen in future [Action will happen after present] EACH OF THESE THREE KINDS OF SENTENCES HAS FOUR TYPES OF FORMS: Indefinite or Simple Form Continuous or Progressive Form Perfect Form Perfect Continuous or Perfect Progressive Form EACH OF THESE FOUR TYPES OF FORMS HAS FOUR KINDS OF STATEMENTS: Affirmative Statement -- Used to Show ‘Agreement’ Negative Statement -- Used to Show ‘Disagreement’ Interrogative Statement -- Used to Ask ‘Question’ Interrogative-Negative Statement -- Used to Ask ‘Question’ and Show ‘Disagreement’ Present Indefinite Tense Expresses – Permanent situation [in the past, present and future] Example: Our family lives in Seattle. General truth (fact or statement) Example: Clean water is fundamental to public health. Example: Many barrages have no utility and cause floods. Habitual action [actions that occur regularly] Example: She listens to music every day. ‘Future meaning’ (timetable, planned event, etc.) Example: My shop closes at 9 pm. Example: The train arrives at 7:30 pm. Traditions, rituals, customs Example: Indians celebrate the festival of light in the month of Oct-Nov. Commands and Instructions [Imperative Sentences] [Note: In imperatives, subject ‘you’ remains hidden] Example: Condemn perpetrators of terrorism. Example: Promote values of humanity and tolerance. Example: Tell us about the exact nature of your work. Used in if-clause of present and future real conditional sentences Example: If I go there, I meet him. Example: If things don't work out, we won't be panicked. Headlines in news reporting [Use of simple present tense instead of the simple past tense is common in news headlines] Example: Flight skids on landing at the airport. Example: Thunderstorm brings relief to residents. (A). AFFIRMATIVE PATTERN – subject + first form of main verb + other words Singular Verb is used with the subject ‘He and She’ + All Singular Subjects. Plural Verb is used with the subject ‘I, We, You and They’ + All Plural Subjects. Examples: He/She talks. I/We/You/They talk. We seek opportunities to chart out our own course. The lean margin of victory or defeat gives an impression of a tough contest. Nowadays, voters value development over other issues. They want civic amenities and employment opportunities. (B). NEGATIVE PATTERN – subject + auxiliary verb ‘do/does’ + not + first form of main verb + other words Auxiliary Verb ‘Does’ is used with the subject ‘He and She’ + All Singular Subjects. Auxiliary Verb ‘Do’ is used with the subject ‘I, We, You and They’ + All Plural Subjects. Examples: He/She does not talk. I/We/You/They do not talk. Most buses do not cater to interior parts of the villages. He does not know what to say.

In the aftermath of a shattering illness, Lonni Sue Johnson—a renowned artist who regularly produced covers for The New Yorker, a gifted musician, a skilled amateur pilot, and a joyful presence to all who knew her—lives in a "perpetual now." Lonni Sue has almost no memories of the past and a nearly complete inability to form new ones. Remarkably, however, she retains much of the intellect and artistic skills from her previous life. As such, Lonni Sue's story has become part of a much larger scientific narrative—one that is currently challenging traditional wisdom about how human memory and awareness are stored in the brain. In this probing, compassionate, and illuminating book, award-winning science journalist Michael D. Lemonick tells the unique drama of Lonni Sue Johnson's day-to-day life and explains the groundbreaking revelations about memory, learning, and consciousness her unique case has uncovered. This is his nuanced and intimate look of the science that lies at the very heart of human nature.

This book investigates the question of subjectivity-how people made sense of a world that was supposed to be understood within centrally created ideological frameworks. It brings together the literature of socialism, nationalism and trans-nationalism, and post-colonialism, areas that have been heretofore all too discreet. How states attempt to model subjects, and the negotiation this entails, is the central question of the modern era. It will be of interest to scholars and students in a wide range of subjects from history to anthropology to aesthetics.

BOOKER PRIZE WINNER • NATIONAL BESTSELLER • A novel that follows a middle-aged man as he contends with a past he never much thought about—until his closest childhood friends return with a vengeance: one of them from the grave, another maddeningly present. A novel so compelling that it begs to be read in a single setting, The Sense of an Ending has the psychological and emotional depth and sophistication of Henry James at his best, and is a stunning achievement in Julian Barnes's oeuvre. Tony Webster thought he left his past behind as he built a life for himself, and his career has provided him with a secure retirement and an amicable relationship with his ex-wife and daughter, who now has a family of her own. But when he is presented with a mysterious legacy, he is forced to revise his estimation of his own nature and place in the world.

Drawing on their expertise on personal growth in the workplace and from their experience with couples in their popular workshops, Morrie and Arleah Shechtman present a new approach that challenges common notions about what makes a good marriage work. They recognise that myths about marriage often lead people to aim for unrealistic ideals. Examining eight myths about relationships -- including: Love will carry you through the hard times; You need to work on your relationship if you want it to be good; and Spending lots of time together is very important -- the book also presents contrasting realities to help strengthen the bond. For those working to build a relationship or struggling to hold one together, this book provides powerful new ways to overcome old behaviours and create a new connection that springs from a shared understanding of one another's needs.