Perspectives On Solid State Nmr In Biology
Download Perspectives On Solid State Nmr In Biology full books in PDF, epub, and Kindle. Read online free Perspectives On Solid State Nmr In Biology ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Perspectives on Solid State NMR in Biology
Author | : S.R. Kiihne,H.J.M. de Groot |
Publsiher | : Springer Science & Business Media |
Total Pages | : 227 |
Release | : 2013-03-14 |
Genre | : Science |
ISBN | : 9789401725798 |
Download Perspectives on Solid State NMR in Biology Book in PDF, Epub and Kindle
Solid state NMR is rapidly emerging as a universally applicable method for the characterization of ordered structures that cannot be studied with solution methods or diffraction techniques. This proceedings -; from a recent international workshop - captures an image of the latest developments and future directions for solid state NMR in biological research, particularly on membrane proteins. Detailed information on how hormones or drugs bind to their membrane receptor targets is needed, e.g. for rational drug design. Higher fields are bringing clear improvements, and the power of solid state NMR techniques for studying amorphous and membrane associated peptides, proteins and complexes is shown by examples of applications at ultra-high fields. Progress in protein expression, experimental design and data analysis are also presented by leaders in these research areas.
NMR Spectroscopy of Biological Solids
Author | : A. Ramamoorthy |
Publsiher | : CRC Press |
Total Pages | : 368 |
Release | : 2005-09-22 |
Genre | : Medical |
ISBN | : 9781420027617 |
Download NMR Spectroscopy of Biological Solids Book in PDF, Epub and Kindle
Over the past decade, a myriad of techniques have shown that solid-state nuclear magnetic resonance (NMR) can be used in a broad spectrum of applications with exceptionally impressive results. Solid-state NMR results can yield high-resolution details on the structure and function of many important biological solids, including viruses, fibril-formin
Solid State NMR Studies of Biopolymers
Author | : Anne E. McDermott,Tatyana Polenova |
Publsiher | : John Wiley & Sons |
Total Pages | : 596 |
Release | : 2010-09-20 |
Genre | : Science |
ISBN | : 9780470721223 |
Download Solid State NMR Studies of Biopolymers Book in PDF, Epub and Kindle
The content of this volume has been added to eMagRes (formerly Encyclopedia of Magnetic Resonance) - the ultimate online resource for NMR and MRI. The field of solid state NMR of biological samples [ssNMR] has blossomed in the past 5-10 years, and a cohesive overview of the technology is needed for new practitioners in industry and academia. This title provides an overview of Solid State NMR methods for studying structure dynamics and ligand-binding in biopolymers, and offers an overview of RF pulse sequences for various applications, including not only a systematic catalog but also a discussion of theoretical tools for analysis of pulse sequences. Practical examples of biochemical applications are included, along with a detailed discussion of the many aspects of sample preparation and handling that make spectroscopy on solid proteins successful. About EMR Handbooks / eMagRes Handbooks The Encyclopedia of Magnetic Resonance (up to 2012) and eMagRes (from 2013 onward) publish a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of EMR Handbooks / eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of articles from eMagRes. In consultation with the eMagRes Editorial Board, the EMR Handbooks / eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written (together with updates of some already existing articles) to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this Handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes View other eMagRes publications here
Solid State NMR Studies of Biopolymers
Author | : Anne E. McDermott,Tatyana Polenova |
Publsiher | : John Wiley & Sons |
Total Pages | : 596 |
Release | : 2012-12-19 |
Genre | : Science |
ISBN | : 9781118588888 |
Download Solid State NMR Studies of Biopolymers Book in PDF, Epub and Kindle
The content of this volume has been added to eMagRes (formerly Encyclopedia of Magnetic Resonance) - the ultimate online resource for NMR and MRI. The field of solid state NMR of biological samples [ssNMR] has blossomed in the past 5-10 years, and a cohesive overview of the technology is needed for new practitioners in industry and academia. This title provides an overview of Solid State NMR methods for studying structure dynamics and ligand-binding in biopolymers, and offers an overview of RF pulse sequences for various applications, including not only a systematic catalog but also a discussion of theoretical tools for analysis of pulse sequences. Practical examples of biochemical applications are included, along with a detailed discussion of the many aspects of sample preparation and handling that make spectroscopy on solid proteins successful. About EMR Handbooks / eMagRes Handbooks The Encyclopedia of Magnetic Resonance (up to 2012) and eMagRes (from 2013 onward) publish a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of EMR Handbooks / eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of articles from eMagRes. In consultation with the eMagRes Editorial Board, the EMR Handbooks / eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written (together with updates of some already existing articles) to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this Handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes View other eMagRes publications here
Current Developments in Solid State NMR Spectroscopy
Author | : Norbert Müller,Perunthiruthy K. Madhu |
Publsiher | : Springer Science & Business Media |
Total Pages | : 143 |
Release | : 2013-04-17 |
Genre | : Science |
ISBN | : 9783709137154 |
Download Current Developments in Solid State NMR Spectroscopy Book in PDF, Epub and Kindle
Why to apply solid-state NMR? - By now, we should have learned that NMR is mainly used for the study of molecules in solution, while x-ray diffraction is the method of choice for solids. Based on this fact, the two recent 'NMR-Nobelprizes' went indeed into the liquid phase: my own one eleven years ago, and particularly the most recent one to Kurt Wuthrich. His prize is beyond any doubts very well justified. His contribution towards the study of biomolecules in solution, in their native (or almost native) environment is truly monumental. We all will profit from it indirectly when one of our future diseases will be cured with better drugs, based on the insightful knowledge gained through liquid-state NMR. Two fields of NMR are still left out of the Nobel Prize game: magnetic reso nance imaging (MRI) and solid-state NMR. The disrespect for MRI in Stockholm is particularly difficult to understand; but this is not a subject to be discussed at the present place. Solid-state NMR is the third of the three great fields of NMR, powerful already today and very promising for the near future.
Fluorine in Medicinal Chemistry and Chemical Biology
Author | : Iwao Ojima |
Publsiher | : John Wiley & Sons |
Total Pages | : 640 |
Release | : 2009-03-23 |
Genre | : Science |
ISBN | : 0470744081 |
Download Fluorine in Medicinal Chemistry and Chemical Biology Book in PDF, Epub and Kindle
The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include: Discovery and development of fluorine containing drugs and drug candidates. New and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates. Structural and chemical biology of fluorinated amino acids and peptides. Fluorine labels as probes in metabolic study, protein engineering and clinical diagnosis. Applications of 19F NMR spectroscopy in biomedical research. An appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action. Fluorine in Medicinal Chemistry and Chemical Biology will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research.
Annual Reports on NMR Spectroscopy
Author | : Anonim |
Publsiher | : Academic Press |
Total Pages | : 194 |
Release | : 2020-02-02 |
Genre | : Science |
ISBN | : 9780128209714 |
Download Annual Reports on NMR Spectroscopy Book in PDF, Epub and Kindle
Annual Reports on NMR Spectroscopy, Volume 99, provides an in-depth accounting of progress in nuclear magnetic resonance (NMR) spectroscopy and its many applications. Specific chapters in this new release include Recent Developments in the accurate measurement of NMR Transverse Relaxation Times, NMR Studies of the Binding and Dynamics of Ionic Liquids with Proteins, Recent Developments in 1HNMR Relaxometry, Solid State 19F NMR Studies of Oriented Peptides, and Applications of Nuclides other than 1H and 13C in Solid State NMR Studies of Pharmaceuticals. Serves as the premier resource for learning the new techniques and applications of NMR spectroscopy Provides a key reference for chemists and physicists using NMR spectroscopy to study the structure and dynamics of molecules Covers all aspects of molecular science, including MRI (Magnetic Resonance Imaging)
Biological NMR Spectroscopy
Author | : John L. Markley,Stanley J. Opella |
Publsiher | : Oxford University Press |
Total Pages | : 375 |
Release | : 1997-01-30 |
Genre | : Science |
ISBN | : 9780195357424 |
Download Biological NMR Spectroscopy Book in PDF, Epub and Kindle
This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.